https://scholars.lib.ntu.edu.tw/handle/123456789/627237
標題: | Heart Failure and Patient-Reported Outcomes in Adults With Congenital Heart Disease from 15 Countries | 作者: | CHUN-WEI LU JOU-KOU WANG HSIAO-LING YANG Kovacs, Adrienne H Luyckx, Koen Ruperti-Repilado, Francisco Javier Van De Bruaene, Alexander Enomoto, Junko Sluman, Maayke A Jackson, Jamie L Khairy, Paul Cook, Stephen C Chidambarathanu, Shanthi Alday, Luis Oechslin, Erwin Eriksen, Katrine Dellborg, Mikael Berghammer, Malin Johansson, Bengt Mackie, Andrew S Menahem, Samuel Caruana, Maryanne Veldtman, Gruschen Soufi, Alexandra Fernandes, Susan M White, Kamila Callus, Edward Kutty, Shelby Apers, Silke Moons, Philip |
關鍵字: | adult congenital heart disease; heart failure; patient‐reported outcomes; quality of life | 公開日期: | 3-五月-2022 | 出版社: | WILEY | 卷: | 11 | 期: | 9 | 來源出版物: | Journal of the American Heart Association | 摘要: | Background Heart failure (HF) is the leading cause of mortality and associated with significant morbidity in adults with congenital heart disease. We sought to assess the association between HF and patient-report outcomes in adults with congenital heart disease. Methods and Results As part of the APPROACH-IS (Assessment of Patterns of Patient-Reported Outcomes in Adults with Congenital Heart disease-International Study), we collected data on HF status and patient-reported outcomes in 3959 patients from 15 countries across 5 continents. Patient-report outcomes were: perceived health status (12-item Short Form Health Survey), quality of life (Linear Analogue Scale and Satisfaction with Life Scale), sense of coherence-13, psychological distress (Hospital Anxiety and Depression Scale), and illness perception (Brief Illness Perception Questionnaire). In this sample, 137 (3.5%) had HF at the time of investigation, 298 (7.5%) had a history of HF, and 3524 (89.0%) had no current or past episode of HF. Patients with current or past HF were older and had a higher prevalence of complex congenital heart disease, arrhythmias, implantable cardioverter-defibrillators, other clinical comorbidities, and mood disorders than those who never had HF. Patients with HF had worse physical functioning, mental functioning, quality of life, satisfaction with life, sense of coherence, depressive symptoms, and illness perception scores. Magnitudes of differences were large for physical functioning and illness perception and moderate for mental functioning, quality of life, and depressive symptoms. Conclusions HF in adults with congenital heart disease is associated with poorer patient-reported outcomes, with large effect sizes for physical functioning and illness perception. Registration URL: https://clinicaltrials.gov; Unique identifier: NCT02150603. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627237 | ISSN: | 2047-9980 | DOI: | 10.1161/JAHA.121.024993 |
顯示於: | 醫學系 |
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