https://scholars.lib.ntu.edu.tw/handle/123456789/627755
標題: | SLC2A10 genetic polymorphism predicts development of peripheral arterial disease in patients with type 2 diabetes. SLC2A10 and PAD in type 2 diabetes | 作者: | YI-DER JIANG YI-CHENG CHANG Chiu, Yen-Feng TIEN-JYUN CHANG HUNG-YUAN LI Lin, Wen-Hsing Yuan, Hsiang-Yu Chen, Yuan-Tsong LEE-MING CHUANG |
關鍵字: | TORTUOSITY-SYNDROME; VASCULAR-DISEASE; RISK-FACTORS; LOWER-EXTREMITY; COMPLICATIONS; POPULATION; ASSOCIATION; MUTATIONS; TRAITS | 公開日期: | 25-八月-2010 | 出版社: | BMC | 卷: | 11 | 期: | 1 | 來源出版物: | BMC medical genetics | 摘要: | Recent data indicate that loss-of-function mutation in the gene encoding the facilitative glucose transporter GLUT10 (SLC2A10) causes arterial tortuosity syndrome via upregulation of the TGF-β pathway in the arterial wall, a mechanism possibly causing vascular changes in diabetes. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627755 | ISSN: | 1471-2350 | DOI: | 10.1186/1471-2350-11-126 |
顯示於: | 醫學系 |
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