https://scholars.lib.ntu.edu.tw/handle/123456789/627763
標題: | Trans-ethnic fine mapping identifies a novel independent locus at the 3′ end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population | 作者: | Kuo, Jane Z Sheu, Wayne Huey-Herng Assimes, Themistocles L Hung, Yi-Jen Absher, Devin Chiu, Yen-Feng Mak, Jordan Wang, Jun-Sing Kwon, Soonil CHENG-CHIH HSU Goodarzi, Mark O Lee, I-Te Knowles, Joshua W Miller, Brittany E Lee, Wen-Jane JYH-MING JIMMY JUANG TZUNG-DAU WANG Guo, Xiuqing Taylor, Kent D LEE-MING CHUANG Hsiung, Chao A Quertermous, Thomas Rotter, Jerome I Chen, Yii-Der I |
關鍵字: | Ethnic difference; Genetic association; Type 2 diabetes; GENOME-WIDE ASSOCIATION; RISK LOCI; INSULIN-RESISTANCE; FASTING GLUCOSE; GENE; IGF2BP2; SLC30A8; VISUALIZATION; CDKN2A/B; TRAITS | 公開日期: | 十二月-2013 | 出版社: | SPRINGER | 卷: | 56 | 期: | 12 | 起(迄)頁: | 2619 | 來源出版物: | Diabetologia | 摘要: | Candidate gene and genome-wide association studies have identified ∼60 susceptibility loci for type 2 diabetes. A majority of these loci have been discovered and tested only in European populations. The aim of this study was to assess the presence and extent of trans-ethnic effects of these loci in an East Asian population. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627763 | ISSN: | 0012-186X | DOI: | 10.1007/s00125-013-3047-1 |
顯示於: | 醫學系 |
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