https://scholars.lib.ntu.edu.tw/handle/123456789/627798
Title: | The role of CD8+ T-cell systemic lupus erythematosus pathogenesis: an update | Authors: | PING-MIN CHEN Tsokos, George C |
Keywords: | CD8T cells; lupus; systemic lupus erythematosus; VERSUS-HOST-DISEASE; MURINE LUPUS; AUTOIMMUNITY; GENERATION; PEPTIDE; CONTRIBUTES; SUPPRESSION; INDUCTION; TOLERANCE; EXPANSION | Issue Date: | 1-Nov-2021 | Publisher: | LIPPINCOTT WILLIAMS & WILKINS | Journal Volume: | 33 | Journal Issue: | 6 | Start page/Pages: | 586 | Source: | Current opinion in rheumatology | Abstract: | Systemic lupus erythematosus (SLE) is a serious autoimmune disease with a wide range of organ involvement. In addition to aberrant B-cell responses leading to autoantibody production, T-cell abnormalities are important in the induction of autoimmunity and the ensuing downstream organ damage. In this article, we present an update on how subsets of CD8+ T cells contribute to SLE pathogenesis. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627798 | ISSN: | 1040-8711 | DOI: | 10.1097/BOR.0000000000000815 |
Appears in Collections: | 生物化學暨分子生物學科研究所 |
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