https://scholars.lib.ntu.edu.tw/handle/123456789/628390
標題: | Engineering an integrated electroactive dressing to accelerate wound healing and monitor noninvasively progress of healing | 作者: | Nguyen, Nhien ZONG-HONG LIN Barman, Snigdha Roy Korupalli, Chiranjeevi Cheng, Ji Yen Song, Ni Xuan Chang, Yen Mi, Fwu Long HSIANG-LIN SONG Sung, Hsing Wen Lin, Yu Jung |
關鍵字: | Electroactive dressing | Telemedicine | Triboelectric nanogenerator | Wound healing | Wound monitoring | 公開日期: | 1-八月-2022 | 卷: | 99 | 來源出版物: | Nano Energy | 摘要: | Traditional wound dressings neither promote the cellular activities that heal wounds nor support the monitoring of the progress of that healing. This work develops an engineered electroactive dressing that comprises a layer of polydopamine-crosslinked carboxymethyl chitosan conductive hydrogel and an interdigitated array (IDA) electrode. The dressing is evaluated in a mouse model with a full-thickness skin defect. The conductive hydrogel provides a channel that transmits endogenous bioelectrical signals to the wound; these stimulate electrical stimuli-responsive cells, and thereby accelerate the restoration of the wounded tissue. The IDA electrode detects the electrical resistance or output current across the wounded tissue for the noninvasive real-time monitoring of the overall healing process. This wound monitoring system is integrated with a WIFI-based system for wireless data collection and transmission using a personal smartphone. Such a real-time wound monitoring system can be worn by patients, to whom it issues early warnings of potential infections and it wirelessly sends data on the progression of healing to remote medical staff for dynamic intervention as required. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/628390 | ISSN: | 22112855 | DOI: | 10.1016/j.nanoen.2022.107393 |
顯示於: | 醫學工程學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。