https://scholars.lib.ntu.edu.tw/handle/123456789/628397
Title: | Plumbagin induces the apoptosis of drug-resistant oral cancer in vitro and in vivo through ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction | Authors: | Lin, Chien-Liang Yu, Chung-I TZONG-HUEI LEE Chuang, Jimmy Ming-Jung Han, Kuang-Fen Lin, Chang-Shen Huang, Wan-Ping Chen, Jeff Yi-Fu Chen, Chung-Yi Lin, Mei-Ying Lee, Chien-Hsing |
Keywords: | Drug-resistant oral cancer; Endoplasmic reticulum stress; Mitochondrial dysfunction; Plumbagin; Reactive oxygen species | Issue Date: | 1-Mar-2023 | Publisher: | NLM (Medline) | Journal Volume: | 111 | Start page/Pages: | 154655 | Source: | Phytomedicine : international journal of phytotherapy and phytopharmacology | Abstract: | Oral cancer is one of the leading causes of cancer-related deaths worldwide. Chemotherapy is widely used in the treatment of oral cancer, but its clinical efficacy is limited by drug resistance. Hence, novel compounds capable of overcoming drug-resistance are urgently needed. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/628397 | ISSN: | 09447113 | DOI: | 10.1016/j.phymed.2023.154655 |
Appears in Collections: | 漁業科學研究所 |
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