https://scholars.lib.ntu.edu.tw/handle/123456789/628835
Title: | Sequential Afatinib and Osimertinib in Asian Patients with EGFR Mutation-Positive Non-Small Cell Lung Cancer and Acquired T790M: Combined Analysis of Two Global Non-Interventional Studies | Authors: | Miura, Satoru Jung, Hyun Ae Lee, Shin Yup Lee, Seung Hyeun Lee, Min Ki Lee, Yong Chul Hochmair, Maximilian J Yang, Cheng-Ta Märten, Angela CHIH-HSIN YANG Popat, Sanjay |
Keywords: | EGFR; T790M; afatinib; osimertinib; sequential | Issue Date: | 2022 | Publisher: | DOVE MEDICAL PRESS LTD | Journal Volume: | 15 | Start page/Pages: | 873 | Source: | OncoTargets and therapy | Abstract: | Two recent non-interventional trials, GioTag and UpSwinG, demonstrated encouraging time-to-treatment failure (TTF) and overall survival (OS) in patients with epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) (Del19 or L858R) who received sequential afatinib/osimertinib, especially in Asians. Here, we have undertaken a combined analysis of Asian patients from both studies. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/628835 | ISSN: | 1178-6930 | DOI: | 10.2147/OTT.S362535 |
Appears in Collections: | 腫瘤醫學研究所 |
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