https://scholars.lib.ntu.edu.tw/handle/123456789/629029
標題: | New presentations and exacerbations of immune thrombocytopenia after coronavirus disease 2019 vaccinations: the Taiwan experience | 作者: | SHENG-CHIEH CHOU Chang, Yu-Cheng Liao, Chun-Kai Chen, Tsung-Chih Sun, Kuo-Jui Huang, Wei-Han Wu, Yi-Feng |
關鍵字: | COVID-19; immune suppressants; immune thrombocytopenia; steroid; vaccination | 公開日期: | 19-五月-2022 | 出版社: | TAYLOR & FRANCIS INC | 卷: | 33 | 期: | 4 | 起(迄)頁: | 531 | 來源出版物: | Platelets | 摘要: | Immune thrombocytopenia (ITP) is a condition that is distinct from thrombosis with thrombocytopenia syndrome (TTS) that may also occur after coronavirus disease 2019 (COVID-19) vaccinations. Previous reports revealed an increased ITP incidence after ChAdOx1, a vaccine for COVID-19. Our study aimed to highlight the key features of ITP after COVID-19 vaccination. From April to October 2021, we collected data on 23 patients, including nine men and 14 women, with ITP from five hospitals across Taiwan who received either the ChAdOx1 or mRNA-1273 vaccine before development or exacerbation of ITP. Our findings revealed that both ChAdOx1 and mRNA-1273 vaccines were associated with ITP. Many patients responded well to steroids and immune suppressants, which may also suggest that the nature of thrombocytopenia is more like ITP rather than TTS. Lack of thrombosis, low D-dimer level, and negative anti-PF4 result could help to exclude TTS, which is also a rare but a far more lethal condition. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/629029 | ISSN: | 0953-7104 | DOI: | 10.1080/09537104.2022.2042237 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。