https://scholars.lib.ntu.edu.tw/handle/123456789/629794
標題: | Monocyte Chemoattractant Protein-1 promotes cancer cell migration via c-Raf/MAPK/AP-1 pathway and MMP-9 production in osteosarcoma | 作者: | Liu, Ju-Fang Chen, Po-Chun Chang, Tsung-Ming CHUN-HAN HOU |
關鍵字: | MCP-1; MMP-9; Migration; Osteosarcoma | 公開日期: | 23-十一月-2020 | 出版社: | BMC | 卷: | 39 | 期: | 1 | 來源出版物: | Journal of experimental & clinical cancer research : CR | 摘要: | Osteosarcoma is generally reported among younger individuals and has a very poor prognosis, particularly for the development of metastasis. However, more effective metastatic biomarkers and therapeutic methods are absent. Monocyte chemoattractant protein-1 (MCP-1) is involved in cancer progression and inflammatory recruitment. Although previous studies have reported higher serum MCP-1 levels in patients with osteosarcoma, the role of MCP-1 in osteosarcoma progression remains to be addressed. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/629794 | ISSN: | 1756-9966 | DOI: | 10.1186/s13046-020-01756-y |
顯示於: | 醫學系 |
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