https://scholars.lib.ntu.edu.tw/handle/123456789/630831
Title: | Association of periodontitis and oral microbiomes with Alzheimer's disease: A narrative systematic review | Authors: | Mao, Samantha Huang, Chen-Pang Lan, Hsin Lau, Hing-Ger CHUN-PIN CHIANG YI-WEN CHEN |
Keywords: | Alzheimer’s disease; Cognitive impairment; Oral microbiome; Periodontitis | Issue Date: | Oct-2022 | Publisher: | ELSEVIER TAIWAN | Journal Volume: | 17 | Journal Issue: | 4 | Start page/Pages: | 1762 | Source: | Journal of dental sciences | Abstract: | Alzheimer's disease (AD) is a neurodegenerative disorder and the most common form of dementia. The etiology for AD includes age, genetic susceptibility, neuropathology, and infection. Periodontitis is an infectious and inflammatory disease which mainly causes alveolar bone destruction and tooth loss. The evidence of a link between AD and periodontitis remains controversial. Thus far, studies reviewing the association between AD and periodontal disease have been insufficient from the viewpoint of the oral microbiome. The aim of this review was to focus on studies that have explored the relationship between the oral microbiome and AD development by using the next-generation sequencing technique. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630831 | ISSN: | 1991-7902 | DOI: | 10.1016/j.jds.2022.07.001 |
Appears in Collections: | 臨床牙醫學研究所 |
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