https://scholars.lib.ntu.edu.tw/handle/123456789/630870
標題: | Cisplatin and Albumin-Based Gold-Cisplatin Nanoparticles Enhance Ablative Radiation Therapy-Induced Antitumor Immunity in Local and Distant Tumor Microenvironment | 作者: | JENNY LING-YU CHEN Yang, Shu-Jyuan Pan, Chun-Kai Lin, Li-Cheng Tsai, Ching-Yi Wang, Chung-Hao YU-SEN HUANG Lin, Yu-Li SUNG-HSIN KUO MING-JIUM SHIEH |
公開日期: | 13-二月-2023 | 來源出版物: | International journal of radiation oncology, biology, physics | 摘要: | Ablative radiation therapy (RT) is an important strategy to eliminate primary tumor and can potentially induce the abscopal effect. Human serum albumin nanoparticle (NP) was used for controlled release of cisplatin to decrease cisplatin's systemic toxicity, and gold (Au) was added to increase RT-induced immunogenic cell death and potentiate the abscopal antitumor immunity. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630870 | ISSN: | 03603016 | DOI: | 10.1016/j.ijrobp.2023.02.014 |
顯示於: | 腫瘤醫學研究所 |
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