https://scholars.lib.ntu.edu.tw/handle/123456789/631555
標題: | Hydrops fetalis caused by severe α-thalassemia | 作者: | FON-JOU HSIEH TSANG-MING KO Chen, H. Y. |
關鍵字: | hydrops fetalis | prenatal diagnosis | α-thalassemia | 公開日期: | 1-一月-1992 | 卷: | 29 | 期: | 1-3 | 來源出版物: | Early Human Development | 摘要: | Alpha-thalassemia is a prevalent condition in South East Asia and spreading because of increasing immigration. Hemodynamic study of Hb Bart's hydrops fetalis, the most severe form of a-thalassemia, showed the fetuses were in a hyperdynamic circulatory state and were also more acidotic, hypoxic, and hypercarvic than normal fetuses. The most common molecular defects of Hb Bart's hydrops fetalis was the Southeast Asia type deletion. Prenatal diagnosis of Hb Bart's hydrops fetalis and HbH diseases has been achieved using chorionic villi sampling or fetal blood sampling. © 1992. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/631555 | ISSN: | 03783782 | DOI: | 10.1016/0378-3782(92)90158-D |
顯示於: | 醫學系 |
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