https://scholars.lib.ntu.edu.tw/handle/123456789/631610
標題: | Blood-ocular barriers | 作者: | MUH-SHY CHEN Hou, Ping Kang TONG-YUAN TAI Lin, Boniface Juisiang |
關鍵字: | Blood-aqueous barrier | Blood-ocular barrier | Blood-retinal barrier | 公開日期: | 1-一月-2008 | 卷: | 20 | 期: | 1 | 來源出版物: | Tzu Chi Medical Journal | 摘要: | There are two main blood-ocular barriers, the blood-aqueous barrier and the blood-retinal barrier. The blood-aqueous barrier is formed by the non-pigmented ciliary epithelium of the ciliary body and the vascular endothelium of the iris vessels. The blood-retinal barrier is formed by the vascular endothelium of the retinal vessels and the retinal pigment epithelium. Four methods of examination are currently used to study the function of blood-ocular barriers. Among these, laser flare-cell photometry is a non-invasive, quantitative method to evaluate the permeability of the blood-aqueous barrier. Vitreous fluorophotometry is an excellent technique to quantitate blood-retinal barrier function. Fluorescein angiography and optical coherence tomography are excellent qualitative imaging techniques to evaluate blood-retinal barrier function. Current basic research shows prostaglandin E2 and other mediators may produce breakdown of the blood-aqueous barrier, and vascular endothelial growth factor plays an important role in the breakdown of the blood-retinal barrier. Retinal laser photocoagulation can induce breakdown of both the blood-aqueous and blood-retinal barriers in pigmented rabbits. The four methods of examination described herein are excellent measures for clinical application to evaluate blood-ocular barrier function in various ocular diseases, many of which are discussed here. © 2008 Buddhist Compassion Relief Tzu Chi Foundation. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/631610 | ISSN: | 10163190 | DOI: | 10.1016/S1016-3190(08)60004-X |
顯示於: | 醫學系 |
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