https://scholars.lib.ntu.edu.tw/handle/123456789/633601
標題: | The androgen receptor in bladder cancer | 作者: | Chen, Jinbo Huang, Chi-Ping Quan, Chao Zu, Xiongbing Ou, Zhenyu YU-CHIEH TSAI Messing, Edward Yeh, Shuyuan Chang, Chawnshang |
公開日期: | 18-四月-2023 | 來源出版物: | Nature reviews. Urology | 摘要: | Bladder cancer is the ninth most common cancer worldwide with a striking sex-based difference in incidence. Emerging evidence indicates that the androgen receptor (AR) might promote the development, progression and recurrence of bladder cancer, contributing to the observed sex differences. Targeting androgen-AR signalling has promise as potential therapy for bladder cancer and helps to suppress progression of this disease. In addition, the identification of a new membrane AR and AR-regulated non-coding RNAs has important implications for bladder cancer treatment. The success of human clinical trials of targeted-AR therapies will help in the development of improved treatments for patients with bladder cancer. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/633601 | ISSN: | 17594812 | DOI: | 10.1038/s41585-023-00761-y |
顯示於: | 腫瘤醫學研究所 |
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