https://scholars.lib.ntu.edu.tw/handle/123456789/637493
標題: | Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small cell lung cancer | 作者: | Hsu, Xiu-Rui Wu, Jia-En Wu, Yi-Ying Hsiao, Sheng-Yen Liang, Jui-Lin Wu, Ya-Ju Tung, Chia-Hao Huang, Meng-Fan Lin, Ming-Shiu PAN-CHYR YANG Chen, Yuh-Ling Hong, Tse-Ming |
關鍵字: | EGFR; Exosome; IGF1R; Lnc-MLETA1; Lung cancer metastasis; miR-186-5p; miR-497-5p | 公開日期: | 26-十月-2023 | 卷: | 42 | 期: | 1 | 來源出版物: | Journal of experimental & clinical cancer research : CR | 摘要: | Lung cancer is the most common and deadliest cancer worldwide, and approximately 90% of all lung cancer deaths are caused by tumor metastasis. Tumor-derived exosomes could potentially promote tumor metastasis through the delivery of metastasis-related molecules. However, the function and underlying mechanism of exosomal long noncoding RNA (lncRNA) in lung cancer metastasis remain largely unclear. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/637493 | ISSN: | 1756-9966 | DOI: | 10.1186/s13046-023-02859-y |
顯示於: | 醫學系 |
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