https://scholars.lib.ntu.edu.tw/handle/123456789/638143
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chu, Cheng Hung | en_US |
dc.contributor.author | Chia, Yu-Hsin | en_US |
dc.contributor.author | Hsu, Hung-Chuan | en_US |
dc.contributor.author | Vyas, Sunil | en_US |
dc.contributor.author | Tsai, Chen-Ming | en_US |
dc.contributor.author | Yamaguchi, Takeshi | en_US |
dc.contributor.author | Tanaka, Takuo | en_US |
dc.contributor.author | HUEI-WEN CHEN | en_US |
dc.contributor.author | YUAN LUO | en_US |
dc.contributor.author | PAN-CHYR YANG | en_US |
dc.contributor.author | Tsai, Din Ping | en_US |
dc.date.accessioned | 2023-12-27T02:34:46Z | - |
dc.date.available | 2023-12-27T02:34:46Z | - |
dc.date.issued | 2023-12-01 | - |
dc.identifier.issn | 15306984 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/638143 | - |
dc.description.abstract | Phase contrast imaging techniques enable the visualization of disparities in the refractive index among various materials. However, these techniques usually come with a cost: the need for bulky, inflexible, and complicated configurations. Here, we propose and experimentally demonstrate an ultracompact meta-microscope, a novel imaging platform designed to accomplish both optical and digital phase contrast imaging. The optical phase contrast imaging system is composed of a pair of metalenses and an intermediate spiral phase metasurface located at the Fourier plane. The performance of the system in generating edge-enhanced images is validated by imaging a variety of human cells, including lung cell lines BEAS-2B, CLY1, and H1299 and other types. Additionally, we integrate the ResNet deep learning model into the meta-microscope to transform bright-field images into edge-enhanced images with high contrast accuracy. This technology promises to aid in the development of innovative miniature optical systems for biomedical and clinical applications. | en_US |
dc.language.iso | en | en_US |
dc.publisher | American Chemical Society | en_US |
dc.relation.ispartof | Nano Letters | en_US |
dc.subject | deep learning; edge detection; metasurface; phase contrast imaging | en_US |
dc.title | Intelligent Phase Contrast Meta-Microscope System | en_US |
dc.type | journal article | en_US |
dc.identifier.doi | 10.1021/acs.nanolett.3c03484 | - |
dc.identifier.pmid | 38038680 | - |
dc.identifier.scopus | 2-s2.0-85179785296 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85179785296 | - |
dc.relation.pages | 11630-11637 | en_US |
dc.relation.journalvolume | 23 | en_US |
dc.relation.journalissue | 24 | en_US |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Toxicology | - |
crisitem.author.dept | Genome and Systems Biology Degree Program | - |
crisitem.author.dept | Medical Device and Imaging | - |
crisitem.author.dept | Program for Precision Health and Intelligent Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Clinical Pharmacy | - |
crisitem.author.dept | Oncology | - |
crisitem.author.dept | Biomedical Electronics and Bioinformatics | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-5051-9896 | - |
crisitem.author.orcid | 0000-0001-9776-7897 | - |
crisitem.author.orcid | 0000-0001-6330-6048 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | Graduate School of Advanced Technology | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫療器材與醫學影像研究所 |
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