https://scholars.lib.ntu.edu.tw/handle/123456789/638450
標題: | Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer | 作者: | Dziadziuszko, Rafal Krebs, Matthew G De Braud, Filippo Siena, Salvatore Drilon, Alexander Doebele, Robert C Patel, Manish R Cho, Byoung Chul Liu, Stephen V Ahn, Myung-Ju Chiu, Chao-Hua Farago, Anna F CHIA-CHI LIN Karapetis, Christos S Li, Yu-Chung Day, Bann-Mo Chen, David Wilson, Timothy R Barlesi, Fabrice |
公開日期: | 10-四月-2021 | 卷: | 39 | 期: | 11 | 來源出版物: | Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 摘要: | Genetic rearrangements of the tyrosine receptor kinase ROS proto-oncogene 1 (ROS1) are oncogenic drivers in non-small-cell lung cancer (NSCLC). We report the results of an updated integrated analysis of three phase I or II clinical trials (ALKA-372-001, STARTRK-1, and STARTRK-2) of the ROS1 tyrosine kinase inhibitor, entrectinib, in ROS1 fusion-positive NSCLC. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/638450 | ISSN: | 0732183X | DOI: | 10.1200/JCO.20.03025 |
顯示於: | 臨床醫學研究所 |
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