https://scholars.lib.ntu.edu.tw/handle/123456789/638571
標題: | Multiphoton polarization and generalized polarization microscopy reveal oleic-acid-induced structural changes in intercellular lipid layers of the skin | 作者: | Sun, Yen Lo, Wen SUNG-JAN LIN SHIOU-HWA JEE CHEN-YUAN DONG |
公開日期: | 1-九月-2004 | 卷: | 29 | 期: | 17 | 來源出版物: | Optics Letters | 摘要: | We have demonstrated that both multiphoton polarization and generalized polarization (GP) microscopy may be combined to characterize the structural changes of intercellular lipids in skin. Both polarization and GP (at 440- and 490-nm emission) images obtained by analysis of Laurdan fluorescence suggest that the treatment of oleic acid results in a skin surface with a more random packing of lipid molecules, which allows easier water penetration. Our results show that combined polarization and GP microscopy can be used to characterize the physical and chemical changes in biological structures. © 2004 Optical Society of America. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/638571 | ISSN: | 01469592 | DOI: | 10.1364/OL.29.002013 |
顯示於: | 醫學工程學研究所 |
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