https://scholars.lib.ntu.edu.tw/handle/123456789/639583
標題: | Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study | 作者: | Mocroft, Amanda Lundgren, Jens D Ross, Michael Law, Matthew Reiss, Peter Kirk, Ole Smith, Colette Wentworth, Deborah Neuhaus, Jacqueline Fux, Christoph A Moranne, Olivier Morlat, Phillipe Johnson, Margaret A Ryom, Lene JOHN TAYU LEE D:A:D study group; Royal Free Hospital Clinic Cohort; INSIGHT study group; SMART study group; ESPRIT study group |
公開日期: | 三月-2015 | 卷: | 12 | 期: | 3 | 來源出版物: | PLoS medicine | 摘要: | Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic antiretrovirals to a treatment regimen and would identify those at greatest risk of CKD. The aims of this study were to develop a simple, externally validated, and widely applicable long-term risk score model for CKD in HIV-positive individuals that can guide decision making in clinical practice. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639583 | ISSN: | 15491277 | DOI: | 10.1371/journal.pmed.1001809 |
顯示於: | 健康政策與管理研究所 |
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