https://scholars.lib.ntu.edu.tw/handle/123456789/639991
標題: | Nickel-Catalyzed Suzuki-Miyaura Coupling in Water for the Synthesis of 2-Aryl Allyl Phosphonates and Sulfones | 作者: | Yu, Yu-Chen Sung, Yun-Chiao Fu, Jun-Hao Peng, Wen-Sheng Yu, Yu-Chia Li, Juyun YI-TSU CHAN Tsai, Fu-Yu |
公開日期: | 16-二月-2024 | 卷: | 89 | 期: | 4 | 起(迄)頁: | 2448 | 來源出版物: | The Journal of organic chemistry | 摘要: | An operationally simple and green protocol using a NiSO4·6H2O/cationic 2,2'-bipyridyl ligand system as a water-soluble catalyst for the coupling of arylboronic acids with (2-haloallyl)phosphonates and (2-haloallyl)sulfones in water under air was developed. The reaction was performed at 120 °C with arylboronic acids (2 mmol) and (2-haloallyl)phosphonates or sulfones (1 mmol) in the presence of 5 mol % of the Ni catalytic system in a basic aqueous solution for 1 h, giving the corresponding 2-aryl allyl phosphonates or sulfones in good to excellent yields. This reaction features the use of an abundant transition metal as a catalyst in water and exhibits high functional group tolerance, rendering it an eco-friendly procedure. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639991 | ISSN: | 00223263 | DOI: | 10.1021/acs.joc.3c02455 |
顯示於: | 化學系 |
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