https://scholars.lib.ntu.edu.tw/handle/123456789/640728
標題: | The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with Brain Ischemia-Reperfusion | 作者: | Chiang, Hui-Ling Wu, Kuo-Chen Chen, You-Yin Ho, Chin-Jui Wang, Han-Lin Fu, Yu-Hua Chen, Wen-Yu CHUN-JUNG LIN |
關鍵字: | adenosine; blood-brain barrier; equilibrative nucleoside transporters; ischemia-reperfusion injury; neuroinflammation | 公開日期: | 十一月-2023 | 卷: | 40 | 期: | 11 | 起(迄)頁: | 2541 | 來源出版物: | Pharmaceutical research | 摘要: | Cerebral vascular protection is critical for stroke treatment. Adenosine modulates vascular flow and exhibits neuroprotective effects, in which brain extracellular concentration of adenosine is dramatically increased during ischemic events and ischemia-reperfusion. Since the equilibrative nucleoside transporter-2 (Ent2) is important in regulating brain adenosine homeostasis, the present study aimed to investigate the role of Ent2 in mice with cerebral ischemia-reperfusion. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/640728 | ISSN: | 07248741 | DOI: | 10.1007/s11095-023-03565-2 |
顯示於: | 藥學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。