https://scholars.lib.ntu.edu.tw/handle/123456789/641363
標題: | Mild cognitive impairment estimation based on functional near-infrared spectroscopy | 作者: | Huang, Yi-Hua Chen, Wei-Yu Liu, Yao-Hong Li, Ting-Ying Lin, Ching-Po Cheong, Pou-Leng Wang, Yi-Min Jeng, Jiann-Shing Sun, Chia-Wei CHAU-CHUNG WU |
關鍵字: | dementia; functional near-infrared spectroscopy; mild cognitive impairment | 公開日期: | 一月-2024 | 出版社: | WILEY-V | 卷: | 17 | 期: | 1 | 來源出版物: | Journal of Biophotonics | 摘要: | Patients with mild cognitive impairment (MCI) are at a high risk of developing future dementia. However, early identification and active intervention could potentially reduce its morbidity and the incidence of dementia. Functional near-infrared spectroscopy (fNIRS) has been proposed as a noninvasive modality for detecting oxygenation changes in the time-varying hemodynamics of the prefrontal cortex. This study sought to provide an effective method for detecting patients with MCI using fNIRS and the Wisconsin card sorting test (WCST) to evaluate changes in blood oxygenation. The results revealed that all groups with a lower mini-mental state examination grade had a higher increase in HHb concentration during a modified WCST (MCST). The increase in the change in oxygenated hemoglobin concentration in the stroke group was smaller than that in the normal group due to weak cerebrovascular reactivity. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641363 | ISSN: | 1864063X | DOI: | 10.1002/jbio.202300251 |
顯示於: | 醫學教育暨生醫倫理學科所 |
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