https://scholars.lib.ntu.edu.tw/handle/123456789/641377
Title: | The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase | Authors: | Yang, Yi-Chieh Lin, Yung-Wei Lee, Wei-Jiunn Lai, Feng-Ru Ho, Kuo-Hao Chu, Chih-Ying KUO-TAI HUA Chen, Ji-Qing Tung, Min-Che Hsiao, Michael Wen, Yu-Ching Chien, Ming-Hsien |
Keywords: | EMT; KSRP; NEDD4L; Progression; ccRCC | Issue Date: | 14-Aug-2023 | Publisher: | BioMed Central Ltd | Journal Volume: | 30 | Journal Issue: | 1 | Source: | Journal of Biomedical Science | Abstract: | KH-type splicing regulatory protein (KHSRP, also called KSRP), a versatile RNA-binding protein, plays a critical role in various physiological and pathological conditions through modulating gene expressions at multiple levels. However, the role of KSRP in clear cell renal cell carcinoma (ccRCC) remains poorly understood. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641377 | ISSN: | 10217770 | DOI: | 10.1186/s12929-023-00949-9 |
Appears in Collections: | 毒理學研究所 |
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