https://scholars.lib.ntu.edu.tw/handle/123456789/641605
標題: | Challenges for hepatitis B control in Asia-Pacific areas: Consolidating vaccination and rolling-out antiviral therapies | 作者: | PEI-JER CHEN | 關鍵字: | SDG; WHO; antiviral; hepatitis B; vaccination | 公開日期: | 27-二月-2024 | 來源出版物: | Journal of gastroenterology and hepatology | 摘要: | Chronic hepatitis B (CHB) was, and still is, a prevalent liver disease in the world, especially high in the Asia-Pacific areas. With the advent of preventive vaccines and effective viral suppression drugs and active implementations, CHB has gradually become under control. The world-wide prevalence reduces from 4.2% in 1980 to 3.2% in 2020 study. CHB patients receiving long-term antiviral therapies significantly improve the clinical outcomes, saving from end-stage liver diseases. Despite of these impressive progresses, to meet the WHO sustained development goals (SDG) for CHB control, a 90% reduction of incidence and a 65% reduction of mortality in year 2030, there is still a long way to go. In this review, four ongoing approaches have been proposed: (i) A continuous monitoring of long-term vaccine efficacy in vaccinated populations; (ii) consolidating the hepatitis B virus vaccination program against vaccine hesitancy and limited resources; (iii) rolling-out current oral antivirals to more CHB patients not only for diseases treatment but also for infection preventions; and (iv) development of curative therapies, both friendly-to-dispense and affordable. A coherent and persevere efforts by the society may succeed and achieve the SDG for CHB in the future. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641605 | ISSN: | 08159319 | DOI: | 10.1111/jgh.16528 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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