https://scholars.lib.ntu.edu.tw/handle/123456789/641621
Title: | High-Throughput Sequencing of Complementarity Determining Region 3 in the Heavy Chain of B-Cell Receptor in Renal Transplant Recipients: A Preliminary Report | Authors: | Wu, Tsai-Hung Liao, Hsien-Tzung Li, Tzu-Hao Tsai, Hung-Cheng Lin, Niang-Cheng Chen, Cheng-Yen Tsai, Shih-Feng Huang, Tzu-Hao Tsai, Chang-Youh CHIA-LI YU |
Keywords: | B cell; clonal diversity; complementary determining region 3 (CDR3); immune repertoire (iR); next-generation sequencing (NGS); renal transplantation | Issue Date: | 25-May-2022 | Publisher: | MDPI | Journal Volume: | 11 | Journal Issue: | 11 | Source: | Journal of clinical medicine | Abstract: | Graft failure resulting from rejection or any other adverse event usually originates from an aberrant and/or exaggerated immune response and is often catastrophic in renal transplantation. So, it is essential to monitor patients' immune status for detecting a rejection/graft failure early on. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641621 | ISSN: | 2077-0383 | DOI: | 10.3390/jcm11112980 |
Appears in Collections: | 分子醫學研究所 |
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