https://scholars.lib.ntu.edu.tw/handle/123456789/83939
標題: | Cerebral columnar organization of the first nociceptive component induced by CO2 laser on the tail of the rat | 作者: | Jaw, F.-S. Kao, Y.-C. Chen, C.-P. Liao, W.-L. JawFS |
關鍵字: | CO2 laser; cortex; current source density; evoked potentials; nociception; rat tail | 公開日期: | 2008 | 起(迄)頁: | - | 來源出版物: | Neuroscience | 摘要: | The somatotopic map of the first nociceptive component in the primary somatosensory cortex (S1) is still unclear. In this study, a CO2 laser was applied to the tail of the rat to induce nociception without the interference from large myelinated (Aβ) fibers. Thus, only noxious fibers could be activated. Two-dimensional current-source-density analysis was used to analyze the evoked field potentials. Using this method, the nociceptive responses of Aδ-fibers in S1 were verified, and the somatotopic map of the first nociceptive component in S1 was identified. We found that whether light touch or laser-induced nociception was applied to the tail of the rat, the responsive topography in S1 was consistent. Discrimination of these two modalities was achieved vertically in the same column; the deeper layer represented the nociceptive response while the superficial layer encoded the response to light touch. This is quite different from that of a primate brain. © 2009 IBRO. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/132112 https://www.scopus.com/inward/record.uri?eid=2-s2.0-58149470569&doi=10.1016%2fj.neuroscience.2008.09.046&partnerID=40&md5=2139b4cb8dda07015412c39721e826f1 |
ISSN: | 03064522 | DOI: | 10.1016/j.neuroscience.2008.09.046 | SDG/關鍵字: | carbon dioxide; afferent nerve group 1; animal experiment; article; brain mapping; controlled study; electric potential; evoked response; laser; male; nerve fiber Adelta; nociception; nonhuman; priority journal; rat; somatosensory cortex; tactile stimulation; Animals; Brain Mapping; Electroencephalography; Evoked Potentials, Somatosensory; Lasers, Gas; Male; Nerve Fibers, Myelinated; Neural Conduction; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Reaction Time; Somatosensory Cortex; Tail |
顯示於: | 醫學工程學研究所 |
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