DC 欄位 | 值 | 語言 |
dc.contributor.author | 丁詩同 | zh_TW |
dc.creator | 丁詩同 | - |
dc.date | 2004 | zh_TW |
dc.date.accessioned | 2006-07-26 | - |
dc.date.accessioned | 2018-06-29T04:16:47Z | - |
dc.date.available | 2006-07-26 | - |
dc.date.available | 2018-06-29T04:16:47Z | - |
dc.date.issued | 2004 | - |
dc.identifier | 922313B002127 | zh_TW |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/16462 | - |
dc.description.abstract | 飼糧中脂肪酸可被動物利用而貯存於
各種組織。許(2002)於飼糧中添加2% 二
十二碳六烯酸DHA 油,顯著增加豬隻各組織
中DHA 之含量,並顯著抑制仔豬肝臟中與脂
質新生合成相關的轉錄因子Sterol Regulatory
Element-Binding Protein-1(SREBP-1) mRNA
的表現。本研究的目的在餵飼豬隻高DHA 或
高硬脂酸飼糧,測試不同脂肪酸組成對豬隻
基因表現的影響。結果發現飼糧中添加2%
DHA 油18 天,顯著增加豬隻各肝臟中DHA
之含量,並顯著增進豬隻肝臟中與脂質氧化
有關基因的表現。利用抑制性雜合扣除法發
現飼糧中添加DHA 可刺激一些與脂質代謝
相關之新穎基因的表現,本計畫亦初步利用
差異篩選法確認12 已知基因和3 個新的基因
表現隨著飼糧中不同的DHA 而有所不同。這
些已知基因包括:alcohol dehydrogenase、
dehydrogenase/reductase (SDR family)
member 8、serum amyloid protein、serine
protease inhibitor I、fibrinogen gamma
polypeptide、vitamin D binding protein、
α1-microglobulin-bikunin precursor 、
glutathione S- transferase、alpha-1 acid
glycoprotein 、X-box binding protein
pseudogene 1、H19 gene 和hypothetical
protein MGC56918。所以餵飼DHA 油除可生
產高DHA 肉品,亦可影響許多肝臟中基因的
表現。 | zh_TW |
dc.format | application/pdf | zh_TW |
dc.format.extent | 178785 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.language | zh-TW | zh_TW |
dc.language.iso | zh_TW | - |
dc.publisher | 臺北市:國立臺灣大學動物科學技術學系暨研究所 | zh_TW |
dc.rights | 國立臺灣大學動物科學技術學系暨研究所 | zh_TW |
dc.subject | 二十二碳六烯酸 | zh_TW |
dc.subject | 抑制性雜合扣除法 | zh_TW |
dc.subject | 基因表現 | zh_TW |
dc.subject | Dietary fatty acid composition can change
fatty acid profiles in several porcine tissues.
Hsu (2002) demonstrated 2% DHA oil in the
diet will significantly increased the DHA in
several porcine tissues. Such changes also
inhibited the expression of hepatic Sterol
Regulatory Element-Binding Protein-1
( SREBP-1 ) mRNA . The purpose of
current project was to test the effect of dietary
high DHA and n-3 PUFA on FA composition
and gene expression in the liver. Dietary DHA
supplementation for 18 d increased the
expression of gene related to FA oxidation. The
suppression subtractive hybridization technique
was used to detect hepatic genes differentially
expressed in the DHA or tallow treated pigs.
A differential screening procedure confirmed
that there were 12 known genes and 3 novel
genes differentially expressed. They were
alcohol dehydrogenase, dehydrogenase/
reductase (SDR family) member 8, serum
amyloid protein, serine protease inhibitor I,
fibrinogen gamma polypeptide, vitamin D
binding protein, α1-microglobulin-bikunin
precursor, glutathione S-transferase, alpha-1
acid glycoprotein, X-box binding protein
pseudogene 1, H19 gene and hypothetical
protein MGC56918. Taken together, dietary
DHA treatment may be used to produce high
DHA meat products and to regulate gene
expression. | en |
dc.title | 飼糧二十二碳六烯酸對豬隻脂質代謝基因表現之影響(2/3) | zh_TW |
dc.type | report | en |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/16462/1/922313B002127.pdf | - |
dc.coverage | 計畫年度:92;起迄日期:2003-08-01/2004-07-31 | zh_TW |
item.openairecristype | http://purl.org/coar/resource_type/c_93fc | - |
item.openairetype | report | - |
item.languageiso639-1 | zh_TW | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.fulltext | with fulltext | - |
crisitem.author.dept | Animal Science and Technology | - |
crisitem.author.dept | Center for Biotechnology | - |
crisitem.author.dept | Office of the Vice President | - |
crisitem.author.orcid | 0000-0002-9866-1776 | - |
crisitem.author.parentorg | College of Bioresources and Agriculture | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | Administrative Unit | - |
顯示於: | 動物科學技術學系
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