公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2014 | Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes | CHIA-RON YANG ; Shih K.-S.; Liou J.-P.; Wu Y.-W.; Hsieh I.-N.; Lee H.-Y.; Lin T.-C.; JYH-HORNG WANG | Journal of Molecular Medicine | 38 | 27 | |
2020 | HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen-glucose deprivation injuries via H3K14 and H4K5 acetylation-mediated BDNF expression | Fang Y.-C.; Chan L.; Liou J.-P.; YONG-KWANG TU ; Lai M.-J.; Chen C.-I.; Vidyanti A.N.; Lee H.-Y.; Hu C.-J. | Journal of Cellular and Molecular Medicine | 12 | 8 | |
2014 | Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity | Mehndiratta S.; Hsieh Y.-L.; Liu Y.-M.; Wang A.W.; Lee H.-Y.; Liang L.-Y.; Kumar S.; Teng C.-M.; CHIA-RON YANG ; Liou J.-P. | European Journal of Medicinal Chemistry | 41 | 39 | |
2013 | Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013) | Lee H.-Y.; CHIA-RON YANG ; Lai M.-J.; Huang H.-L.; Hsieh Y.-L.; Liu Y.-M.; Yeh T.-K.; Li Y.-H.; Mehndiratta S.; Teng C.-M.; Liou J.-P. | ChemBioChem | 0 | 0 | |
2014 | Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2 | Hou P.; CHING-YING KUO ; Cheng C.-T.; Liou J.-P.; Ann D.K.; Chen Q. | PLoS ONE | 28 | 26 | |
2019 | MPT0G413, A novel HDAC6-selective inhibitor, and bortezomib synergistically exert anti-tumor activity in multiple myeloma cells | Huang F.-I.; Wu Y.-W.; Sung T.-Y.; Liou J.-P.; Lin M.-H.; Pan S.-L.; CHIA-RON YANG | Frontiers in Oncology | 19 | 18 | |
2018 | (N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo | Lee H.-Y.; Nepali K.; Huang F.-I.; Chang C.-Y.; Lai M.-J.; Li Y.-H.; Huang H.-L.; CHIA-RON YANG ; Liou J.-P. | Journal of Medicinal Chemistry | 63 | 60 | |
2021 | A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo | Wu Y.-W.; Chao M.-W.; Tu H.-J.; Chen L.-C.; Hsu K.-C.; Liou J.-P.; CHIA-RON YANG ; Yen S.-C.; HuangFu W.-C.; Pan S.-L. | Oncogenesis | 15 | 16 | |
2018 | The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model article | Fan S.-J.; Huang F.-I.; Liou J.-P.; CHIA-RON YANG | Cell Death and Disease | 66 | 64 | |
2016 | Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma | Chen M.-C.; Huang H.-H.; Lai C.-Y.; Lin Y.-J.; Liou J.-P.; Lai M.-J.; Li Y.-H.; Teng C.-M.; CHIA-RON YANG | Oncotarget | 20 | 20 | |
1996 | Novel radical synthesis of morphine fragments spiro[benzofuran-3(2H),4'-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline | Cheng C.-Y.; LING-WEI HSIN ; Liou J.-P. | Tetrahedron | 24 | 21 | |
2021 | Optimization and development of selective histone deacetylase inhibitor (Mpt0b291)-loaded albumin nanoparticles for anticancer therapy | Putri A.D.; PAI-SHAN CHEN ; Su Y.-L.; Lin J.-P.; Liou J.-P.; Hsieh C.-M. | Pharmaceutics | 7 | 7 | |
2014 | Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009 | Hsieh I.-N.; Liou J.-P.; Lee H.-Y.; Lai M.-J.; Li Y.-H.; CHIA-RON YANG | Cell Death and Disease | 30 | 29 | |
2020 | Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment | Kaur N.; Fang Y.-C.; Lee H.-Y.; Singh A.; Nepali K.; Lin M.-H.; Yeh T.-K.; Lai M.-J.; Chan L.; YONG-KWANG TU ; Banerjee S.; Hu C.-J.; Liou J.-P. | European Journal of Medicinal Chemistry | 13 | 10 | |