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  1. NTU Scholars
  2. Research Outputs

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Showing results 1 to 20 of 74  next >
Issue DateTitleAuthor(s)SourcescopusWOSFulltext/Archive link
20022,3-Dimethoxybenzo[i]phenanthridines: Topoisomerase I-targeting anticancer agentsLi D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J.Bioorganic and Medicinal Chemistry5051
20035H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activityRuchelman A.L.; Singh S.K.; Ray A.; Wu X.H.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J.Bioorganic and Medicinal Chemistry107106
20038,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicityLi D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J.Bioorganic and Medicinal Chemistry3738
2003Acidic pH induces topoisomerase II-mediated DNA damageXiao H.; TSAI-KUN LI ; Yang J.-M.; Liu L.F.Proceedings of the National Academy of Sciences of the United States of America6553
2022Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicityYeh Y.-H.; Tsai C.-C.; Chen T.-W.; Lee C.-H.; Chang W.-J.; Hsieh M.-Y.; TSAI-KUN LI Molecular and Cellular Biochemistry11
1999Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stressTSAI-KUN LI ; Chen A.Y.; Yu C.; Mao Y.; Wang H.; Liu L.F.Genes and Development148136
2003Aminoglycoside complexation with a DNA·RNA hybrid duplex: The thermodynamics of recognition and inhibition of RNA processing enzymesBarbieri C.M.; TSAI-KUN LI ; Guo S.; Wang G.; Shallop A.J.; Pan W.; Yang G.; Gaffney B.L.; Jones R.A.; Pilch D.S.Journal of the American Chemical Society2927
2012Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profilesLee C.-H.; Hsieh M.-Y.; LING-WEI HSIN ; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; NEI-LI CHAN ; TSAI-KUN LI Biochemical Pharmacology1212
2003Aza-analogs of dibenzo[c,h]cinnoline: Triazachrysenes as potent topoisomerase I-targeting anticancer agentsSingh S.K.; Ruchelman A.L.; Zhou N.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J.Medicinal Chemistry Research8
2011Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI Cellular and Molecular Life Sciences98
2000The camptothecins: Unfolding their anticancer potential: IntroductionLiu L.F.; Desai S.D.; TSAI-KUN LI ; Yong M.A.O.; Sun M.E.I.; Sai-Peng S.I.M.Annals of the New York Academy of Sciences1
2012Cell type-specific effects of Adenosine 5′-triphosphate and pyrophosphate on the antitumor activity of doxorubicinWang J.-S.; Chang Y.-L.; Yu Y.-H.; Chen C.-Y.; Kao M.-C.; TSAI-KUN LI ; WAN-WAN LIN Cancer Science44
2010Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakageHuang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI Cell Research1311
2008Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responsesFan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI DNA Repair4441
1996Cellular resistance to topoisomerase poisons.Rubin E.H.; TSAI-KUN LI ; Duann P.; Liu L.F.Cancer treatment and research360
2003Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer DrugTSAI-KUN LI ; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F.Cancer Research9795
2007Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replicationLu C.-C.; Huang H.-T.; Wang J.-T.; Slupphaug G.; TSAI-KUN LI ; Wu M.-C.; Chen Y.-C.; Lee C.-P.; Chen M.-R.Journal of Virology2627
2020Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerasesLee J.-F.; Chang T.-Y.; Liu Z.-F.; Lee N.-Z.; Yeh Y.-H.; Chen Y.-S.; Chen T.-C.; Chou H.-S.; TSAI-KUN LI ; Lee S.-B.; Lin M.-H.European Journal of Medicinal Chemistry78
2002Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J.Bioorganic and Medicinal Chemistry Letters5655
1997Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugarSim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI ; Pilch D.S.; LaVoie E.J.; Liu L.F.Biochemistry3836
Showing results 1 to 20 of 74  next >

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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  • 網站簡介 (Quickstart Guide)
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  • 方案一:臺灣大學計算機中心帳號登入
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  • 方案二:ORCID帳號登入 (With ORCID)
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  • 方案二:自行建檔 (Default mode Submission)
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