公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2020 | Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases | Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; TSAI-KUN LI ; Lee, Sung-Bau; Lin, Mei-Hsiang | European Journal of Medicinal Chemistry | 10 | 9 | |
2002 | Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435 | Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry Letters | 56 | 56 | |
1997 | Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar | Sim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI ; Pilch D.S.; LaVoie E.J.; Liu L.F. | Biochemistry | 39 | 36 | |
2009 | Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification | You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI ; Chern J.-W. | Journal of Medicinal Chemistry | 91 | 71 | |
2006 | Distribution of gyrase and topoisomerase IV on bacterial nucleoid: Implications for nucleoid organization | Hsu Y.-H.; Chung M.-W.; TSAI-KUN LI | Nucleic Acids Research | 30 | 28 | |
2003 | DNA damage-mediated apoptosis induced by selenium compounds | Zhou N.; Xiao H.; TSAI-KUN LI ; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 135 | 128 | |
1998 | DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles | Xu Z.; TSAI-KUN LI ; Kim J.S.; LaVoie E.J.; Breslauer K.J.; Liu L.F.; Pilch D.S. | Biochemistry | 39 | 39 | |
2013 | DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia | Lin B.-C.; Su L.-H.; Weng S.-C.; Pan Y.-J.; NEI-LI CHAN ; TSAI-KUN LI ; Wang H.-C.; CHIN-HUNG SUN | PLoS Neglected Tropical Diseases | 11 | 9 | |
2014 | DNA topoisomerase III alpha regulates P53-mediated tumor suppression | Hsieh, Mei-Yi; Fan, Jia-Rong; Chang, Han-Wen; Chen, Hsiang-Chin; TANG-LONG SHEN ; SHU-CHUN TENG ; Yeh, Yen-Hsiu; TSAI-KUN LI | Clinical Cancer Research | 10 | 8 | |
2009 | Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism | Tai C.C.; Chen C.Y.; Lee, Hsuan-Shu ; Wang Y.C.; TSAI-KUN LI ; Mersamm H.J.; Ding S.T.; PEI-HWA WANG | Journal of Biological Chemistry | 22 | 22 | |
2012 | Docosahexaenoic acid suppresses the expression of FoxO and its target genes | Chen Y.-J.; Chen C.-C.; TSAI-KUN LI ; Wang P.-H.; Liu L.-R.; Chang F.-Y.; Wang Y.-C.; Yu Y.-H.; Lin S.-P.; Mersmann H.J.; PEI-HWA WANG | Journal of Nutritional Biochemistry | 41 | 39 | |
2004 | Drug targeting of HIV-1 RNA·DNA hybrid structures: Thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication | TSAI-KUN LI ; Barbieri C.M.; Lin H.-C.; Rabson A.B.; Yang G.; Fan Y.; Gaffney B.L.; Jones R.A.; Pilch D.S. | Biochemistry | 19 | 18 | |
2010 | EGF-induced Grb7 recruits and promotes ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells | Chu P.-Y.; TSAI-KUN LI ; Ding S.-T.; I-RUE LAI ; Shen T.-L. | Journal of Biological Chemistry | 39 | 38 | |
2015 | Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential | Wang Y.-W.; Hong T.-W.; Tai Y.-L.; Wang Y.-J.; Tsai S.-H.; Lien P.T.K.; Chou T.-H.; Lai J.-Y.; Chu R.; Ding S.-T.; Irie K.; TSAI-KUN LI ; Tzean S.-S.; Shen T.-L. | Evidence-based Complementary and Alternative Medicine | 11 | 6 | |
2007 | Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult | Yeh T.-C.; Chiang P.-C.; TSAI-KUN LI ; Hsu J.-L.; CHUN-JUNG LIN ; Wang S.-W.; Peng C.-Y.; JIH-HWA GUH | Biochemical Pharmacology | 123 | 110 | |
2000 | Human topoisomerase I poisoning by protoberberines: Potential roles for both drug-DNA and drug-enzyme interactions | TSAI-KUN LI ; Bathory E.; LaVoie E.J.; Srinivasan A.R.; Olson W.K.; Sauers R.R.; Liu L.F.; Pilch D.S. | Biochemistry | 97 | 84 | |
2004 | Hydrogen Peroxide Induces Topoisomerase I-mediated DNA Damage and Cell Death | Daroui P.; Desai S.D.; TSAI-KUN LI ; Liu A.A.; Liu L.F. | Journal of Biological Chemistry | 118 | 112 | |
2003 | Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast | Qi H.; TSAI-KUN LI ; Kuo D.; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 56 | 55 | |
1997 | Incompatibility of Escherichia coli rho mutants with plasmids is mediated by plasmid-specific transcription | TSAI-KUN LI ; Panchenko Y.A.; Drolet M.; Liu L.F. | Journal of Bacteriology | 4 | 4 | |
2006 | Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells | Chiang P.-C.; FAN-LU KUNG ; Huang D.-M.; TSAI-KUN LI ; Fan J.-R.; Pan S.-L.; Shen Y.-C.; JIH-HWA GUH | European Journal of Pharmacology | 23 | 24 | |