公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2011 | Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2 | Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI | Cellular and Molecular Life Sciences | 9 | 8 | |
2000 | The camptothecins: Unfolding their anticancer potential: Introduction | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Yong M.A.O.; Sun M.E.I.; Sai-Peng S.I.M. | Annals of the New York Academy of Sciences | 1 | | |
2012 | Cell type-specific effects of Adenosine 5′-triphosphate and pyrophosphate on the antitumor activity of doxorubicin | Wang J.-S.; Chang Y.-L.; Yu Y.-H.; Chen C.-Y.; Kao M.-C.; TSAI-KUN LI ; WAN-WAN LIN | Cancer Science | 5 | 5 | |
2010 | Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage | Huang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI | Cell Research | 13 | 12 | |
2008 | Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses | Fan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI | DNA Repair | 47 | 43 | |
1996 | Cellular resistance to topoisomerase poisons. | Rubin E.H.; TSAI-KUN LI ; Duann P.; Liu L.F. | Cancer treatment and research | 37 | 0 | |
2003 | Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer Drug | TSAI-KUN LI ; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F. | Cancer Research | 101 | 97 | |
2007 | Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication | Lu C.-C.; Huang H.-T.; Wang J.-T.; Slupphaug G.; TSAI-KUN LI ; Wu M.-C.; Chen Y.-C.; Lee C.-P.; MEI-RU CHEN | Journal of Virology | 30 | 29 | |
2020 | Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases | Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; TSAI-KUN LI ; Lee, Sung-Bau; Lin, Mei-Hsiang | European Journal of Medicinal Chemistry | 10 | 9 | |
2002 | Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435 | Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry Letters | 56 | 56 | |
1997 | Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar | Sim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI ; Pilch D.S.; LaVoie E.J.; Liu L.F. | Biochemistry | 39 | 36 | |
2009 | Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification | You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI ; Chern J.-W. | Journal of Medicinal Chemistry | 91 | 71 | |
2006 | Distribution of gyrase and topoisomerase IV on bacterial nucleoid: Implications for nucleoid organization | Hsu Y.-H.; Chung M.-W.; TSAI-KUN LI | Nucleic Acids Research | 30 | 28 | |
2003 | DNA damage-mediated apoptosis induced by selenium compounds | Zhou N.; Xiao H.; TSAI-KUN LI ; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 135 | 128 | |
1998 | DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles | Xu Z.; TSAI-KUN LI ; Kim J.S.; LaVoie E.J.; Breslauer K.J.; Liu L.F.; Pilch D.S. | Biochemistry | 39 | 39 | |
2013 | DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia | Lin B.-C.; Su L.-H.; Weng S.-C.; Pan Y.-J.; NEI-LI CHAN ; TSAI-KUN LI ; Wang H.-C.; CHIN-HUNG SUN | PLoS Neglected Tropical Diseases | 11 | 9 | |
2014 | DNA topoisomerase III alpha regulates P53-mediated tumor suppression | Hsieh, Mei-Yi; Fan, Jia-Rong; Chang, Han-Wen; Chen, Hsiang-Chin; TANG-LONG SHEN ; SHU-CHUN TENG ; Yeh, Yen-Hsiu; TSAI-KUN LI | Clinical Cancer Research | 10 | 8 | |
2009 | Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism | Tai C.C.; Chen C.Y.; Lee, Hsuan-Shu ; Wang Y.C.; TSAI-KUN LI ; Mersamm H.J.; Ding S.T.; PEI-HWA WANG | Journal of Biological Chemistry | 22 | 22 | |
2012 | Docosahexaenoic acid suppresses the expression of FoxO and its target genes | Chen Y.-J.; Chen C.-C.; TSAI-KUN LI ; Wang P.-H.; Liu L.-R.; Chang F.-Y.; Wang Y.-C.; Yu Y.-H.; Lin S.-P.; Mersmann H.J.; PEI-HWA WANG | Journal of Nutritional Biochemistry | 41 | 39 | |
2004 | Drug targeting of HIV-1 RNA·DNA hybrid structures: Thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication | TSAI-KUN LI ; Barbieri C.M.; Lin H.-C.; Rabson A.B.; Yang G.; Fan Y.; Gaffney B.L.; Jones R.A.; Pilch D.S. | Biochemistry | 19 | 18 | |