公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2000 | Mechanism of action of camptothecin | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Mao Y.; Sun M.; Sim S.-P. | Annals of the New York Academy of Sciences | 449 | 390 | |
2017 | MicroRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1 | Lin H.-C.; Liu S.-Y.; Yen E.-Y.; TSAI-KUN LI ; I-RUE LAI | Antioxidants and Redox Signaling | 11 | 10 | |
2011 | Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway | Toh Y.-M.; TSAI-KUN LI | Clinical Cancer Research | 27 | 27 | |
1998 | Modulation of gyrase-mediated DNA cleavage and cell killing by ATP | TSAI-KUN LI ; Liu L.F. | Antimicrobial Agents and Chemotherapy | 18 | 18 | |
2012 | Multiple domains of the Tobacco mosaic virus p126 protein can independently suppress local and systemic RNA silencing | Wang L.-Y.; Lin S.-S.; Hung T.-H.; TSAI-KUN LI ; Lin N.-C.; NAI-CHUN LIN ; SHIH-SHUN LIN | Molecular Plant-Microbe Interactions | 48 | 45 | |
2013 | A negative feedback of the HIF-1α pathway via interferon-stimulated gene 15 and ISGylation | Yeh Y.-H.; Yang Y.-C.; Hsieh M.-Y.; Yeh Y.-C.; TSAI-KUN LI | Clinical Cancer Research | 30 | 25 | |
2003 | Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)2,3-methylenedioxy-5H-dibenzo[c,h][1,6] naphthyridin-6-ones: Effect on topoisomerase-I targeting activity and cytotoxicity | Singh S.K.; Ruchelman A.L.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Journal of Medicinal Chemistry | 51 | 47 | |
2004 | Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N, N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Influence on topoisomerase I-targeting activity and cytotoxicity | Ruchelman A.L.; Kerrigan J.E.; TSAI-KUN LI ; Zhou N.; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 31 | 31 | |
2014 | A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i | Yu C.-C.; Pan S.-L.; Chao S.-W.; SHIH-PING LIU ; Hsu J.-L.; Yang Y.-C.; TSAI-KUN LI ; Huang W.-J.; JIH-HWA GUH | Biochemical Pharmacology | 29 | 28 | |
2013 | On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs | Wu C.-C.; Li Y.-C.; Wang Y.-R.; TSAI-KUN LI ; NEI-LI CHAN | Nucleic Acids Research | 137 | 134 | |
2019 | The paracrine induction of prostate cancer progression by caveolin-1 | Lin, C.-J.; Yun, E.-J.; Lo, U.-G.; Tai, Y.-L.; Deng, S.; Hernandez, E.; Dang, A.; Chen, Y.-A.; Saha, D.; Mu, P.; Lin, H.; TSAI-KUN LI ; Shen, T.-L.; Lai, C.-H.; TANG-LONG SHEN | Cell Death and Disease | 39 | 37 | |
2007 | Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycle | Lin S.-C.; SHIH-CHIEH CHUEH ; Hsiao C.-J.; TSAI-KUN LI ; Chen T.-H.; Liao C.-H.; Lyu P.-C.; JIH-HWA GUH | Neoplasia | 61 | 58 | |
2017 | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry | Wang Y.-R.; Chen S.-F.; Wu C.-C.; Liao Y.-W.; Lin T.-S.; Liu K.-T.; Chen Y.-S.; TSAI-KUN LI ; Chien T.-C.; NEI-LI CHAN | Nucleic Acids Research | 60 | 60 | |
2022 | Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells | Costanzo, Federico; Martínez Diez, Marta; Santamaría Nuñez, Gema; Díaz-Hernandéz, Juan Ignacio; Genes Robles, Carlos Mario; Díez Pérez, Javier; Compe, Emmanuel; Ricci, Romeo; TSAI-KUN LI ; Coin, Frédéric; Martínez Leal, Juan Fernando; Garrido-Martin, Eva Maria; Egly, Jean Marc | EMBO molecular medicine | 13 | | |
2012 | QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells | Chen M.-C.; Pan S.-L.; Shi Q.; Xiao Z.; Lee K.-H.; TSAI-KUN LI ; Teng C.-M. | Cancer Science | 15 | 13 | |
2018 | Regioselective synthesis and biological evaluation of: N -substituted 2-aminoquinazolin-4-ones | Liao Z.-Y.; Yeh W.-H.; Liao P.-Y.; Liu Y.-T.; Chen Y.-C.; Chen Y.-H.; Hsieh T.-H.; Lin C.-C.; Lu M.-H.; Chen Y.-S.; Hsu M.-C.; TSAI-KUN LI ; Chien T.-C. | Organic and Biomolecular Chemistry | 13 | 13 | |
2020 | Retraction notice to "Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases" [Eur. J. Med. Chem. 190 (2020) 112074] | Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; TSAI-KUN LI ; Lee, Sung-Bau; Lin, Mei-Hsiang | European journal of medicinal chemistry | 0 | 0 | |
2016 | Rhapontigenin inhibits TGF-β-mediated epithelial-mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation | Yeh Y.-H.; Wang S.-W.; Yeh Y.-C.; Hsiao H.-F.; TSAI-KUN LI | Oncology Reports | 18 | 20 | |
2020 | The role of extracellular vesicles in prostate cancer with clinical applications | Tai, Y.-L.; Lin, C.-J.; TSAI-KUN LI ; Shen, T.-L.; Hsieh, J.-T.; TANG-LONG SHEN | Endocrine-Related Cancer | 12 | 11 | |
2012 | Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway | Hsu J.-L.; Ho Y.-F.; TSAI-KUN LI ; Chen C.-S.; LIH-CHING HSU ; JIH-HWA GUH | Biochemical Pharmacology | 18 | 16 | |