公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2020 | Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase–negative cells | Zencir S.; Hsieh M.-H.; Hsu J.-S.; Ergun Y.; Chou G.-L.; TSAI-KUN LI ; Teng S.-C.; Topcu Z. | Journal of Cancer Research and Clinical Oncology | 3 | 3 | |
1998 | Selective cytotoxicity of topoisomerase-directed protoberberines against glioblastoma cells | Sanders M.M.; Liu A.A.; TSAI-KUN LI ; Wu H.-Y.; Desai S.D.; Mao Y.; Rubin E.H.; LaVoie E.J.; Makhey D.; Liu L.F. | Biochemical Pharmacology | 55 | 52 | |
2003 | Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals | Nur-E-Kamal A.; TSAI-KUN LI ; Zhang A.; Qi H.; Hars E.S.; Liu L.F. | Journal of Biological Chemistry | 47 | 43 | |
2010 | Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses | Fan J.-R.; Huang T.-H.; Wen C.-Y.; Shen T.-L.; TSAI-KUN LI | European Journal of Pharmacology | 4 | 4 | |
2011 | Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide | Wu C.-C.; TSAI-KUN LI ; Farh L.; Lin L.-Y.; Lin T.-S.; Yu Y.-J.; Yen T.-J.; Chiang C.-W.; NEI-LI CHAN | Science | 388 | 380 | |
2003 | Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents | Makhey D.; Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 45 | 45 | |
2003 | Substituted dibenzo[c,h]cinnolines: Topoisomerase I-targeting anticancer agents | Yu Y.; Singh S.K.; Liu A.; TSAI-KUN LI ; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 95 | 92 | |
2014 | Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells | Chou S.-M.; Lai W.-J.; Hong T.-W.; Lai J.-Y.; Tsai S.-H.; Chen Y.-H.; Yu S.-H.; Kao C.-H.; Chu R.; Ding S.-T.; TSAI-KUN LI ; Shen T.-L. | Phytomedicine | 36 | 27 | |
2008 | Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates | LING-WEI HSIN ; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; JIH-HWA GUH ; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI ; Lee C.-H. | Bioorganic and Medicinal Chemistry | 45 | 41 | |
2015 | Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers | Hsieh M.-H.; Tsai C.-H.; Hung J.-J.; TSAI-KUN LI ; SHU-CHUN TENG ; Chang L.-T.; LING-WEI HSIN ; Teng S.-C. | Cellular and Molecular Life Sciences | 8 | 9 | |
2013 | Topoisomerase II-mediated DNA cleavage and mutagenesis activated by nitric oxide underlie the inflammation-associated tumorigenesis | Yang Y.-C.; HAN-YI E. CHOU ; Shen T.-L.; Chang W.-J.; Tai P.-H.; TSAI-KUN LI | Antioxidants and Redox Signaling | 19 | 18 | |
2017 | Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts | Chien, M.-H.; Lee T.-H.; Lee W.-J.; Yeh Y.-H.; TSAI-KUN LI ; Wang P.-C.; Chen J.-J.; Chow J.-M.; Lin Y.-W.; Hsiao M.; Wang S.-W.; TZONG-HUEI LEE et al. | Cancer Letters | 14 | 12 | |
2001 | Tumor cell death induced by topoisomerase-targeting drugs | TSAI-KUN LI ; Liu L.F. | Annual review of Pharmacology and Toxicology | 481 | 450 | |
2000 | Ubiquitin, SUMO-1, and UCRP in camptothesin sensitivity and resistance | Desai S.D.; Yong M.A.O.; Sun M.E.I.; TSAI-KUN LI ; Jiaxi W.U.; Liu L.F.; New Jersey | Annals of the New York Academy of Sciences | 24 | 21 | |
2001 | Ubiquitin/26s proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells | Desai S.D.; TSAI-KUN LI ; Rodriguez-Bauman A.; Liu L.F.; Rubin E.H. | Cancer Research | 196 | 191 | |
2008 | WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers | Hsiao C.-J.; TSAI-KUN LI ; Chan Y.-L.; LING-WEI HSIN ; Liao C.-H.; Lee C.-H.; Lyu P.-C.; JIH-HWA GUH | Biochemical Pharmacology | 35 | 32 | |