公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
1992 | Selective Reversible and Irreversible Ligands for the k Opioid Receptor | Cheng C.-Y.; Shou-Chien W.; LING-WEI HSIN ; Tam S.W. | Journal of Medicinal Chemistry | 22 | 20 | |
2005 | Stereoselective synthesis of morphine fragments trans- and cis-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolines | LING-WEI HSIN ; Chang L.-T.; Chen C.-W.; Hsu C.-H.; Chen H.-W. | Tetrahedron | 15 | 14 | |
2020 | Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[18F]fluoropropyl)-L-glutamic acid ([18F]FSPG) for clinical use | Shih, Kai-Ting; Huang, Ya-Yao; Yang, Chia-Ying; MEI-FANG CHENG ; YU-WEN TIEN ; Shiue, Chyng-Yann; RUOH-FANG YEN ; LING-WEI HSIN | PloS one | 4 | 4 | |
2000 | Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: The development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor | LING-WEI HSIN ; Webster E.L.; Chrousos G.P.; Gold P.W.; Eckelman W.C.; Contoreggi C.; Rice K.C. | Bioorganic and Medicinal Chemistry Letters | 22 | 21 | |
2023 | Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities | Chu, Jung-Chun; Tseng, Hui-Ju; Lee, Sung-Bau; Hsu, Kai-Cheng; LING-WEI HSIN ; Liang, Ru-Hao; Lin, Tony Eight; Gao, Nain-Chu; Chen, Liang-Chieh; Lu, Wan-Hsun; Wang, Andrew H-J; Huang, Wei-Jan | Journal of enzyme inhibition and medicinal chemistry | | | |
2021 | Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors | Hsu K.-C.; Chu J.-C.; Tseng H.-J.; Liu C.-I.; Wang H.-C.; Lin T.E.; Lee H.-S.; LING-WEI HSIN ; Wang A.H.-J.; Lin C.-H.; Huang W.-J. | European Journal of Medicinal Chemistry | 9 | 6 | |
2003 | Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents | LING-WEI HSIN ; Prisinzano T.; Wilkerson C.R.; Dersch C.M.; Horel R.; Jacobson A.E.; Rothman R.B.; Rice K.C. | Bioorganic and Medicinal Chemistry Letters | 16 | 14 | |
2020 | Synthesis and evaluation of 2-(2′-((dimethylamino)methyl)-4′-(2-fluoroethoxy-substituted)phenylthio)benzenamine derivatives as potential positron emission tomography imaging agents for serotonin transporters | Huang Y.-Y.; Chang L.-T.; Shen H.-Y.; Chen Y.-H.; KAI-YUAN TZEN ; Shiue C.-Y.; LING-WEI HSIN | Bioorganic Chemistry | 0 | 0 | |
1994 | Synthesis and Opioid Activity of 7-Oxygenated 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolin-9-ols | Cheng C.-Y.; LING-WEI HSIN ; Tsai M.-C.; Schmidt W.K.; Smith C.; Tam S.W. | Journal of Medicinal Chemistry | 13 | 12 | |
2010 | Synthesis and opioid activity of enantiomeric N-substituted 2,3,4,4a,5,6,7, 7a-octahydro-1H-benzofuro[3,2-e]isoquinolines | LING-WEI HSIN ; Chang L.-T.; Rothman R.B.; Dersch C.M.; Fishback J.A.; Matsumoto R.R. | Journal of Medicinal Chemistry | 12 | 11 | |
1996 | Synthesis of 1,4-bis [(17-normorphinyl)methyl]cubane, a morphine dimer linked by cubane | Cheng C.-Y.; LING-WEI HSIN ; Tao P.-L. | Chinese Pharmaceutical Journal | 0 | | |
2002 | Synthesis of 1,4-dihydro-2-phenyl-4,4-bis(4-pyridinylmethyl)-2H-isoquinolin-3-one and related compounds as acetylcholine release enhancers | Lin M.-S.; LING-WEI HSIN ; Tsai H.-B.; Tsai M.-C.; Cheng C.-Y. | Chinese Pharmaceutical Journal | 2 | | |
2004 | Synthesis of 3-[4-acyl-2-(1-methoxy-1-methylethyl)morpholin-3-yl]- benzonitriles as novel potassium channel openers | Lin M.-S.; LING-WEI HSIN ; Cheng C.-Y. | Journal of the Chinese Chemical Society | 0 | 2 | |
2000 | Synthesis of [3H](4-fluorobutyl)propyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amine: A potent radioligand for corticotropin-releasing hormone type 1 receptor | LING-WEI HSIN ; Webster E.L.; Chrousos G.P.; Gold P.W.; Eckelman W.C.; Contoreggi C.; Rice K.C. | Journal of Labelled Compounds and Radiopharmaceuticals | 12 | | |
2003 | Synthesis of galanthamine analogs as acetylcholinesterase inhibitors via intramolecular heck cvclization | PI-HUI LIANG ; LING-WEI HSIN ; Pong S.-L.; Hsu C.-H.; Cheng C.-Y. | Journal of the Chinese Chemical Society | 12 | 12 | |
2008 | Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates | LING-WEI HSIN ; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; JIH-HWA GUH ; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI ; Lee C.-H. | Bioorganic and Medicinal Chemistry | 45 | 41 | |
2017 | Targeting breast cancer stem cells by novel HDAC3-selective inhibitors | Hsieh H.-Y.; Chuang H.-C.; Shen F.-H.; Detroja K.; LING-WEI HSIN ; Chen C.-S. | European Journal of Medicinal Chemistry | 54 | 51 | |
2015 | Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers | Hsieh M.-H.; Tsai C.-H.; Hung J.-J.; TSAI-KUN LI ; SHU-CHUN TENG ; Chang L.-T.; LING-WEI HSIN ; Teng S.-C. | Cellular and Molecular Life Sciences | 8 | 9 | |
2008 | WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers | Hsiao C.-J.; TSAI-KUN LI ; Chan Y.-L.; LING-WEI HSIN ; Liao C.-H.; Lee C.-H.; Lyu P.-C.; JIH-HWA GUH | Biochemical Pharmacology | 35 | 32 | |