公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2017 | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry | Wang Y.-R.; Chen S.-F.; Wu C.-C.; Liao Y.-W.; Lin T.-S.; Liu K.-T.; Chen Y.-S.; TSAI-KUN LI ; Chien T.-C.; NEI-LI CHAN | Nucleic Acids Research | 60 | 60 | |
2022 | Sequential Phosphorylation of Hepatitis C Virus NS5A Protein Requires the ATP-Binding Domain of NS3 Helicase | Yu, Chun-Chiao; Lin, Pei-Chen; Chiang, Cho-Han; Jen, Shu-Tang; Lai, Yen-Ling; Hsu, Shih-Chin; Lo, Lee-Chiang; JING-JER LIN ; NEI-LI CHAN ; MING-JIUN YU | Journal of virology | 2 | 2 | |
2016 | SMYD3-mediated H2A.Z.1 methylation promotes cell cycle and cancer proliferation | Tsai C.-H.; Chen Y.-J.; Hung J.-J.; SHIOU-RU TZENG ; Chen W.-Y.; WEN-HUNG KUO ; Lin M.-C.; NEI-LI CHAN ; Chen Y.-J.; Cheng W.-C.; SHU-CHUN TENG ; Wu K.-J. | Cancer Research | 42 | 41 | |
2016 | Strong inhibition of betanodavirus replication by ribavirin targeting RNA-dependent RNA polymerase | Huang Y.-C.; Lin T.-S.; Peng C.; NEI-LI CHAN ; YU-SAN HAN | Journal of Fish Diseases | 12 | 11 | |
2016 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity | Lee Y.-R.; Lin T.-S.; Lai S.-J.; Liu M.-S.; Lai M.-C.; NEI-LI CHAN | Scientific Reports | 3 | 3 | |
2015 | Structural basis of antizyme-mediated regulation of polyamine homeostasis | Wu H.-Y.; Chen S.-F.; Hsieh J.-Y.; Chou F.; Wang Y.-H.; Lin W.-T.; Lee P.-Y.; Yu Y.-J.; Lin L.-Y.; Lin T.-S.; Lin C.-L.; Liu G.-Y.; SHIOU-RU TZENG ; Hung H.-C.; NEI-LI CHAN | Proceedings of the National Academy of Sciences of the United States of America | 55 | 53 | |
2015 | Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR | Chang C.-C.; Lin L.-Y.; Zou X.-W.; Huang C.-C.; NEI-LI CHAN | Nucleic Acids Research | 53 | 51 | |
2011 | Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide | Wu C.-C.; TSAI-KUN LI ; Farh L.; Lin L.-Y.; Lin T.-S.; Yu Y.-J.; Yen T.-J.; Chiang C.-W.; NEI-LI CHAN | Science | 388 | 380 | |
2014 | Structural characteristics of the nonallosteric human cytosolic malic enzyme | Hsieh J.-Y.; Li S.-Y.; Chen M.-C.; Yang P.-C.; Chen H.-Y.; NEI-LI CHAN ; Liu J.-H.; Hung H.-C. | Biochimica et Biophysica Acta - Proteins and Proteomics | 16 | 16 | |
2018 | Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate | Chen S.-F.; Huang N.-L.; Lin J.-H.; Wu C.-C.; Wang Y.-R.; Yu Y.-J.; Gilson M.K.; NEI-LI CHAN | Nature Communications | 37 | 36 | |
2005 | Structure and function of the XpsE N-terminal domain, an essential component of the Xanthomonas campestris type II secretion system | Chen Y.; Shiue S.-J.; Huang C.-W.; Chang J.-L.; Chien Y.-L.; Hu N.-T.; NEI-LI CHAN | Journal of Biological Chemistry | 32 | 32 | |
2020 | Structure of Human Phosphodiesterase 5A1 Complexed with Avanafil Reveals Molecular Basis of Isoform Selectivity and Guidelines for Targeting α-Helix Backbone Oxygen by Halogen Bonding | Hsieh, Chao-Ming; Chen, Chun-Yi; JI-WANG CHERN ; NEI-LI CHAN | Journal of medicinal chemistry | 9 | 6 | |
2004 | Structure of the topoisomerase IV C-terminal domain: A broken β-propeller implies a role as geometry facilitator in catalysis | Hsieh T.-J.; Farh L.; Huang W.M.; NEI-LI CHAN | Journal of Biological Chemistry | 43 | 42 | |
2008 | Structures of prostacyclin synthase and its complexes with substrate analog and inhibitor reveal a ligand-specific heme conformation change | Li Y.-C.; Chiang C.-W.; Yeh H.-C.; Hsu P.-Y.; Whitby F.G.; Wang L.-H.; NEI-LI CHAN | Journal of Biological Chemistry | 46 | 41 | |
2018 | Topoisomerases as anticancer targets | Delgado J.L.; Hsieh C.-M.; NEI-LI CHAN ; Hiasa H. | Biochemical Journal | 264 | 252 | |
2010 | Twisting of the DNA-binding surface by a β-strand-bearing proline modulates DNA gyrase activity | Hsieh T.-J.; Yen T.-J.; Lin T.-S.; Chang H.-T.; Huang S.-Y.; Hsu C.-H.; Farh L.; NEI-LI CHAN | Nucleic Acids Research | 26 | 23 | |
2006 | XpsE oligomerization triggered by ATP binding, not hydrolysis, leads to its association with XpsL | Shiue S.-J.; Kao K.-M.; Leu W.-M.; Chen L.-Y.; NEI-LI CHAN ; Hu N.-T. | EMBO Journal | 44 | 44 | |
2006 | 原核生物IIA型DNA拓撲異構酶辨認受質幾何構形機制之探討 | NEI-LI CHAN ; Tung-Ju Hsieh; Lynn Farh | 化學 | 0 | 0 | |
2004 | 蛋白質結構及其生技應用 | NEI-LI CHAN | 生物科技產學論壇 | 0 | 0 | |
2006 | 高效能大分子結晶學相位解析技術之發展現況 | NEI-LI CHAN ; Chia-Wang Chiang; Yi-Ching Li; Li-Ying Lin; Tung-Ju Hsieh | 科儀新知 | 0 | 0 | |