公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
---|---|---|---|---|---|---|
2002 | Characterization of some novel α1-adrenoceptor antagonists in human hyperplastic prostate | SHIH-CHIEH CHUEH ; Chern J.-W.; Choong C.-M.; JIH-HWA GUH ; Teng C.-M. | European Journal of Pharmacology | 6 | 6 | |
2001 | Conjugated polyhydroxybenzene derivatives block tumor necrosis factor-α-mediated nuclear factor-κB activation and cyclooxygenase-2 gene transcription by targeting IκB kinase activity | CHING-CHOW CHEN ; Chiu K.-T.; Chan S.-T.; Chern J.-W. | Molecular Pharmacology | 10 | 8 | |
2010 | Cytotoxicity and reversal of multidrug resistance by tryptanthrin-derived indoloquinazolines | Yu S.-T.; Chern J.-W.; Chen T.-M.; Chiu Y.-F.; Chen H.-T.; YEN-HUI CHEN | Acta Pharmacologica Sinica | 38 | 30 | |
2002 | Design, synthesis and biological evaluation of heterocycle-conjugated styrene derivatives as protein tyrosine kinase inhibitors and free radical scavengers | Chen C.-S.; Lai S.-Y.; Hsu P.-S.; Tsai C.-Y.; Fang C.-W.; MING-JAI SU ; Cheng F.-C.; Kao C.-L.; Chern J.-W. | Chinese Pharmaceutical Journal | 16 | ||
2009 | Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification | You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI ; Chern J.-W. | Journal of Medicinal Chemistry | 91 | 71 | |
2012 | Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide Derivatives as HCV NS5B Polymerase Inhibitors | Deore R.R.; Chen G.S.; Chang P.-T.; Chern T.-R.; Lai S.-Y.; Chuang M.-H.; Lin J.-H.; FAN-LU KUNG ; Chen C.-S.; Chiou C.-T.; Chern J.-W. | ChemMedChem | 11 | 12 | |
2012 | Efficient microwave-assisted Pd-catalyzed hydroxylation of aryl chlorides in the presence of carbonate | CHAO-WU YU ; Chen G.S.; Huang C.-W.; Chern J.-W. | Organic Letters | 65 | 59 | |
2003 | Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells | Pan S.-L.; JIH-HWA GUH ; Huang Y.-W.; Chern J.-W.; Chou J.-Y.; Teng C.-M. | Journal of Urology | 27 | 25 | |
2009 | An improved screening model to identify inhibitors targeting zinc-enhanced amyloid aggregation | Chang P.-T.; FAN-LU KUNG ; Talekar R.S.; Chen C.-S.; Lai S.-Y.; Lee H.-Y.; Chern J.-W. | Analytical Chemistry | 8 | 7 | |
2003 | Investigation of anticancer mechanism of thiadiazole-based compound in human non-small cell lung cancer A549 cells | Chou J.-Y.; Lai S.-Y.; Pan S.-L.; Jow G.-M.; Chern J.-W.; JIH-HWA GUH | Biochemical Pharmacology | 147 | 123 | |
2015 | A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth | Chang P.-T.; Talekar R.S.; FAN-LU KUNG ; Chern T.-R.; Huang C.-W.; Ye Q.-Q.; Yang M.-Y.; CHAO-WU YU ; Lai S.-Y.; Deore R.R.; Lin J.-H.; Chen C.-S.; Chen G.S.; Chern J.-W. | Neuropharmacology | 9 | 9 | |
2018 | Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs | Siriboon C.; Li T.-S.; CHAO-WU YU ; Chern J.-W.; Ju J.-C. | PLoS ONE | 3 | 2 | |
2019 | Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase-6 Inhibitors for Treatment of Non-Small Cell Lung Cancer | CHAO-WU YU ; Hung P.-Y.; Yang H.-T.; Ho Y.-H.; Lai H.-Y.; Cheng Y.-S. ; Chern J.-W. | Journal of Medicinal Chemistry | 38 | 36 | |
2013 | Quinazolin-4-one derivatives as selective histone deacetylase-6 inhibitors for the treatment of Alzheimer's disease | CHAO-WU YU ; Chang P.-T.; LING-WEI HSIN ; Chern J.-W. | Journal of Medicinal Chemistry | 90 | 82 | |
2009 | Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virus helicase | Chen C.-S.; Chiou C.-T.; Chen G.S.; Chen S.-C.; Hu C.-Y.; Chi W.-K.; Chu Y.-D.; Hwang L.-H.; PEI-JER CHEN ; Chen D.-S.; Liaw S.-H.; Chern J.-W. | Journal of Medicinal Chemistry | 53 | 50 |