公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
---|---|---|---|---|---|---|
2000 | The camptothecins: Unfolding their anticancer potential: Introduction | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Yong M.A.O.; Sun M.E.I.; Sai-Peng S.I.M. | Annals of the New York Academy of Sciences | 1 | ||
1996 | Cellular resistance to topoisomerase poisons. | Rubin E.H.; TSAI-KUN LI ; Duann P.; Liu L.F. | Cancer treatment and research | 37 | 0 | |
2003 | Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer Drug | TSAI-KUN LI ; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F. | Cancer Research | 101 | 97 | |
2002 | Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435 | Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry Letters | 56 | 56 | |
1997 | Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar | Sim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI ; Pilch D.S.; LaVoie E.J.; Liu L.F. | Biochemistry | 39 | 36 | |
2003 | DNA damage-mediated apoptosis induced by selenium compounds | Zhou N.; Xiao H.; TSAI-KUN LI ; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 135 | 128 | |
1998 | DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles | Xu Z.; TSAI-KUN LI ; Kim J.S.; LaVoie E.J.; Breslauer K.J.; Liu L.F.; Pilch D.S. | Biochemistry | 39 | 39 | |
2000 | Human topoisomerase I poisoning by protoberberines: Potential roles for both drug-DNA and drug-enzyme interactions | TSAI-KUN LI ; Bathory E.; LaVoie E.J.; Srinivasan A.R.; Olson W.K.; Sauers R.R.; Liu L.F.; Pilch D.S. | Biochemistry | 97 | 84 | |
2004 | Hydrogen Peroxide Induces Topoisomerase I-mediated DNA Damage and Cell Death | Daroui P.; Desai S.D.; TSAI-KUN LI ; Liu A.A.; Liu L.F. | Journal of Biological Chemistry | 118 | 112 | |
2003 | Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast | Qi H.; TSAI-KUN LI ; Kuo D.; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 56 | 55 | |
1997 | Incompatibility of Escherichia coli rho mutants with plasmids is mediated by plasmid-specific transcription | TSAI-KUN LI ; Panchenko Y.A.; Drolet M.; Liu L.F. | Journal of Bacteriology | 4 | 4 | |
2000 | Mechanism of action of camptothecin | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Mao Y.; Sun M.; Sim S.-P. | Annals of the New York Academy of Sciences | 449 | 390 | |
1998 | Modulation of gyrase-mediated DNA cleavage and cell killing by ATP | TSAI-KUN LI ; Liu L.F. | Antimicrobial Agents and Chemotherapy | 18 | 18 | |
2003 | Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)2,3-methylenedioxy-5H-dibenzo[c,h][1,6] naphthyridin-6-ones: Effect on topoisomerase-I targeting activity and cytotoxicity | Singh S.K.; Ruchelman A.L.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Journal of Medicinal Chemistry | 51 | 47 | |
2004 | Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N, N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Influence on topoisomerase I-targeting activity and cytotoxicity | Ruchelman A.L.; Kerrigan J.E.; TSAI-KUN LI ; Zhou N.; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 31 | 31 | |
1998 | Selective cytotoxicity of topoisomerase-directed protoberberines against glioblastoma cells | Sanders M.M.; Liu A.A.; TSAI-KUN LI ; Wu H.-Y.; Desai S.D.; Mao Y.; Rubin E.H.; LaVoie E.J.; Makhey D.; Liu L.F. | Biochemical Pharmacology | 55 | 52 | |
2003 | Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals | Nur-E-Kamal A.; TSAI-KUN LI ; Zhang A.; Qi H.; Hars E.S.; Liu L.F. | Journal of Biological Chemistry | 47 | 43 | |
2003 | Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents | Makhey D.; Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 45 | 45 | |
2003 | Substituted dibenzo[c,h]cinnolines: Topoisomerase I-targeting anticancer agents | Yu Y.; Singh S.K.; Liu A.; TSAI-KUN LI ; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 95 | 92 | |
2001 | Tumor cell death induced by topoisomerase-targeting drugs | TSAI-KUN LI ; Liu L.F. | Annual review of Pharmacology and Toxicology | 481 | 450 |