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Chern J.-W.
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顯示 1 到 17 筆資料,總共 17 筆
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scopus
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全文
2020
4-Substituted 2-amino-3,4-dihydroquinazolines with a 3-hairpin turn side chain as novel inhibitors of BACE-1
Jagtap A.D.; Kondekar N.B.; Hung P.-Y.; Hsieh C.-E.; CHIA-RON YANG
; Chen G.S.; Chern J.-W.
Bioorganic Chemistry
7
7
2010
Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: The roles of NF-κB and crosstalk between the extrinsic and intrinsic apoptotic pathways
Huang C.-H.; JIH-HWA GUH
; Chen G.S.; Lu P.-H.; Chern J.-W.
Naunyn-Schmiedeberg's Archives of Pharmacology
7
7
2002
Characterization of some novel α1-adrenoceptor antagonists in human hyperplastic prostate
SHIH-CHIEH CHUEH
; Chern J.-W.; Choong C.-M.; JIH-HWA GUH
; Teng C.-M.
European Journal of Pharmacology
6
6
2001
Conjugated polyhydroxybenzene derivatives block tumor necrosis factor-α-mediated nuclear factor-κB activation and cyclooxygenase-2 gene transcription by targeting IκB kinase activity
CHING-CHOW CHEN
; Chiu K.-T.; Chan S.-T.; Chern J.-W.
Molecular Pharmacology
10
8
2010
Cytotoxicity and reversal of multidrug resistance by tryptanthrin-derived indoloquinazolines
Yu S.-T.; Chern J.-W.; Chen T.-M.; Chiu Y.-F.; Chen H.-T.; YEN-HUI CHEN
Acta Pharmacologica Sinica
38
30
2002
Design, synthesis and biological evaluation of heterocycle-conjugated styrene derivatives as protein tyrosine kinase inhibitors and free radical scavengers
Chen C.-S.; Lai S.-Y.; Hsu P.-S.; Tsai C.-Y.; Fang C.-W.; MING-JAI SU
; Cheng F.-C.; Kao C.-L.; Chern J.-W.
Chinese Pharmaceutical Journal
16
2009
Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification
You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI
; Chern J.-W.
Journal of Medicinal Chemistry
91
71
2012
Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide Derivatives as HCV NS5B Polymerase Inhibitors
Deore R.R.; Chen G.S.; Chang P.-T.; Chern T.-R.; Lai S.-Y.; Chuang M.-H.; Lin J.-H.; FAN-LU KUNG
; Chen C.-S.; Chiou C.-T.; Chern J.-W.
ChemMedChem
11
12
2012
Efficient microwave-assisted Pd-catalyzed hydroxylation of aryl chlorides in the presence of carbonate
CHAO-WU YU
; Chen G.S.; Huang C.-W.; Chern J.-W.
Organic Letters
65
59
2003
Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells
Pan S.-L.; JIH-HWA GUH
; Huang Y.-W.; Chern J.-W.; Chou J.-Y.; Teng C.-M.
Journal of Urology
27
25
2009
An improved screening model to identify inhibitors targeting zinc-enhanced amyloid aggregation
Chang P.-T.; FAN-LU KUNG
; Talekar R.S.; Chen C.-S.; Lai S.-Y.; Lee H.-Y.; Chern J.-W.
Analytical Chemistry
8
7
2003
Investigation of anticancer mechanism of thiadiazole-based compound in human non-small cell lung cancer A549 cells
Chou J.-Y.; Lai S.-Y.; Pan S.-L.; Jow G.-M.; Chern J.-W.; JIH-HWA GUH
Biochemical Pharmacology
147
123
2015
A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth
Chang P.-T.; Talekar R.S.; FAN-LU KUNG
; Chern T.-R.; Huang C.-W.; Ye Q.-Q.; Yang M.-Y.; CHAO-WU YU
; Lai S.-Y.; Deore R.R.; Lin J.-H.; Chen C.-S.; Chen G.S.; Chern J.-W.
Neuropharmacology
9
9
2018
Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs
Siriboon C.; Li T.-S.; CHAO-WU YU
; Chern J.-W.; Ju J.-C.
PLoS ONE
3
2
2019
Quinazolin-2,4-dione-Based Hydroxamic Acids as Selective Histone Deacetylase-6 Inhibitors for Treatment of Non-Small Cell Lung Cancer
CHAO-WU YU
; Hung P.-Y.; Yang H.-T.; Ho Y.-H.; Lai H.-Y.; Cheng Y.-S.
; Chern J.-W.
Journal of Medicinal Chemistry
38
36
2013
Quinazolin-4-one derivatives as selective histone deacetylase-6 inhibitors for the treatment of Alzheimer's disease
CHAO-WU YU
; Chang P.-T.; LING-WEI HSIN
; Chern J.-W.
Journal of Medicinal Chemistry
90
82
2009
Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virus helicase
Chen C.-S.; Chiou C.-T.; Chen G.S.; Chen S.-C.; Hu C.-Y.; Chi W.-K.; Chu Y.-D.; Hwang L.-H.; PEI-JER CHEN
; Chen D.-S.; Liaw S.-H.; Chern J.-W.
Journal of Medicinal Chemistry
53
50