Issue Date | Title | Author(s) | Source | scopus | WOS | Fulltext/Archive link |
2013 | 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors | Lee H.-Y.; CHIA-RON YANG ; Lai M.-J.; Huang H.-L.; Hsieh Y.-L.; Liu Y.-M.; Yeh T.-K.; Li Y.-H.; Mehndiratta S.; Teng C.-M.; Liou J.-P. | ChemBioChem | 16 | 18 | |
2016 | 2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase | Lee H.-Y.; Chang C.-Y.; Su C.-J.; Huang H.-L.; Mehndiratta S.; Chao Y.-H.; Hsu C.-M.; Kumar S.; Sung T.-Y.; Huang Y.-Z.; Li Y.-H.; CHIA-RON YANG ; Liou J.-P. | European Journal of Medicinal Chemistry | 23 | 22 | |
2017 | 3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity | Lee H.-Y.; Lee J.-F.; Kumar S.; Wu Y.-W.; HuangFu W.-C.; Lai M.-J.; Li Y.-H.; Huang H.-L.; Kuo F.-C.; Hsiao C.-J.; Cheng C.-C.; CHIA-RON YANG ; Liou J.-P. | European Journal of Medicinal Chemistry | 35 | 33 | |
2018 | 5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes | Lee H.-Y.; Fan S.-J.; Huang F.-I.; Chao H.-Y.; Hsu K.-C.; Lin T.E.; Yeh T.-K.; Lai M.-J.; Li Y.-H.; Huang H.-L.; CHIA-RON YANG ; Liou J.-P. | Journal of Medicinal Chemistry | 46 | 43 | |
2012 | Anti-Arthritic effects of magnolol in human interleukin 1β-Stimulated Fibroblast-Like synoviocytes and in a rat arthritis model | JYH-HORNG WANG ; Shih K.-S.; Liou J.-P.; Wu Y.-W.; Chang A.S.-Y.; Wang K.-L.; Tsai C.-L.; CHIA-RON YANG | PLoS ONE | 26 | 17 | |
2017 | Anti-leukemia effects of the novel synthetic 1-benzylindole derivative 21-900 in vitro and in vivo | Huangfu W.-C.; Chao M.-W.; Cheng C.-C.; Wei Y.-C.; Wu Y.-W.; Liou J.-P.; Hsiao G.; Lee Y.-C.; CHIA-RON YANG | Scientific Reports | 3 | 4 | |
2019 | Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo | Hsieh Y.-L.; Tu H.-J.; Pan S.-L.; Liou J.-P.; CHIA-RON YANG | Biochimica et Biophysica Acta - Molecular Cell Research | 29 | 29 | |
2015 | Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis | Huang Y.-C.; Huang F.-I.; Mehndiratta S.; Lai S.-C.; Liou J.-P.; CHIA-RON YANG | Oncotarget | 19 | 20 | |
2018 | The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells | Tu H.-J.; Lin Y.-J.; Chao M.-W.; Sung T.-Y.; Wu Y.-W.; Chen Y.-Y.; Lin M.-H.; Liou J.-P.; Pan S.-L.; CHIA-RON YANG | Clinical Epigenetics | 19 | 20 | |
2014 | Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes | CHIA-RON YANG ; Shih K.-S.; Liou J.-P.; Wu Y.-W.; Hsieh I.-N.; Lee H.-Y.; Lin T.-C.; JYH-HORNG WANG | Journal of Molecular Medicine | 31 | 22 | |
2020 | HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen-glucose deprivation injuries via H3K14 and H4K5 acetylation-mediated BDNF expression | Fang Y.-C.; Chan L.; Liou J.-P.; YONG-KWANG TU ; Lai M.-J.; Chen C.-I.; Vidyanti A.N.; Lee H.-Y.; Hu C.-J. | Journal of Cellular and Molecular Medicine | 5 | 5 | |
2014 | Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity | Mehndiratta S.; Hsieh Y.-L.; Liu Y.-M.; Wang A.W.; Lee H.-Y.; Liang L.-Y.; Kumar S.; Teng C.-M.; CHIA-RON YANG ; Liou J.-P. | European Journal of Medicinal Chemistry | 39 | 38 | |
2013 | Inside Cover: 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors (ChemBioChem 10/2013) | Lee H.-Y.; CHIA-RON YANG ; Lai M.-J.; Huang H.-L.; Hsieh Y.-L.; Liu Y.-M.; Yeh T.-K.; Li Y.-H.; Mehndiratta S.; Teng C.-M.; Liou J.-P. | ChemBioChem | 0 | 0 | |
2014 | Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2 | Hou P.; CHING-YING KUO ; Cheng C.-T.; Liou J.-P.; Ann D.K.; Chen Q. | PLoS ONE | 22 | 22 | |
2019 | MPT0G413, A novel HDAC6-selective inhibitor, and bortezomib synergistically exert anti-tumor activity in multiple myeloma cells | Huang F.-I.; Wu Y.-W.; Sung T.-Y.; Liou J.-P.; Lin M.-H.; Pan S.-L.; CHIA-RON YANG | Frontiers in Oncology | 17 | 17 | |
2018 | (N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo | Lee H.-Y.; Nepali K.; Huang F.-I.; Chang C.-Y.; Lai M.-J.; Li Y.-H.; Huang H.-L.; CHIA-RON YANG ; Liou J.-P. | Journal of Medicinal Chemistry | 55 | 52 | |
2021 | A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo | Wu Y.-W.; Chao M.-W.; Tu H.-J.; Chen L.-C.; Hsu K.-C.; Liou J.-P.; CHIA-RON YANG ; Yen S.-C.; HuangFu W.-C.; Pan S.-L. | Oncogenesis | 11 | 8 | |
2018 | The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model article | Fan S.-J.; Huang F.-I.; Liou J.-P.; CHIA-RON YANG | Cell Death and Disease | 56 | 58 | |
2016 | Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma | Chen M.-C.; Huang H.-H.; Lai C.-Y.; Lin Y.-J.; Liou J.-P.; Lai M.-J.; Li Y.-H.; Teng C.-M.; CHIA-RON YANG | Oncotarget | 19 | 19 | |
1996 | Novel radical synthesis of morphine fragments spiro[benzofuran-3(2H),4'-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline | Cheng C.-Y.; LING-WEI HSIN ; Liou J.-P. | Tetrahedron | 24 | 21 | |