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  1. NTU Scholars

利用孔雀魚檢測環境雄性激素

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Project title/計畫英文名
利用孔雀魚檢測環境雄性激素
 
Project Number/計畫編號
94-2313-B-002-094-
 
Translated Name/計畫中文名
利用孔雀魚檢測環境雄性激素
 
Project Principal Investigator/計畫主持人
MEI - HUI LI
 
Funding Organization
National Science and Technology Council
 
Start date/計畫起
01-08-2005
Expected Completion/計畫迄
31-07-2006
 

Description

Abstract
摘要:目前已有證據顯示環境中同時有雄性激素干擾物質及雌性激素干擾物質存在,但是我們對於環境雄性激素干擾物質的現狀或對野生動物的影響尚不清楚,本計畫目的是發展一整合型魚類生物指標之生物測試方法來檢測環境中的雄性及雌性激素干擾物質。將選擇以測量雄性孔雀魚體表的橘色點大小,做為暴露到環境雄性激素的指標,再配合本研究室過去兩年已發展的測量孔雀魚體內卵黃前質(vitellogenin)含量做為暴露到環境雌性激素的指標。並將進一步探討在孔雀魚暴露到雄性激素或環境雄性激素,體內蝶酸(pteridine)合成的作用是否是一可能形成體表的橘色點增加的機制。
Abstract: There is increasing evidence showing that both environmental androgens and environmental estrogens presented in our surroundings. But little is known about the status of environmental androgens in our living environment and the effects of environmental androgens in wildlife. The objective of this study is to evaluate the usefulness of guppies as an integrated bioassay which can be used to detect both environmental androgens and environmental estrogens at the same time. The size of orange spots in male guppy is proposed to be used as an endpoint to detect environmental androgens and the induction of vitellogenin is used as an endpoint to detect environmental estrogens. In addition, the potential mechanism of increase orange pigments induced by testosterone and/or environmental androgens will be examined by pteridine biosynthesis pathway.

 
Keyword(s)
孔雀魚
環境雄性激素
環境雌性激素
卵黃前質
蝶酸
guppy
environmental androgens
environmental estrogens
vitellogenin
pteridine
 

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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