第 1 到 76 筆結果,共 76 筆。
公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 | |
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1 | 2022 | Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells | Costanzo, Federico; Martínez Diez, Marta; Santamaría Nuñez, Gema; Díaz-Hernandéz, Juan Ignacio; Genes Robles, Carlos Mario; Díez Pérez, Javier; Compe, Emmanuel; Ricci, Romeo; TSAI-KUN LI ; Coin, Frédéric; Martínez Leal, Juan Fernando; Garrido-Martin, Eva Maria; Egly, Jean Marc | EMBO molecular medicine | 13 | ||
2 | 2022 | Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicity | Yeh Y.-H.; Tsai C.-C.; Chen T.-W.; Lee C.-H.; Chang W.-J.; Hsieh M.-Y.; TSAI-KUN LI | Molecular and Cellular Biochemistry | 3 | 3 | |
3 | 2020 | Retraction notice to "Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases" [Eur. J. Med. Chem. 190 (2020) 112074] | Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; TSAI-KUN LI ; Lee, Sung-Bau; Lin, Mei-Hsiang | European journal of medicinal chemistry | 0 | 0 | |
4 | 2020 | The role of extracellular vesicles in prostate cancer with clinical applications | Tai, Y.-L.; Lin, C.-J.; TSAI-KUN LI ; Shen, T.-L.; Hsieh, J.-T.; TANG-LONG SHEN | Endocrine-Related Cancer | 12 | 11 | |
5 | 2020 | Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase–negative cells | Zencir S.; Hsieh M.-H.; Hsu J.-S.; Ergun Y.; Chou G.-L.; TSAI-KUN LI ; Teng S.-C.; Topcu Z. | Journal of Cancer Research and Clinical Oncology | 3 | 3 | |
6 | 2020 | Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases | Lee, Jiann-Fong; Chang, Ting-Yu; Liu, Zheng-Fang; Lee, Nian-Zhe; Yeh, Yen-Hsiu; Chen, Yi-Song; Chen, Tsung-Chih; Chou, Hao-Syun; TSAI-KUN LI ; Lee, Sung-Bau; Lin, Mei-Hsiang | European Journal of Medicinal Chemistry | 10 | 9 | |
7 | 2019 | The paracrine induction of prostate cancer progression by caveolin-1 | Lin, C.-J.; Yun, E.-J.; Lo, U.-G.; Tai, Y.-L.; Deng, S.; Hernandez, E.; Dang, A.; Chen, Y.-A.; Saha, D.; Mu, P.; Lin, H.; TSAI-KUN LI ; Shen, T.-L.; Lai, C.-H.; TANG-LONG SHEN | Cell Death and Disease | 39 | 37 | |
8 | 2018 | Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway | Yeh Y.-H.; Hsiao H.-F.; Yeh Y.-C.; Chen T.-W.; TSAI-KUN LI | Journal of Experimental and Clinical Cancer Research | 53 | 50 | |
9 | 2018 | Regioselective synthesis and biological evaluation of: N -substituted 2-aminoquinazolin-4-ones | Liao Z.-Y.; Yeh W.-H.; Liao P.-Y.; Liu Y.-T.; Chen Y.-C.; Chen Y.-H.; Hsieh T.-H.; Lin C.-C.; Lu M.-H.; Chen Y.-S.; Hsu M.-C.; TSAI-KUN LI ; Chien T.-C. | Organic and Biomolecular Chemistry | 13 | 13 | |
10 | 2017 | MicroRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1 | Lin H.-C.; Liu S.-Y.; Yen E.-Y.; TSAI-KUN LI ; I-RUE LAI | Antioxidants and Redox Signaling | 11 | 10 | |
11 | 2017 | Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts | Chien, M.-H.; Lee T.-H.; Lee W.-J.; Yeh Y.-H.; TSAI-KUN LI ; Wang P.-C.; Chen J.-J.; Chow J.-M.; Lin Y.-W.; Hsiao M.; Wang S.-W.; TZONG-HUEI LEE et al. | Cancer Letters | 14 | 12 | |
12 | 2017 | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry | Wang Y.-R.; Chen S.-F.; Wu C.-C.; Liao Y.-W.; Lin T.-S.; Liu K.-T.; Chen Y.-S.; TSAI-KUN LI ; Chien T.-C.; NEI-LI CHAN | Nucleic Acids Research | 60 | 60 | |
13 | 2016 | Rhapontigenin inhibits TGF-β-mediated epithelial-mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation | Yeh Y.-H.; Wang S.-W.; Yeh Y.-C.; Hsiao H.-F.; TSAI-KUN LI | Oncology Reports | 18 | 20 | |
14 | 2015 | Involvement of p38 MAPK in the anticancer activity of cultivated cordyceps militaris | Chou S.-M.; Lai W.-J.; Hong T.; Tsai S.-H.; Chen Y.-H.; Kao C.-H.; Chu R.; Shen T.-L.; TSAI-KUN LI | American Journal of Chinese Medicine | 8 | 6 | |
15 | 2015 | Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers | Hsieh M.-H.; Tsai C.-H.; Hung J.-J.; TSAI-KUN LI ; SHU-CHUN TENG ; Chang L.-T.; LING-WEI HSIN ; Teng S.-C. | Cellular and Molecular Life Sciences | 8 | 9 | |
16 | 2015 | Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential | Wang Y.-W.; Hong T.-W.; Tai Y.-L.; Wang Y.-J.; Tsai S.-H.; Lien P.T.K.; Chou T.-H.; Lai J.-Y.; Chu R.; Ding S.-T.; Irie K.; TSAI-KUN LI ; Tzean S.-S.; Shen T.-L. | Evidence-based Complementary and Alternative Medicine | 11 | 6 | |
17 | 2014 | Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells | Chou S.-M.; Lai W.-J.; Hong T.-W.; Lai J.-Y.; Tsai S.-H.; Chen Y.-H.; Yu S.-H.; Kao C.-H.; Chu R.; Ding S.-T.; TSAI-KUN LI ; Shen T.-L. | Phytomedicine | 36 | 27 | |
18 | 2014 | DNA topoisomerase III alpha regulates P53-mediated tumor suppression | Hsieh, Mei-Yi; Fan, Jia-Rong; Chang, Han-Wen; Chen, Hsiang-Chin; TANG-LONG SHEN ; SHU-CHUN TENG ; Yeh, Yen-Hsiu; TSAI-KUN LI | Clinical Cancer Research | 10 | 8 | |
19 | 2014 | A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i | Yu C.-C.; Pan S.-L.; Chao S.-W.; SHIH-PING LIU ; Hsu J.-L.; Yang Y.-C.; TSAI-KUN LI ; Huang W.-J.; JIH-HWA GUH | Biochemical Pharmacology | 29 | 28 | |
20 | 2013 | A negative feedback of the HIF-1α pathway via interferon-stimulated gene 15 and ISGylation | Yeh Y.-H.; Yang Y.-C.; Hsieh M.-Y.; Yeh Y.-C.; TSAI-KUN LI | Clinical Cancer Research | 30 | 25 | |
21 | 2013 | Topoisomerase II-mediated DNA cleavage and mutagenesis activated by nitric oxide underlie the inflammation-associated tumorigenesis | Yang Y.-C.; HAN-YI E. CHOU ; Shen T.-L.; Chang W.-J.; Tai P.-H.; TSAI-KUN LI | Antioxidants and Redox Signaling | 19 | 18 | |
22 | 2013 | DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia | Lin B.-C.; Su L.-H.; Weng S.-C.; Pan Y.-J.; NEI-LI CHAN ; TSAI-KUN LI ; Wang H.-C.; CHIN-HUNG SUN | PLoS Neglected Tropical Diseases | 11 | 9 | |
23 | 2013 | On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs | Wu C.-C.; Li Y.-C.; Wang Y.-R.; TSAI-KUN LI ; NEI-LI CHAN | Nucleic Acids Research | 137 | 134 | |
24 | 2012 | QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells | Chen M.-C.; Pan S.-L.; Shi Q.; Xiao Z.; Lee K.-H.; TSAI-KUN LI ; Teng C.-M. | Cancer Science | 15 | 13 | |
25 | 2012 | Cell type-specific effects of Adenosine 5′-triphosphate and pyrophosphate on the antitumor activity of doxorubicin | Wang J.-S.; Chang Y.-L.; Yu Y.-H.; Chen C.-Y.; Kao M.-C.; TSAI-KUN LI ; WAN-WAN LIN | Cancer Science | 5 | 5 | |
26 | 2012 | Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles | Lee C.-H.; Hsieh M.-Y.; LING-WEI HSIN ; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; NEI-LI CHAN ; TSAI-KUN LI | Biochemical Pharmacology | 12 | 12 | |
27 | 2012 | Docosahexaenoic acid suppresses the expression of FoxO and its target genes | Chen Y.-J.; Chen C.-C.; TSAI-KUN LI ; Wang P.-H.; Liu L.-R.; Chang F.-Y.; Wang Y.-C.; Yu Y.-H.; Lin S.-P.; Mersmann H.J.; PEI-HWA WANG | Journal of Nutritional Biochemistry | 41 | 39 | |
28 | 2012 | Multiple domains of the Tobacco mosaic virus p126 protein can independently suppress local and systemic RNA silencing | Wang L.-Y.; Lin S.-S.; Hung T.-H.; TSAI-KUN LI ; Lin N.-C.; NAI-CHUN LIN ; SHIH-SHUN LIN | Molecular Plant-Microbe Interactions | 48 | 45 | |
29 | 2012 | Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway | Hsu J.-L.; Ho Y.-F.; TSAI-KUN LI ; Chen C.-S.; LIH-CHING HSU ; JIH-HWA GUH | Biochemical Pharmacology | 18 | 16 | |
30 | 2011 | Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway | Toh Y.-M.; TSAI-KUN LI | Clinical Cancer Research | 27 | 27 | |
31 | 2011 | Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide | Wu C.-C.; TSAI-KUN LI ; Farh L.; Lin L.-Y.; Lin T.-S.; Yu Y.-J.; Yen T.-J.; Chiang C.-W.; NEI-LI CHAN | Science | 388 | 380 | |
32 | 2011 | Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2 | Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI | Cellular and Molecular Life Sciences | 9 | 8 | |
33 | 2010 | EGF-induced Grb7 recruits and promotes ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells | Chu P.-Y.; TSAI-KUN LI ; Ding S.-T.; I-RUE LAI ; Shen T.-L. | Journal of Biological Chemistry | 39 | 38 | |
34 | 2010 | Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses | Fan J.-R.; Huang T.-H.; Wen C.-Y.; Shen T.-L.; TSAI-KUN LI | European Journal of Pharmacology | 4 | 4 | |
35 | 2010 | Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage | Huang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI | Cell Research | 13 | 12 | |
36 | 2009 | Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism | Tai C.C.; Chen C.Y.; Lee, Hsuan-Shu ; Wang Y.C.; TSAI-KUN LI ; Mersamm H.J.; Ding S.T.; PEI-HWA WANG | Journal of Biological Chemistry | 22 | 22 | |
37 | 2009 | Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification | You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI ; Chern J.-W. | Journal of Medicinal Chemistry | 91 | 71 | |
38 | 2008 | Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates | LING-WEI HSIN ; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; JIH-HWA GUH ; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI ; Lee C.-H. | Bioorganic and Medicinal Chemistry | 45 | 41 | |
39 | 2008 | WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers | Hsiao C.-J.; TSAI-KUN LI ; Chan Y.-L.; LING-WEI HSIN ; Liao C.-H.; Lee C.-H.; Lyu P.-C.; JIH-HWA GUH | Biochemical Pharmacology | 35 | 32 | |
40 | 2008 | Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses | Fan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI | DNA Repair | 47 | 43 | |
41 | 2007 | Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult | Yeh T.-C.; Chiang P.-C.; TSAI-KUN LI ; Hsu J.-L.; CHUN-JUNG LIN ; Wang S.-W.; Peng C.-Y.; JIH-HWA GUH | Biochemical Pharmacology | 123 | 110 | |
42 | 2007 | Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication | Lu C.-C.; Huang H.-T.; Wang J.-T.; Slupphaug G.; TSAI-KUN LI ; Wu M.-C.; Chen Y.-C.; Lee C.-P.; MEI-RU CHEN | Journal of Virology | 30 | 29 | |
43 | 2007 | Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycle | Lin S.-C.; SHIH-CHIEH CHUEH ; Hsiao C.-J.; TSAI-KUN LI ; Chen T.-H.; Liao C.-H.; Lyu P.-C.; JIH-HWA GUH | Neoplasia | 61 | 58 | |
44 | 2006 | Involvement of topoisomerase III in telomere-telomere recombination | SHU-CHUN TENG ; Huang W.-H.; TSAI-KUN LI ; Tsai Y.-L.; Wu K.-J.; Tseng S.-F.; Teng S.-C. | Journal of Biological Chemistry | 43 | 41 | |
45 | 2006 | Distribution of gyrase and topoisomerase IV on bacterial nucleoid: Implications for nucleoid organization | Hsu Y.-H.; Chung M.-W.; TSAI-KUN LI | Nucleic Acids Research | 30 | 28 | |
46 | 2006 | Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells | Chiang P.-C.; FAN-LU KUNG ; Huang D.-M.; TSAI-KUN LI ; Fan J.-R.; Pan S.-L.; Shen Y.-C.; JIH-HWA GUH | European Journal of Pharmacology | 23 | 24 | |
47 | 2004 | Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N, N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Influence on topoisomerase I-targeting activity and cytotoxicity | Ruchelman A.L.; Kerrigan J.E.; TSAI-KUN LI ; Zhou N.; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 31 | 31 | |
48 | 2004 | Drug targeting of HIV-1 RNA·DNA hybrid structures: Thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication | TSAI-KUN LI ; Barbieri C.M.; Lin H.-C.; Rabson A.B.; Yang G.; Fan Y.; Gaffney B.L.; Jones R.A.; Pilch D.S. | Biochemistry | 19 | 18 | |
49 | 2004 | Hydrogen Peroxide Induces Topoisomerase I-mediated DNA Damage and Cell Death | Daroui P.; Desai S.D.; TSAI-KUN LI ; Liu A.A.; Liu L.F. | Journal of Biological Chemistry | 118 | 112 | |
50 | 2003 | Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents | Makhey D.; Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 45 | 45 | |
51 | 2003 | 8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity | Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 40 | 41 | |
52 | 2003 | Aza-analogs of dibenzo[c,h]cinnoline: Triazachrysenes as potent topoisomerase I-targeting anticancer agents | Singh S.K.; Ruchelman A.L.; Zhou N.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Medicinal Chemistry Research | 8 | ||
53 | 2003 | 5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity | Ruchelman A.L.; Singh S.K.; Ray A.; Wu X.H.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 111 | 109 | |
54 | 2003 | Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast | Qi H.; TSAI-KUN LI ; Kuo D.; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 56 | 55 | |
55 | 2003 | Aminoglycoside complexation with a DNA·RNA hybrid duplex: The thermodynamics of recognition and inhibition of RNA processing enzymes | Barbieri C.M.; TSAI-KUN LI ; Guo S.; Wang G.; Shallop A.J.; Pan W.; Yang G.; Gaffney B.L.; Jones R.A.; Pilch D.S. | Journal of the American Chemical Society | 31 | 28 | |
56 | 2003 | Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer Drug | TSAI-KUN LI ; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F. | Cancer Research | 101 | 97 | |
57 | 2003 | Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)2,3-methylenedioxy-5H-dibenzo[c,h][1,6] naphthyridin-6-ones: Effect on topoisomerase-I targeting activity and cytotoxicity | Singh S.K.; Ruchelman A.L.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Journal of Medicinal Chemistry | 51 | 47 | |
58 | 2003 | Acidic pH induces topoisomerase II-mediated DNA damage | Xiao H.; TSAI-KUN LI ; Yang J.-M.; Liu L.F. | Proceedings of the National Academy of Sciences of the United States of America | 68 | 54 | |
59 | 2003 | Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals | Nur-E-Kamal A.; TSAI-KUN LI ; Zhang A.; Qi H.; Hars E.S.; Liu L.F. | Journal of Biological Chemistry | 47 | 43 | |
60 | 2003 | Substituted dibenzo[c,h]cinnolines: Topoisomerase I-targeting anticancer agents | Yu Y.; Singh S.K.; Liu A.; TSAI-KUN LI ; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 95 | 92 | |
61 | 2003 | DNA damage-mediated apoptosis induced by selenium compounds | Zhou N.; Xiao H.; TSAI-KUN LI ; Nur-E-Kamal A.; Liu L.F. | Journal of Biological Chemistry | 135 | 128 | |
62 | 2002 | 2,3-Dimethoxybenzo[i]phenanthridines: Topoisomerase I-targeting anticancer agents | Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry | 50 | 51 | |
63 | 2002 | Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435 | Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI ; Liu A.; Liu L.F.; LaVoie E.J. | Bioorganic and Medicinal Chemistry Letters | 56 | 56 | |
64 | 2001 | Ubiquitin/26s proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells | Desai S.D.; TSAI-KUN LI ; Rodriguez-Bauman A.; Liu L.F.; Rubin E.H. | Cancer Research | 196 | 191 | |
65 | 2001 | Tumor cell death induced by topoisomerase-targeting drugs | TSAI-KUN LI ; Liu L.F. | Annual review of Pharmacology and Toxicology | 481 | 450 | |
66 | 2000 | The camptothecins: Unfolding their anticancer potential: Introduction | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Yong M.A.O.; Sun M.E.I.; Sai-Peng S.I.M. | Annals of the New York Academy of Sciences | 1 | ||
67 | 2000 | Mechanism of action of camptothecin | Liu L.F.; Desai S.D.; TSAI-KUN LI ; Mao Y.; Sun M.; Sim S.-P. | Annals of the New York Academy of Sciences | 449 | 390 | |
68 | 2000 | Human topoisomerase I poisoning by protoberberines: Potential roles for both drug-DNA and drug-enzyme interactions | TSAI-KUN LI ; Bathory E.; LaVoie E.J.; Srinivasan A.R.; Olson W.K.; Sauers R.R.; Liu L.F.; Pilch D.S. | Biochemistry | 97 | 84 | |
69 | 2000 | Ubiquitin, SUMO-1, and UCRP in camptothesin sensitivity and resistance | Desai S.D.; Yong M.A.O.; Sun M.E.I.; TSAI-KUN LI ; Jiaxi W.U.; Liu L.F.; New Jersey | Annals of the New York Academy of Sciences | 24 | 21 | |
70 | 1999 | Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress | TSAI-KUN LI ; Chen A.Y.; Yu C.; Mao Y.; Wang H.; Liu L.F. | Genes and Development | 150 | 139 | |
71 | 1998 | Selective cytotoxicity of topoisomerase-directed protoberberines against glioblastoma cells | Sanders M.M.; Liu A.A.; TSAI-KUN LI ; Wu H.-Y.; Desai S.D.; Mao Y.; Rubin E.H.; LaVoie E.J.; Makhey D.; Liu L.F. | Biochemical Pharmacology | 55 | 52 | |
72 | 1998 | DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles | Xu Z.; TSAI-KUN LI ; Kim J.S.; LaVoie E.J.; Breslauer K.J.; Liu L.F.; Pilch D.S. | Biochemistry | 39 | 39 | |
73 | 1998 | Modulation of gyrase-mediated DNA cleavage and cell killing by ATP | TSAI-KUN LI ; Liu L.F. | Antimicrobial Agents and Chemotherapy | 18 | 18 | |
74 | 1997 | Incompatibility of Escherichia coli rho mutants with plasmids is mediated by plasmid-specific transcription | TSAI-KUN LI ; Panchenko Y.A.; Drolet M.; Liu L.F. | Journal of Bacteriology | 4 | 4 | |
75 | 1997 | Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar | Sim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI ; Pilch D.S.; LaVoie E.J.; Liu L.F. | Biochemistry | 39 | 36 | |
76 | 1996 | Cellular resistance to topoisomerase poisons. | Rubin E.H.; TSAI-KUN LI ; Duann P.; Liu L.F. | Cancer treatment and research | 37 | 0 |