Publications



Results 1-100 of 100 (Search time: 0.038 seconds).

Issue DateTitleAuthor(s)SourcescopusWOSFulltext/Archive link
12021Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemiaChang, Ya-Hsuan; Yu, Chih-Hsiang; Jou, Shiann-Tarng; Lin, Chien-Yu; Lin, Kai-Hsin; Lu, Meng-Yao; Wu, Kang-Hsi; Chang, Hsiu-Hao; Lin, Dong-Tsamn; SHU-WHA LIN ; Chen, Hsuan-Yu; Yang, Yung-LiScientific reports76
22020Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasisAdair B.D.; Alonso J.L.; van Agthoven J.; Hayes V.; Ahn H.S.; Yu I.-S.; SHU-WHA LIN ; Xiong J.-P.; Poncz M.; Arnaout M.A.Nature Communications1615
32020Childhood acute lymphoblastic leukemia mercaptopurine intolerance is associated with NUDT15 variantsWang D.-S.; Yu C.-H.; Lin C.-Y.; Chang Y.-H.; Lin K.-H.; Lin D.-T.; Jou S.-T.; Lu M.-Y.; Chang H.-H.; SHU-WHA LIN ; Chen H.-Y.; Yang Y.-L.Pediatric Research56
42020Determination of NUDT15 variants by targeted sequencing can identify compound heterozygosity in pediatric acute lymphoblastic leukemia patientsYu, Chih-Hsiang; Chang, Ya-Hsuan; Wang, Der-Shiun; Jou, Shiann-Tarng; Lin, Chien-Yu; Lin, Kai-Hsin; Lu, Meng-Yao; Raghav, Lovely; Chang, Hsiu-Hao; Wu, Kang-Hsi; Chou, Shu-Wei; Ni, Yu-Ling; Lin, Dong-Tsamn; SHU-WHA LIN ; Chen, Hsuan-Yu; Yang, Yung-LiScientific reports66
52020Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosisPai, Chen-Hsueh; Lin, Shu-Rung; Liu, Chia-Hao; Pan, Szu-Yu; Hsu, Hao; Chen, Yi-Ting; Yen, Ching-Tzu; Yu, I-Shing; Wu, Hua-Lin; Lin, Shuei-Liong; SHU-WHA LIN Scientific reports44
62019P53 ICE CRIM mouse: A tool to generate mutant allelic series in somatic cells and germ lines for cancer studiesFan H.-H.; Shing Yu I.; Lin Y.-H.; Wang S.-Y.; Liaw Y.-H.; Chen P.-L.; Yang T.-L.; SHU-WHA LIN ; Chen Y.-T.FASEB Journal11
72019Tumor Endothelial Marker 1 (TEM1/Endosialin/CD248) Enhances Wound Healing by Interacting with Platelet-Derived Growth Factor ReceptorsHong Y.-K.; Lee Y.-C.; Cheng T.-L.; Lai C.-H.; Hsu C.-K.; Kuo C.-H.; Hsu Y.-Y.; Li J.-T.; Chang B.-I.; Ma C.-Y.; SHU-WHA LIN ; Wang K.-C.; Shi G.-Y.; Wu H.-L.Journal of Investigative Dermatology89
82019Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cellsChen C.-Y.; Yu I.-S.; Pai C.-H.; Lin C.-Y.; Lin S.-R.; Chen Y.-T.; SHU-WHA LIN PLoS ONE11
92019The combination of MK-2206 and WZB117 exerts a synergistic cytotoxic effect against breast cancer cellsLi Y.-L.; Weng H.-C.; Hsu J.-L.; SHU-WHA LIN ; Guh J.-H.; Hsu L.-C.Frontiers in Pharmacology1615
102018Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146bCho S.; Lee H.-M.; Yu I.-S.; Choi Y.S.; Huang H.-Y.; Hashemifar S.S.; Lin L.-L.; Chen M.-C.; Afanasiev N.D.; Khan A.A.; SHU-WHA LIN ; Rudensky A.Y.; Crotty S.; Lu L.-F.Nature Communications4142
112018The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathwaySung H.-C.; Liu C.-W.; Hsiao C.-Y.; Lin S.-R.; Yu I.-S.; SHU-WHA LIN ; Chiang M.-H.; Liang C.-J.; Pu C.-M.; Chen Y.-C.; Lin M.-S.; Chen Y.-L.Phytomedicine1313
122018Traversal of the Blood-Brain Barrier by Cleavable l -Lysine Conjugates of ApigeninWong T.-Y.; Tsai M.-S.; Hsu L.-C.; SHU-WHA LIN ; Liang P.-H.Journal of Agricultural and Food Chemistry22
132018Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in miceChang C.-K.; Lin X.-R.; Lin Y.-L.; Fang W.-H.; SHU-WHA LIN ; Chang S.-Y.; Kao J.-T.PLoS ONE87
142018Sensory nerve degeneration in a mouse model mimicking early manifestations of familial amyloid?polyneuropathy due to transthyretin Ala97SerKan H.-W.; Chiang H.; Lin W.-M.; Yu I.-S.; SHU-WHA LIN ; Hsieh S.-T.Neuropathology and Applied Neurobiology66
152017Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: Evidence for an anti-inflammatory cascade mediated by the MIR-221/222/AMPK/p38/NF-7kappa;B pathwayLiu C.-W.; Sung H.-C.; Lin S.-R.; Wu C.-W.; Lee C.-W.; Lee I.-T.; Yang Y.-F.; Yu I.-S.; SHU-WHA LIN ; Chiang M.-H.; Liang C.-J.; Chen Y.-L.Scientific Reports660
162017The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: Molecular mechanisms and implications for extracellular matrix turnoverWilkinson D.J.; Desilets A.; Lin H.; Charlton S.; Del Carmen Arques M.; Falconer A.; Bullock C.; Hsu Y.-C.; Birchall K.; Hawkins A.; Thompson P.; Ferrell W.R.; Lockhart J.; Plevin R.; Zhang Y.; Blain E.; SHU-WHA LIN ; Leduc R.; Milner J.M.; Rowan A.D.Scientific Reports1924
172016A novel thromboxane receptor antagonist, nstpbp5185, inhibits platelet aggregation and thrombus formation in animal modelsHuang S.-W.; Kuo H.-L.; Hsu M.-T.; Tseng Y.J.; SHU-WHA LIN ; Kuo S.-C.; Peng H.-C.; Lien J.-C.; Huang T.-F.Thrombosis and Haemostasis1110
182016Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4TZU-MING JAO ; Li Y.-L.; SHU-WHA LIN ; Tzeng S.-T.; Yu I.-S.; Yen S.-J.; MONG-HSUN TSAI ; YA-CHIEN YANG Oncotarget1110
192016Hepatocyte-like cells derived from mouse induced pluripotent stem cells produce functional coagulation factor IX in a hemophilia B mouse modelWu Y.-M.; Huang Y.-J.; Chen P.; Hsu Y.-C.; SHU-WHA LIN ; Lai H.-S.; Lee H.-S.Cell Transplantation54
202016Lack of thromboxane synthase prevents hypertension and fetal growth restriction after high salt treatment during pregnancyPai C.-H.; Yen C.-T.; Chen C.-P.; Yu I.-S.; SHU-WHA LIN ; Lin S.-R.PLoS ONE76
212016Human X-linked Intellectual Disability Factor CUL4B Is Required for Post-meiotic Sperm Development and Male FertilityLin C.-Y.; Chen C.-Y.; Yu C.-H.; Yu I.-S.; Lin S.-R.; Wu J.-T.; Lin Y.-H.; Kuo P.-L.; Wu J.-C.; SHU-WHA LIN Scientific Reports1713
222016Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet SyndromeHsiao J.; Yuan T.Y.; Tsai M.S.; Lu C.Y.; Lin Y.C.; Lee M.L.; SHU-WHA LIN ; Chang F.C.; Liu Pimentel H.; Olive C.; Coito C.; Shen G.; Young M.; Thorne T.; Lawrence M.; Magistri M.; Faghihi M.A.; Khorkova O.; Wahlestedt C.EBioMedicine8580
232016Current animal models of hemophilia: The state of the artYen C.-T.; Fan M.-N.; Yang Y.-L.; Chou S.-C.; Yu I.-S.; SHU-WHA LIN Thrombosis Journal220
242015Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant dravet syndrome model during developmentTsai M.-S.; Lee M.-L.; Chang C.-Y.; Fan H.-H.; Yu I.-S.; Chen Y.-T.; You J.-Y.; Chen C.-Y.; Chang F.-C.; Hsiao J.H.; Khorkova O.; Liou H.-H.; Yanagawa Y.; Lee L.-J.; SHU-WHA LIN Neurobiology of Disease3027
252015Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient miceLiao H.-J.; Chyuan I.-T.; Wu C.-S.; SHU-WHA LIN ; Chen K.-H.; Tsai H.-F.; Hsu P.-N.Rheumatology (United Kingdom)2117
262015Sun1 deficiency leads to cerebellar ataxia in miceWang J.-Y.; Yu I.-S.; Huang C.-C.; Chen C.-Y.; Wang W.-P.; SHU-WHA LIN ; Jeang K.-T.; Chi Y.-H.DMM Disease Models and Mechanisms2120
272015A double negative loop comprising ETV6/RUNX1 and MIR181A1 contributes to differentiation block in t(12;21)-positive acute lymphoblastic leukemiaYang Y.-L.; Yen C.-T.; Pai C.-H.; Chen H.-Y.; Yu S.-L.; Lin C.-Y.; Hu C.-Y.; Jou S.-T.; Lin D.-T.; Lin S.-R.; SHU-WHA LIN PLoS ONE119
282015A Single Mirna-Mrna Interaction Affects The Immune Response In A Context- And Cell-Type-Specific MannerLu L.-F.; Gasteiger G.; Yu I.-S.; Chaudhry A.; Hsin J.-P.; Lu Y.; Bos P.D.; Lin L.-L.; Zawislak C.L.; Cho S.; Sun J.C.; Leslie C.S.; SHU-WHA LIN ; Rudensky A.Y.Immunity129126
292014Enhanced LPS-induced peritonitis in mice deficiency of cullin 4B in macrophagesHung M.-H.; Jian Y.-R.; Tsao C.-C.; SHU-WHA LIN ; Chuang Y.-H.Genes and Immunity1414
302014Impaired thrombin generation in Reelin-deficient mice: A potential role of plasma Reelin in hemostasisTseng W.-L.; Chen T.-H.; Huang C.-C.; Huang Y.-H.; Yeh C.-F.; Tsai H.-J.; Lee H.-Y.; Kao C.-Y.; SHU-WHA LIN ; Liao H.-R.; Cheng J.-C.; Tseng C.-P.Journal of Thrombosis and Haemostasis1918
312014Monitoring liver function among patients who initiated antituberculosis drugs in Taiwan, 2000-2011Chou H-C.; SHU-WHA LIN ; Chen W-W.; Ke W-M.; Chao P-H.; Hsiao F-Y.International Journal of Tuberculosis and Lung Disease33
322014Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type i interferonHo B.-C.; Yu I.-S.; Lu L.-F.; Rudensky A.; Chen H.-Y.; Tsai C.-W.; Chang Y.-L.; Wu C.-T.; Chang L.-Y.; Shih S.-R.; SHU-WHA LIN ; Lee C.-N.; Yang P.-C.; Yu S.-L.Nature Communications104102
332014A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cellsJIN-BON HONG ; Chou F.-J.; Ku A.T.; Fan H.-H.; Lee T.-L.; Huang Y.-H.; TSUNG-LIN YANG ; Su I.-C.; Yu I.-S.; SHU-WHA LIN ; CHUNG-LIANG CHIEN ; HONG-NERNG HO ; YOU-TZUNG CHEN PLoS ONE44
342013SEPT12-Microtubule complexes are required for sperm head and tail formationKuo P.-L.; Chiang H.-S.; Wang Y.-Y.; Kuo Y.-C.; Chen M.-F.; Yu I.-S.; Teng Y.-N.; SHU-WHA LIN ; Lin Y.-H.International Journal of Molecular Sciences1820
352013Phosphorylation regulates NCC stability and transporter activity in vivoYang S.-S.; Fang Y.-W.; Tseng M.-H.; Chu P.-Y.; Yu I.-S.; Wu H.-C.; SHU-WHA LIN ; Chau T.; Uchida S.; Sasaki S.; Lin Y.-F.; Sytwu H.-K.; Lin S.-H.Journal of the American Society of Nephrology4141
362013Incorporation of the factor IX Padua mutation into FIX-Triple improves clotting activity in vitro and in vivoKao C.-Y.; Yang S.-J.; Tao M.-H.; Jeng Y.-M.; Yu I.-S.; SHU-WHA LIN Thrombosis and Haemostasis2826
372013Differences in the Pathogenicity of the p.H723R Mutation of the Common Deafness-Associated SLC26A4 Gene in Humans and MiceLu Y.-C.; Wu C.-C.; Yang T.-H.; Lin Y.-H.; Yu I.-S.; SHU-WHA LIN ; Chang Q.; Lin X.; Wong J.-M.; Hsu C.-J.PLoS ONE2015
382012Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemiaYUNG-LI YANG ; Hsiao C.-C.; Chen H.-Y.; Lin K.-H.; SHIANN-TANG JOU ; Chen J.-S.; Chang T.-K.; Sheen J.-M.; SUNG-LIANG YU ; MENG-YAO LU ; Cheng C.-N.; Wu K.-H.; Wang S.-C.; Wang J.-D.; HSIU-HAO CHANG ; Lin S.-R.; SHU-WHA LIN ; Lin D.-T.Pediatric Blood and Cancer1413
392012Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in miceHsu Y.-C.; Huang H.-P.; Yu I.-S.; Su K.-Y.; Lin S.-R.; Lin W.-C.; Wu H.-L.; Shi G.-Y.; Tao M.-H.; Kao C.-H.; Wu Y.-M.; Martin P.E.; Lin S.-Y.; Yang P.-C.; SHU-WHA LIN Hepatology2422
402012A Knock-In Npm1 Mutation in Mice Results in Myeloproliferation and Implies a Perturbation in Hematopoietic MicroenvironmentChou S.-H.; Ko B.-S.; Chiou J.-S.; Hsu Y.-C.; Tsai M.-H.; Chiu Y.-C.; Yu I.-S.; SHU-WHA LIN ; Hou H.-A.; Kuo Y.-Y.; Lin H.-M.; Wu M.-F.; Chou W.-C.; Tien H.-F.PLoS ONE1816
412012Monocytic thrombomodulin triggers LPS- and gram-negative bacteria-induced inflammatory responseMa C.-Y.; Shi G.-Y.; Shi C.-S.; Kao Y.-C.; SHU-WHA LIN ; Wu H.-L.Journal of Immunology2322
422012Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardationChen C.-Y.; Tsai M.-S.; Lin C.-Y.; Yu I.-S.; Chen Y.-T.; Lin S.-R.; Juan L.-W.; Chen Y.-T.; Hsu H.-M.; Lee L.-J.; SHU-WHA LIN Human Molecular Genetics3839
432012R26R-GR: A Cre-Activable Dual Fluorescent Protein Reporter MouseChen Y.-T.; Tsai M.-S.; Yang T.-L.; Ku A.T.; Huang K.-H.; Huang C.-Y.; Chou F.-J.; Fan H.-H.; Hong J.-B.; Yen S.-T.; Wang W.-L.; Lin C.-C.; Hsu Y.-C.; Su K.-Y.; Su I.-C.; Jang C.-W.; Behringer R.R.; Favaro R.; Nicolis S.K.; Chien C.-L.; SHU-WHA LIN ; Yu I.-S.PLoS ONE1210
442012Functional importance of apolipoprotein A5 185G in the activation of lipoprotein lipaseHuang Y.-J.; Lin Y.-L.; Chiang C.-I.; Yen C.-T.; SHU-WHA LIN ; Kao J.-T.Clinica Chimica Acta1716
452011Severe metabolic acidosis causes early lethality in NBC1 W516X knock-in mice as a model of human isolated proximal renal tubular acidosisLo Y.-F.; Yang S.-S.; Seki G.; Yamada H.; Horita S.; Yamazaki O.; Fujita T.; Usui T.; Tsai J.-D.; Yu I.-S.; SHU-WHA LIN ; Lin S.-H.Kidney International4743
462011SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryosLin Y.-H.; Chou C.-K.; Hung Y.-C.; Yu I.-S.; Pan H.-A.; SHU-WHA LIN ; Kuo P.-L.Fertility and Sterility2729
472011Impaired phosphorylation of Na +-K +-2Cl - cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndromeLin S.-H.; Yu I.-S.; Jiang S.-T.; SHU-WHA LIN ; Chu P.; Chen A.; Sytwu H.-K.; Sohara E.; Uchida S.; Sasaki S.; Yang S.-S.Proceedings of the National Academy of Sciences of the United States of America101100
482011Establishment of a knock-in mouse model with the SLC26A4 c.919-2a>G mutation and characterization of its pathologyLu Y.-C.; Wu C.-C.; Shen W.-S.; Yang T.-H.; Yeh T.-H.; Chen P.-J.; Yu I.-S.; SHU-WHA LIN ; Wong J.-M.; Chang Q.; Lin X.; Hsu C.-J.PLoS ONE4037
492011Gene targeting and expression analysis of mouse Tem1/endosialin using a lacZ reporterHuang H.-P.; Hong C.-L.; Kao C.-Y.; SHU-WHA LIN ; Lin S.-R.; Wu H.-L.; Shi G.-Y.; You L.-R.; Wu C.-L.; Yu I.-S.Gene Expression Patterns1815
502010SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstrictionYang S.-S.; Lo Y.-F.; Wu C.-C.; SHU-WHA LIN ; Yeh C.-J.; Chu P.; Sytwu H.-K.; Uchida S.; Sasaki S.; Lin S.-H.Journal of the American Society of Nephrology225217
512010Pharmacogenomic variations in treatment protocols for childhood acute lymphoblastic leukemiaYang Y.-L.; Lin D.-T.; Chang S.-K.; Lin S.-R.; SHU-WHA LIN ; Chiou R.-J.; Yen C.-T.; Lin K.-H.; Jou S.-T.; Lu M.-Y.; Chang H.-H.; Chang W.-H.; Lin K.-S.; Hu C.-Y.Pediatric Blood and Cancer1714
522010Expression and prognostic significance of the apoptotic genes BCL2L13, Livin, and CASP8AP2 in childhood acute lymphoblastic leukemiaYang Y.-L.; Lin S.-R.; Chen J.-S.; SHU-WHA LIN ; Yu S.-L.; Chen H.-Y.; Yen C.-T.; Lin C.-Y.; Lin J.-F.; Lin K.-H.; Jou S.-T.; Hu C.-Y.; Chang S.-K.; Lu M.-Y.; Chang H.-H.; Chang W.-H.; Lin K.-S.; Lin D.-T.Leukemia Research3129
532010Genetic modification of donor hepatocytes improves therapeutic efficacy for hemophilia B in miceWu Y.-M.; Kao C.-Y.; Huang Y.-J.; Yu I.-S.; Lee H.-S.; Lai H.-S.; Lee P.-H.; Lin C.-N.; SHU-WHA LIN Cell Transplantation99
542010Multiplex reverse transcription-polymerase chain reaction as diagnostic molecular screening of 4 common fusion chimeric genes in Taiwanese children with acute lymphoblastic leukemiaYang Y.-L.; Lin S.-R.; Chen J.-S.; Hsiao C.-C.; Lin K.-H.; Sheen J.-M.; Cheng C.-N.; Wu K.-H.; SHU-WHA LIN ; Yu S.-L.; Chen H.-Y.; Lu M.-Y.; Chang H.-H.; Yen C.-T.; Lin J.-F.; Su Y.-H.; Li Y.-P.; Lin C.-Y.; Jou S.-T.; Lin D.-T.Journal of Pediatric Hematology/Oncology117
552010Generation of a novel factor IX with augmented clotting activities in vitro and in vivoLin C.N.; Kao C.Y.; Miao C.H.; Hamaguchi N.; Wu H.L.; Shi G.Y.; Liu Y.L.; High K.A.; SHU-WHA LIN Journal of Thrombosis and Haemostasis1918
562010Generation and analysis of the thiazide-sensitive Na+-Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndromeYang S.; Lo Y.; Yu I.; SHU-WHA LIN ; Chang T.; Hsu Y.; Chao T.; Sytwu H.; Uchida S.; Sasaki S.; Lin S.Human Mutation5145
572009Mitochondrial genomic instability in colorectal cancer: No correlation to nuclear microsatellite instability and allelic deletion of hMSH2, hMLH1, and p53 Genes, but prediction of better survival for dukes' stage C diseaseTsai M.-H.; Fang W.-H.; SHU-WHA LIN ; Yen S.-J.; Chou S.-J.; Yang Y.-C.Annals of Surgical Oncology1312
582009The expression level of septin12 is critical for spermiogenesisLin Y.-H.; Lin Y.-M.; Wang Y.-Y.; Yu I.-S.; Lin Y.-W.; Wang Y.-H.; Wu C.-M.; Pan H.-A.; Chao S.-C.; Yen P.H.; SHU-WHA LIN ; Kuo P.-L.American Journal of Pathology7067
592009Common sequence variant in lipoprotein lipase gene conferring triglyceride response to fibrate treatmentKUO-LIONG CHIEN ; Lin Y.-L.; Wen H.-C.; Lin H.-P.; Yen C.-T.; SHU-WHA LIN ; JAU-TSUEN KAO Pharmacogenomics65
602007Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memorySu K.-Y.; Chien W.-L.; Fu W.-M.; Yu I.-S.; Huang H.-P.; Huang P.-H.; Lin S.-R.; Shih J.-Y.; Lin Y.-L.; Hsueh Y.-P.; Yang P.-C.; SHU-WHA LIN Journal of Neuroscience7070
612007L2dtl is essential for cell survival and nuclear division in early mouse embryonic developmentLiu C.-L.; Yu I.-S.; Pan H.-W.; SHU-WHA LIN ; Hsu H.-C.Journal of Biological Chemistry2121
622006Decreased expressions of hepsin in human hepatocellular carcinomasChen C.-H.; Su K.-Y.; Tao M.-H.; SHU-WHA LIN ; Su Y.-H.; Tsai Y.-C.; Cheng K.-C.; Jeng Y.-M.; Sheu J.-C.Liver International1618
632004Identification of residues Asn89, Ile90, and Val 107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated plateletsYang X.; Chang Y.-J.; SHU-WHA LIN ; Walsh P.N.Journal of Biological Chemistry129
642004TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced deathYu I.-S.; Lin S.-R.; Huang C.-C.; Tseng H.-Y.; Huang P.-H.; Shi G.-Y.; Wu H.-L.; Tang C.-L.; Chu P.-H.; Wang L.-H.; Wu K.K.; SHU-WHA LIN Blood4337
652004A novel mutation with Ins C (882-883) of the factor X gene in a Taiwanese Chinese factor X-deficient familyShen M.-C.; Lin J.-S.; Lin D.S.-Y.; SHU-WHA LIN ; Lin B.Thrombosis and Haemostasis22
662003SOCSI methylation in patients with newly diagnosed acute myeloid leukemiaChen C.-Y.; Tsay W.; Tang J.-L.; Shen H.-L.; SHU-WHA LIN ; Huang S.-Y.; Yao M.; Chen Y.-C.; Shen M.-C.; Wang C.-H.; Tien H.-F.Genes Chromosomes and Cancer10384
672003A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemiaKao J.-T.; Wen H.-C.; Chien K.-L.; Hsu H.-C.; SHU-WHA LIN Human Molecular Genetics155147
682003Discontinuous residues of factor IX constitute a surface for binding the anti-factor IX monoclonal antibody A-5Chang Y.-J.; Wu H.-L.; Hsu Y.-C.; Hamaguchi N.; Shi G.-Y.; Shen M.-C.; SHU-WHA LIN Thrombosis Research77
692002Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis: Residues Asn89-Gly93 are critical for binding factor VIIIaChang Y.-J.; Wu H.-L.; Hamaguchi N.; Hsu Y.-C.; SHU-WHA LIN Journal of Biological Chemistry3232
702001The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitorsHsu Y.-C.; Hamaguchi N.; Chang Y.-J.; SHU-WHA LIN Biochemistry109
712001Domain specific monoclonal anti-factor VIII antibodies generated by inclusion body-renatured factor VIII peptidesHuang C.-C.; Li L.-T.; Shen M.-C.; Chen J.-Y.; SHU-WHA LIN Thrombosis Research12
722001Epitope mapping of factor VIII inhibitor antibodies of Chinese originHuang C.-C.; Shen M.-C.; Chen J.-Y.; Hung M.-H.; Hsu T.-C.; SHU-WHA LIN British Journal of Haematology99
732001Novel mutations in the factor VII gene of Taiwanese factor VII-deficient patientsShen M.-C.; Lin J.-S.; SHU-WHA LIN ; Yang W.-S.; Lin B.British Journal of Haematology1010
742000Chimaeric mice with disruption of the gene coding for phosphatidylinositol glycan class A (Pig-a) were defective in embryogenesis and spermatogenesisLin S.-R.; Yu I.-S.; Huang P.-H.; Tsai C.-W.; SHU-WHA LIN British Journal of Haematology67
752000Hemophilia B with mutations at Glycine-48 of factor IX exhibited delayed activation by the factor VIIa-tissue factor complexWu P.-C.; Hamaguchi N.; Yu Y.-S.; Shen M.-C.; SHU-WHA LIN Thrombosis and Haemostasis1413
762000Mice deficient in hepsin, a serine protease, exhibit normal embryogenesis and unchanged hepatocyte regeneration abilityYu I.-S.; Chen H.-J.; Lee Y.-S.E.; Huang P.-H.; Lin S.-R.; Tsai T.-W.; SHU-WHA LIN Thrombosis and Haemostasis3839
772000Intracellular localization of factor VIII in normal liver tissues and in cirrhosis by immunoelectron microscopyLi L.T.; Liu Y.L.; Huang C.C.; SHU-WHA LIN ; Shen Mc.Fibrinolysis and Proteolysis0
782000Identification of a new CA-dinucleotide repeat marker for diagnosis of hemophilia aLin S.R.; Hsu Y.-C.; Shen M.C.; SHU-WHA LIN Fibrinolysis and Proteolysis0
792000Identification of functionally important residues in the epidermal growth factor-like domain of factor IX by alanine scanning mutagenesisSHU-WHA LIN Fibrinolysis and Proteolysis0
802000Identification of a new CA dinucleotide repeat in the human factor VIII geneLin S.-R.; SHU-WHA LIN ; Hsu Y.-C.; Shen M.-C.British Journal of Haematology97
811999Engineered recombinant factor VII Q217 variants with altered inhibitor specificitiesChang Y.-J.; Hamaguchi N.; Chang S.-C.; Ruf W.; Shen M.-C.; SHU-WHA LIN Biochemistry1515
821998Tissue factor activity of SW-480 human colon adenocarcinoma cells is modulated by thrombin and protein kinase C activationChiang H.-S.; Yang R.-S.; SHU-WHA LIN ; Huang T.-F.British Journal of Cancer108
831997Antigenicity of a synthetic peptide from glucosyltransferases of Streptococcus mutans in humansChia J.-S.; SHU-WHA LIN ; Yang C.-S.; Chen J.-Y.Infection and Immunity1917
841995Genetic diagnosis of haemophilia A of Chinese originLin S.?R.; Chang S.?C.; Lee C.?C.; Shen M.?C.; SHU-WHA LIN British Journal of Haematology1111
851994Genetic alterations at the splice junction of p53 gene in human hepatocellular carcinomaHsu H.?C.; Huang A.?M.; Lai P.?L.; Chien W.?M.; Peng S.?Y.; SHU-WHA LIN Hepatology2929
861994Characterization of a factor IX variant with a glycine207 to glutamic acid mutationSHU-WHA LIN ; Lin C.-N.; Hamaguchi N.; Smith K.J.; Shen M.-C.Blood66
871994Functional analysis of the amino terminus of Epstein-Barr virus deoxyribonucleaseLin S.-F.; SHU-WHA LIN ; Hsu T.-Y.; Liu M.-Y.; Chen J.-Y.; Yang C.-S.Virology1111
881993Inhibition of glucosyltransferase activities of Streptococcus mutans by a monoclonal antibody to a subsequence peptideChia J.-S.; Lin R.-H.; SHU-WHA LIN ; Chen J.-Y.; Yang C.-S.Infection and Immunity3941
891993Characterization of genetic defects of hemophilia A in patients of chinese originSHU-WHA LIN ; Lin S.-R.; Shen M.-C.Genomics3640
901993Genetic basis and carrier detection of hemophilia B of Chinese originSHU-WHA LIN ; Shen M.-C.Thrombosis and Haemostasis1517
911993Analysis of a DNA polymorphic region in the gtfB and gtfC genes of Streptococcus mutansChia J.-S.; SHU-WHA LIN ; Hsu T.-Y.; Chen J.-Y.; Kwan H.-W.; Yang C.-S.Infection and Immunity1518
921991Cloning and characterization of cDNA clones corresponding to transcripts from the BamHI G region of the Epstein-Barr virus genome and expression of BGLF2Chen M.-R.; Hsu T.-Y.; SHU-WHA LIN ; Chen J.-Y.; Yang C.-S.Journal of General Virology1113
931991The role of the epidermal growth factor-1 and hydrophobic stack domains of human factor IX in binding to endothelial cellsCheung W.-F.; Straight D.L.; Smith K.J.; SHU-WHA LIN ; Roberts H.R.; Stafford D.W.Journal of Biological Chemistry2630
941991Characterization of genetic defects of hemophilia B of Chinese originSHU-WHA LIN ; Shen M.-C.Thrombosis and Haemostasis1013
951990Expression and characterization of human factor IX and factor IX-factor X chimeras in mouse C127 cellsSHU-WHA LIN ; Smith K.J.; Welsch D.; Stafford D.W.Journal of Biological Chemistry5580
961990Factor IX New London: Substitution of proline for glutamine at position 50 causes severe hemophilia BLozier J.N.; Monroe D.M.; Stanfield-Oakley S.; SHU-WHA LIN ; Smith K.J.; Roberts H.R.; High K.A.Blood3041
971989Mapping of monoclonal antibodies to human factor IXFrazier D.; Smith K.J.; Cheung W.-F.; Ware J.; SHU-WHA LIN ; Thompson A.R.; Reisner H.; Bejaj S.P.; Stafford D.W.Blood3244
981987Expression of Human Factor IX and Its Subfragments in Escherichia coli and Generation of Antibodies to the SubfragmentstSHU-WHA LIN ; Stafford D.W.; Dunn J.J.; Studier F.W.Biochemistry1220
991987Vectors for selective expression of cloned DNAs by T7 RNA polymeraseRosenberg A.H.; Lade B.N.; Dao-shan C.; SHU-WHA LIN ; Dunn J.J.; Studier F.W.Gene10401385
1001987Carrier testing in hemophilia B with an immunoassay that distinguishes a prevalent factor IX dimorphismSmith K.J.; Thompson A.R.; McMullen B.A.; Frazier D.; SHU-WHA LIN ; Stafford D.; Kisiel W.; Thibodeau S.N.; Chen S.-H.; Smith L.F.Blood925