第 1 到 35 筆結果,共 35 筆。
公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 | |
---|---|---|---|---|---|---|---|
1 | 2020 | Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis | Adair B.D.; Alonso J.L.; van Agthoven J.; Hayes V.; Ahn H.S.; Yu I.-S.; SHU-WHA LIN ; Xiong J.-P.; Poncz M.; Arnaout M.A. | Nature Communications | 27 | 22 | |
2 | 2018 | Sensory nerve degeneration in a mouse model mimicking early manifestations of familial amyloid polyneuropathy due to transthyretin Ala97Ser | Kan H.-W.; Chiang H.; Lin W.-M.; Yu I.-S.; SHU-WHA LIN ; SUNG-TSANG HSIEH | Neuropathology and Applied Neurobiology | 9 | 9 | |
3 | 2018 | The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway | Sung H.-C.; Liu C.-W.; Hsiao C.-Y.; Lin S.-R.; Yu I.-S.; SHU-WHA LIN ; Chiang M.-H.; Liang C.-J.; Pu C.-M.; Chen Y.-C.; Lin M.-S.; YUH-LIEN CHEN | Phytomedicine | 19 | 14 | |
4 | 2018 | Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b | Cho S.; Lee H.-M.; Yu I.-S.; Choi Y.S.; Huang H.-Y.; Hashemifar S.S.; Lin L.-L.; Chen M.-C.; Afanasiev N.D.; Khan A.A.; SHU-WHA LIN ; Rudensky A.Y.; Crotty S.; Lu L.-F. | Nature Communications | 51 | 48 | |
5 | 2017 | Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: Evidence for an anti-inflammatory cascade mediated by the MIR-221/222/AMPK/p38/NF-7kappa;B pathway | Liu C.-W.; Sung H.-C.; Lin S.-R.; Wu C.-W.; Lee C.-W.; Lee I.-T.; Yang Y.-F.; Yu I.-S.; SHU-WHA LIN ; Chiang M.-H.; Liang C.-J.; YUH-LIEN CHEN | Scientific Reports | 72 | 75 | |
6 | 2016 | Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4 | TZU-MING JAO ; Li Y.-L.; SHU-WHA LIN ; Tzeng S.-T.; Yu I.-S.; Yen S.-J.; MONG-HSUN TSAI ; YA-CHIEN YANG | Oncotarget | 14 | 15 | |
7 | 2016 | Human X-linked Intellectual Disability Factor CUL4B Is Required for Post-meiotic Sperm Development and Male Fertility | Lin C.-Y.; Chen C.-Y.; Yu C.-H.; Yu I.-S.; Lin S.-R.; Wu J.-T.; Lin Y.-H.; Kuo P.-L.; JUI-CHING WU ; SHU-WHA LIN | Scientific Reports | 18 | 14 | |
8 | 2016 | Current animal models of hemophilia: The state of the art | Yen C.-T.; Fan M.-N.; YUNG-LI YANG ; SHENG-CHIEH CHOU ; Yu I.-S.; SHU-WHA LIN | Thrombosis Journal | 24 | 0 | |
9 | 2016 | Lack of thromboxane synthase prevents hypertension and fetal growth restriction after high salt treatment during pregnancy | Pai C.-H.; Yen C.-T.; Chen C.-P.; Yu I.-S.; SHU-WHA LIN ; Lin S.-R. | PLoS ONE | 8 | 6 | |
10 | 2015 | A Single Mirna-Mrna Interaction Affects The Immune Response In A Context- And Cell-Type-Specific Manner | Lu L.-F.; Gasteiger G.; Yu I.-S.; Chaudhry A.; Hsin J.-P.; Lu Y.; Bos P.D.; Lin L.-L.; Zawislak C.L.; Cho S.; Sun J.C.; Leslie C.S.; SHU-WHA LIN ; Rudensky A.Y. | Immunity | 141 | 136 | |
11 | 2015 | Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant dravet syndrome model during development | Tsai M.-S.; Lee M.-L.; Chang C.-Y.; Fan H.-H.; Yu I.-S.; YOU-TZUNG CHEN ; You J.-Y.; Chen C.-Y.; Chang F.-C.; Hsiao J.H.; Khorkova O.; HORNG-HUEI LIOU ; Yanagawa Y.; LI-JEN LEE ; SHU-WHA LIN | Neurobiology of Disease | 39 | 34 | |
12 | 2015 | Sun1 deficiency leads to cerebellar ataxia in mice | Wang J.-Y.; Yu I.-S.; Huang C.-C.; Chen C.-Y.; Wang W.-P.; SHU-WHA LIN ; Jeang K.-T.; Chi Y.-H. | DMM Disease Models and Mechanisms | 25 | 24 | |
13 | 2014 | Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type i interferon | Ho B.-C.; Yu I.-S.; Lu L.-F.; Rudensky A.; Chen H.-Y.; Tsai C.-W.; YIH-LEONG CHANG ; CHEN-TU WU ; LUAN-YIN CHANG ; Shih S.-R.; SHU-WHA LIN ; Lee C.-N.; PAN-CHYR YANG ; SUNG-LIANG YU | Nature Communications | 114 | 110 | |
14 | 2014 | A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells | JIN-BON HONG ; Chou F.-J.; Ku A.T.; Fan H.-H.; Lee T.-L.; Huang Y.-H.; TSUNG-LIN YANG ; Su I.-C.; Yu I.-S.; SHU-WHA LIN ; CHUNG-LIANG CHIEN ; HONG-NERNG HO ; YOU-TZUNG CHEN | PLoS ONE | 4 | 4 | |
15 | 2013 | Incorporation of the factor IX Padua mutation into FIX-Triple improves clotting activity in vitro and in vivo | Kao C.-Y.; Yang S.-J.; Tao M.-H.; YUNG-MING JENG ; Yu I.-S.; SHU-WHA LIN | Thrombosis and Haemostasis | 34 | 30 | |
16 | 2013 | Phosphorylation regulates NCC stability and transporter activity in vivo | Yang S.-S.; Fang Y.-W.; Tseng M.-H.; Chu P.-Y.; Yu I.-S.; Wu H.-C.; SHU-WHA LIN ; Chau T.; Uchida S.; Sasaki S.; Lin Y.-F.; Sytwu H.-K.; Lin S.-H. | Journal of the American Society of Nephrology | 45 | 43 | |
17 | 2013 | SEPT12-Microtubule complexes are required for sperm head and tail formation | Kuo P.-L.; Chiang H.-S.; Wang Y.-Y.; Kuo Y.-C.; Chen M.-F.; Yu I.-S.; Teng Y.-N.; SHU-WHA LIN ; Lin Y.-H. | International Journal of Molecular Sciences | 21 | 22 | |
18 | 2013 | Differences in the Pathogenicity of the p.H723R Mutation of the Common Deafness-Associated SLC26A4 Gene in Humans and Mice | Lu Y.-C.; Chen-Chi Wu ; TING-HUA YANG ; Lin Y.-H.; Yu I.-S.; SHU-WHA LIN ; Chang Q.; Lin X.; Wong J.-M.; Hsu C.-J. | PLoS ONE | 23 | 17 | |
19 | 2012 | Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardation | Chen C.-Y.; Tsai M.-S.; Lin C.-Y.; Yu I.-S.; YOU-TZUNG CHEN ; Lin S.-R.; Juan L.-W.; Hsu H.-M.; LI-JEN LEE ; SHU-WHA LIN | Human Molecular Genetics | 44 | 43 | |
20 | 2012 | A Knock-In Npm1 Mutation in Mice Results in Myeloproliferation and Implies a Perturbation in Hematopoietic Microenvironment | Chou S.-H.; BOR-SHENG KO ; Chiou J.-S.; Hsu Y.-C.; MONG-HSUN TSAI ; Chiu Y.-C.; Yu I.-S.; SHU-WHA LIN ; HSIN-AN HOU ; Kuo Y.-Y.; Lin H.-M.; Wu M.-F.; WEN-CHIEN CHOU ; HWEI-FANG TIEN | PLoS ONE | 20 | 17 | |
21 | 2012 | Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice | Hsu Y.-C.; HSIANG-PO HUANG ; Yu I.-S.; KANG-YI SU ; Lin S.-R.; WEI-CHOU LIN ; Wu H.-L.; Shi G.-Y.; Tao M.-H.; Kao C.-H.; YAO-MING WU ; Martin P.E.; Lin S.-Y.; PAN-CHYR YANG ; SHU-WHA LIN | Hepatology | 27 | 24 | |
22 | 2012 | R26R-GR: A Cre-Activable Dual Fluorescent Protein Reporter Mouse | YOU-TZUNG CHEN ; Tsai M.-S.; TSUNG-LIN YANG ; Ku A.T.; Huang K.-H.; Huang C.-Y.; Chou F.-J.; Fan H.-H.; JIN-BON HONG ; Yen S.-T.; Wang W.-L.; Lin C.-C.; Hsu Y.-C.; KANG-YI SU ; Su I.-C.; Jang C.-W.; Behringer R.R.; Favaro R.; Nicolis S.K.; CHUNG-LIANG CHIEN ; SHU-WHA LIN ; Yu I.-S. | PLoS ONE | 13 | 10 | |
23 | 2011 | Establishment of a knock-in mouse model with the SLC26A4 c.919-2a>G mutation and characterization of its pathology | Lu Y.-C.; Chen-Chi Wu ; Shen W.-S.; TING-HUA YANG ; TE-HUEI YEH ; PEI-JER CHEN ; Yu I.-S.; SHU-WHA LIN ; Wong J.-M.; Chang Q.; Lin X.; Hsu C.-J. | PLoS ONE | 42 | 39 | |
24 | 2011 | Impaired phosphorylation of Na +-K +-2Cl - cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome | Lin S.-H.; Yu I.-S.; Jiang S.-T.; SHU-WHA LIN ; Chu P.; Chen A.; Sytwu H.-K.; Sohara E.; Uchida S.; Sasaki S.; Yang S.-S. | Proceedings of the National Academy of Sciences of the United States of America | 108 | 106 | |
25 | 2011 | Severe metabolic acidosis causes early lethality in NBC1 W516X knock-in mice as a model of human isolated proximal renal tubular acidosis | Lo Y.-F.; Yang S.-S.; Seki G.; Yamada H.; Horita S.; Yamazaki O.; Fujita T.; Usui T.; Tsai J.-D.; Yu I.-S.; SHU-WHA LIN ; Lin S.-H. | Kidney International | 47 | 43 | |
26 | 2011 | Gene targeting and expression analysis of mouse Tem1/endosialin using a lacZ reporter | HSIANG-PO HUANG ; Hong C.-L.; Kao C.-Y.; SHU-WHA LIN ; Lin S.-R.; Wu H.-L.; Shi G.-Y.; You L.-R.; Wu C.-L.; Yu I.-S. | Gene Expression Patterns | 25 | 19 | |
27 | 2011 | SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryos | Lin Y.-H.; Chou C.-K.; Hung Y.-C.; Yu I.-S.; Pan H.-A.; SHU-WHA LIN ; Kuo P.-L. | Fertility and Sterility | 29 | 29 | |
28 | 2010 | Genetic modification of donor hepatocytes improves therapeutic efficacy for hemophilia B in mice | YAO-MING WU ; Kao C.-Y.; Huang Y.-J.; Yu I.-S.; Lee, Hsuan-Shu ; HONG-SHIEE LAI ; PO-HUANG LEE ; Lin C.-N.; SHU-WHA LIN | Cell Transplantation | 9 | 9 | |
29 | 2010 | FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis | Kao C.-Y.; Lin C.-N.; Yu I.-S.; Tao M.-H.; Wu H.-L.; Shi G.-Y.; YUNG-LI YANG ; JAU-TSUEN KAO ; SHU-WHA LIN | Thrombosis and Haemostasis | 12 | 10 | |
30 | 2009 | The expression level of septin12 is critical for spermiogenesis | Lin Y.-H.; Lin Y.-M.; Wang Y.-Y.; Yu I.-S.; Lin Y.-W.; Wang Y.-H.; Wu C.-M.; Pan H.-A.; Chao S.-C.; Yen P.H.; SHU-WHA LIN ; Kuo P.-L. | American Journal of Pathology | 75 | 72 | |
31 | 2007 | Mice deficient in collapsin response mediator protein-1 exhibit impaired long-term potentiation and impaired spatial learning and memory | KANG-YI SU ; Chien W.-L.; WEN-MEI FU ; Yu I.-S.; HSIANG-PO HUANG ; PEI-HSIN HUANG ; Lin S.-R.; JIN-YUAN SHIH ; Lin Y.-L.; Hsueh Y.-P.; PAN-CHYR YANG ; SHU-WHA LIN | Journal of Neuroscience | 76 | 74 | |
32 | 2007 | L2dtl is essential for cell survival and nuclear division in early mouse embryonic development | Liu C.-L.; Yu I.-S.; Pan H.-W.; SHU-WHA LIN ; Hsu H.-C. | Journal of Biological Chemistry | 21 | 21 | |
33 | 2004 | TXAS-deleted mice exhibit normal thrombopoiesis, defective hemostasis, and resistance to arachidonate-induced death | Yu I.-S.; Lin S.-R.; Huang C.-C.; Tseng H.-Y.; PEI-HSIN HUANG ; Shi G.-Y.; Wu H.-L.; Tang C.-L.; Chu P.-H.; Wang L.-H.; Wu K.K.; SHU-WHA LIN | Blood | 45 | 39 | |
34 | 2000 | Mice deficient in hepsin, a serine protease, exhibit normal embryogenesis and unchanged hepatocyte regeneration ability | Yu I.-S.; Chen H.-J.; Lee Y.-S.E.; PEI-HSIN HUANG ; Lin S.-R.; Tsai T.-W.; SHU-WHA LIN | Thrombosis and Haemostasis | 38 | 40 | |
35 | 2000 | Chimaeric mice with disruption of the gene coding for phosphatidylinositol glycan class A (Pig-a) were defective in embryogenesis and spermatogenesis | Lin S.-R.; Yu I.-S.; PEI-HSIN HUANG ; Tsai C.-W.; SHU-WHA LIN | British Journal of Haematology | 6 | 7 |