研究成果


第 1 到 48 筆結果，共 48 筆。

公開日期標題作者來源出版物scopusWOS全文
120235,6-Dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) induces apoptosis in breast cancer cells through inhibiting of Mcl-1 expressionKuo, Yi-Hsuan; Lai, Tsai-Chun; Chang, Chia-Hsin; Hsieh, Han-Ching; Yang, Feng-Ming; MENG-CHUN HU Scientific reports10
22022Loss of PP4 contributes to diesel exhaust particles-induced epithelial barrier integrity disruption and alarmins releaseYang, Feng-Ming; MENG-CHUN HU ; Weng, Chih-Ming; Chuang, Hsiao-Chi; Lan, Yu-Ting; Su, Bing-Hua; Heo, Kyung-Sun; Kuo, Han-PinAllergy12
32022HSD3B1 Expression Is Upregulated by Interleukin 4 in HT-29 Colon Cancer Cells via Multiple Signaling PathwaysChen, Hsin-Mei; Hung, Pei-Yu; Chen, Chih-Hung; Yu, Yu-Jhen; Syu, Ming-Shan; MENG-CHUN HU International journal of molecular sciences00
42022PEP-sNASP Peptide Alleviates LPS-Induced Acute Lung Injury Through the TLR4/TRAF6 AxisWu, Yu-Chih; Hsu, Sung-Po; MENG-CHUN HU ; Lan, Yu-Ting; Yeh, Edward T H; Yang, Feng-MingFrontiers in medicine33
52021Regulation of ClC-2 Chloride Channel Proteostasis by Molecular Chaperones: Correction of Leukodystrophy-Associated DefectFu, Ssu-Ju; MENG-CHUN HU ; Hsiao, Cheng-Tsung; Cheng, An-Ting; Chen, Tsung-Yu; Jeng, Chung-Jiuan; CHIH-YUNG TANG International journal of molecular sciences00
62020CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and LeukodystrophyFu, Ssu-Ju; MENG-CHUN HU ; Peng, Yi-Jheng; Fang, Hsin-Yu; Hsiao, Cheng-Tsung; Chen, Tsung-Yu; Jeng, Chung-Jiuan; CHIH-YUNG TANG Cells1211
72019Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolismLai T.-C.; MENG-CHUN HU Scientific Reports108
82018Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cellsNeirijnck Y.; Calvel P.; Kilcoyne K.R.; K?hne F.; St?vant I.; Griffeth R.J.; Pitetti J.-L.; Andric S.A.; MENG-CHUN HU ; Pralong F.; Smith L.B.; Nef S.FASEB Journal3126
92017Proximal GATA-binding sites are essential for human HSD3B1 gene transcription in the placentaLai T.-C.; Li H.-F.; Li Y.-S.; Hung P.-Y.; MING-KWANG SHYU ; MENG-CHUN HU Scientific Reports88
102017Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cellsLan H.-C.; Wu K.-Y.; Lin I.-W.; Yang Z.-J.; Chang A.-A.; MENG-CHUN HU Chemosphere4944
112017Ubiquitin ligase RNF138 promotes episodic ataxia type 2-associated aberrant degradation of human Cav2.1 (P/Q-type) calcium channelsFu S.-J.; Jeng C.-J.; Ma C.-H.; Peng Y.-J.; Lee C.-M.; Fang Y.-C.; Lee Y.-C.; SUNG-CHUN TANG ; MENG-CHUN HU ; CHIH-YUNG TANG 54
122016Phenotypic analysis of mice with steroid deficiencyEl Hadj N.B.; MENG-CHUN HU ; HSUEH-PING CHU ; Wang L.C.-K.; Chung B.-C.Genetically Engineered Mice Handbook0
132015A calreticulin-dependent nuclear export signal is involved in the regulation of liver receptor homologue-1 protein foldingYang F.-M.; Feng S.-J.; Lai T.-C.; MENG-CHUN HU Biochemical Journal77
142015The cullin 4A/B-DDB1-cereblon E3 ubiquitin ligase complex mediates the degradation of CLC-1 chloride channelsChen Y.-A.; Peng Y.-J.; MENG-CHUN HU ; Huang J.-J.; Chien Y.-C.; Wu J.-T.; Chen T.-Y.; CHIH-YUNG TANG Scientific Reports4848
152014Local anesthetics induce apoptosis in human breast tumor cellsChang Y.-C.; Liu C.-L.; Chen M.-J.; Hsu Y.-W.; Chen S.-N.; Lin C.-H.; Chen C.-M.; Yang F.-M.; MENG-CHUN HU Anesthesia and Analgesia104103
162014Steroidogenic cytochrome P450 gene CYP11A1: Functions and regulationShih M.M.-C.; Hsu H.-J.; Lan H.-C.; Weng J.-H.; Chien Y.; MENG-CHUN HU ; Chung B.-C.Fifty Years of Cytochrome P450 Research20
172014Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogen-activated protein kinase pathwayChang Y.-C.; Hsu Y.-C.; Liu C.-L.; Huang S.-Y.; MENG-CHUN HU ; Cheng S.-P.PLoS ONE11185
182012Feedback Control of Adrenal Steroidogenesis via H2O2-Dependent, Reversible Inactivation of Peroxiredoxin III in MitochondriaKil I.S.; Lee S.K.; Ryu K.W.; Woo H.A.; MENG-CHUN HU ; Bae S.H.; Rhee S.G.Molecular Cell142126
192011Regulation of steroid production: Analysis of Cyp11a1 promoterShih M.C.M.; Chiu Y.-N.; MENG-CHUN HU ; Guo I.-C.; Chung B.-C.Molecular and Cellular Endocrinology7668
202011Differential regulation of the human CYP11A1 promoter in mouse brain and adrenalsChiang Y.-F.; Lin H.-T.; Hu J.-W.; Tai Y.-C.; Lin Y.-C.; MENG-CHUN HU Journal of Cellular Physiology108
212011Identification of two functional nuclear localization signals mediating nuclear import of liver receptor homologue-1Yang F.-M.; Lin Y.-C.; MENG-CHUN HU Cellular and Molecular Life Sciences99
222010Docosahexaenoic acid induces proteasome-dependent degradation of estrogen receptor α and inhibits the downstream signaling target in MCF-7 breast cancer cellsLu I.-F.; Hasio A.-C.; MENG-CHUN HU ; Yang F.-M.; HUI-MIN SU Journal of Nutritional Biochemistry2523
232009Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cellsYang F.-M.; Pan C.-T.; Tsai H.-M.; Chiu T.-W.; Wu M.-L.; MENG-CHUN HU FEBS Journal3535
242009PIASy inhibits LRH-1-dependent CYP11A1 expression by competing for SRC-1 bindingHsieh H.-T.; Wang C.-H.; Wu M.-L.; Yang F.-M.; Tai Y.-C.; MENG-CHUN HU Biochemical Journal1413
252007Human CYP11A1 promoter drives Cre recombinase expression in the brain in addition to adrenals and gonadsWu, Hsu-Shui; Lin, Hui-Ting; Wang, Chi-Kuang Leo; Chiang, Yen-Feng; HSUEH-PING CHU ; MENG-CHUN HU Genesis1312
262007Transcriptional regulation of human CYP11A1 in gonads and adrenalsGuo I.-C.; Shih M.-C.; Lan H.-C.; Hsu N.-C.; MENG-CHUN HU ; Chung B.-C.Journal of Biomedical Science3936
272006Steroidogenesis in zebrafish and mouse modelsHsu H.-J.; Hsu N.-C.; MENG-CHUN HU ; Chung B.-C.Molecular and Cellular Endocrinology3629
282006Erratum: Steroid deficiency syndromes in mice with targeted disruption of Cyp11a1 (Molecular Endocrinology (2000) 16 (1943-1950))MENG-CHUN HU Molecular Endocrinology060
292004Function of Cyp11a1 in animal modelsMENG-CHUN HU ; Hsu H.-J.; Guo I.-C.; Chung B.-C.Molecular and Cellular Endocrinology6157
302003Transcriptional regulation of CYP11A1Guo I.-C.; MENG-CHUN HU ; Chung B.-C.Journal of Biomedical Science4438
312002Steroid deficiency syndromes in mice with targeted disruption of Cyp11a1MENG-CHUN HU ; Hsu, Nai-Chi; El Hadj, Noomen Ben; Pai, Chin-I; HSUEH-PING CHU ; Wang, Chi-Kuang Leo; Chung, Bon-ChuMolecular Endocrinology131109
322001Action of hormone responsive sequence in 2.3 kb promoter of CYP11A1Huang Y.-Y.; MENG-CHUN HU ; Hsu N.-C.; Wang C.-K.L.; Chung B.-C.Molecular and Cellular Endocrinology2017
332001Regulation of steroidogenesis in transgenic mice and zebrafishMENG-CHUN HU ; Chiang E.F.-L.; Tong S.-K.; Lai W.; Hsu N.-C.; Wang L.C.-K.; Chung B.-C.Molecular and Cellular Endocrinology4033
342001Functions of the upstream and proximal steroidogenic factor 1 (SF-1)-binding sites in the CYP11A1 promoter in basal transcription and hormonal responseMENG-CHUN HU ; Hsu N.-C.; Pai C.-I.; Leo Wang C.-K.; Chung B.-C.Molecular Endocrinology9793
352000Erratum: Tissue-specific, hormonal, and developmental regulation of SCC-LacZ expression in transgenic mice leads to adrenocortical zone characterization (Endocrinology (1999) 140 (5609-5618))MENG-CHUN HU ; Chou S.-J.; Huang Y.-Y.; Hsu N.-C.; Li H.; Chung B.-C.Endocrinology0
361999Tissue-specific, hormonal, and developmental regulation of SCC-LacZ expression in transgenic mice leads to adrenocortical zone characterizationMENG-CHUN HU ; Chou S.-J.; Huang Y.-Y.; Hsu N.-C.; Li H.; Chung B.-C.Endocrinology5453
371997Adenovirus E1B 19K protein is required for efficient DNA replication in U937 cellsMENG-CHUN HU ; Hsu M.-T.Virology1010
381996Function and membrane topology of wild-type and mutated cytochrome P-450c21MENG-CHUN HU ; LI-CHUNG HSU ; Hsu N.-C.; Chung B.-C.Biochemical Journal2018
391995Structure and expression of the CYP21 (p450c21, steroid 21-hydroxylase) gene with respect to its deficiencyChung B.-C.; MENG-CHUN HU ; Guzov V.M.; Wu D.-A.Endocrine Research1210
401993The N-terminal hydrophobic domain of P450c21 is required for membrane insertion and enzyme stabilityHsu L.-C.; MENG-CHUN HU ; Cheng H.-C.; Lu J.-C.; Chung B.-C.Journal of Biological Chemistry2828
411992Structure and Function of P450C21LI-CHUNG HSU ; MENG-CHUN HU ; Chung, Bon ChuJournal of Basic and Clinical Physiology and Pharmacology10
421992Amplification of P450c21 expression in cultured mammalian cellsRicketts M.H.; Chiao E.; MENG-CHUN HU ; Chung B.-c.Biochemical and Biophysical Research Communications76
431991Expression and Functional Study of Wild-Type and Mutant Human Cytochrome P450c21 in Saccharomyces cerevisiaeWu D.-A.; MENG-CHUN HU ; Chung B.-C.DNA and Cell Biology2624
441991Regulated expression of cytochrome P-450scc (cholesterol-side-chain cleavage enzyme) in cultured cell lines detected by antibody against bacterially expressed human proteinMENG-CHUN HU ; Guo I.-C.; Lin J.-H.; Chung B.-C.Biochemical Journal6461
451990Expression of human 21-hydroxylase (P450c21) in bacterial and mammalian cells: A system to characterize normal and mutant enzymesMENG-CHUN HU ; Chung B.-C.Molecular Endocrinology3732
461990A missense mutation of Ile172 → Asn or Arg356 → Trp causes steroid 21-hydroxylase deficiencyChiou S.-H.; MENG-CHUN HU ; CHung B.Journal of Biological Chemistry135136
471990An in vitro transcription termination system to analyze chloroplast promoters: identification of multiple promoters for the spinach atpB geneChen L.-J.; Rogers S.A.; Bennett D.C.; MENG-CHUN HU ; Orozco Jr. E.M.Current Genetics2022
481989The 5′-region of the P450XIA1 (P450scc) gene contains a basal promoter and an adrenal-specific activating domainChung B.-c.; MENG-CHUN HU ; Lai C.-C.; Lin C.-H.Biochemical and Biophysical Research Communications2932