Publications


Results 1-56 of 56 (Search time: 0.014 seconds).

Issue DateTitleAuthor(s)SourcescopusWOSFulltext/Archive link
12023Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma CellsHsu, Ya-Fen; Kung, Fan-Lu; Huang, Tzu-En; Deng, Yi-Ning; JIH-HWA GUH ; Marchetti, Paolo; Marchesi, Elena; Perrone, Daniela; Navacchia, Maria Luisa; LIH-CHING HSU Molecules (Basel, Switzerland)
22022Discovery of New Glucose Uptake Inhibitors as Potential Anticancer Agents by Non-Radioactive Cell-Based AssaysHung, Hsueh-Chih; Li, Li-Cheng; JIH-HWA GUH ; FAN-LU KUNG ; LIH-CHING HSU Molecules (Basel, Switzerland)11
32022The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling PathwaysWeng, Hao-Cheng; Sung, Chieh-Ju; Hsu, Jui-Ling; Leu, Wohn-Jenn; JIH-HWA GUH ; FAN-LU KUNG ; LIH-CHING HSU Frontiers in pharmacology54
42021Characterization of a fluorescent glucose derivative 1-NBDG and its application in the identification of natural SGLT1/2 inhibitorsKao, Ting-Yu; Wu, Hwa-Wei; SHOEI-SHENG LEE ; PI-HUI LIANG ; JIH-HWA GUH ; LIH-CHING HSU Journal of food and drug analysis22
52021Targeting Colorectal Cancer with Conjugates of a Glucose Transporter Inhibitor and 5-FluorouracilChang C.-K.; Chiu P.-F.; Yang H.-Y.; Juang Y.-P.; Lai Y.-H.; Lin T.-S.; LIH-CHING HSU ; LINDA CHIA-HUI YU ; Liang P.-H.Journal of Medicinal Chemistry1312
62020Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism StudiesLeu W.-J.; Chu J.-C.; Hsu J.-L.; Du C.-M.; Jiang Y.-H.; LIH-CHING HSU ; Huang W.-J.; JIH-HWA GUH Molecules (Basel, Switzerland)66
72020Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest SignalingHsu J.-L.; Leu W.-J.; LIH-CHING HSU ; Ho C.-H.; SHIH-PING LIU ; JIH-HWA GUH Frontiers in Oncology77
82020Discovery of novel agents on spindle assembly checkpoint to sensitize vinorelbine-induced mitotic cell death against human non-small cell lung cancersChang Y.-C.; Tseng Y.-L.; Leu W.-J.; Du C.-M.; Jiang Y.-H.; LIH-CHING HSU ; Hsu J.-L.; Hou D.-R.; JIH-HWA GUH International Journal of Molecular Sciences11
92020Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma CellsHuang T.-E.; Deng Y.-N.; Hsu J.-L.; Leu W.-J.; Marchesi E.; Capobianco M.L.; Marchetti P.; Navacchia M.L.; JIH-HWA GUH ; Perrone D.; LIH-CHING HSU Frontiers in Pharmacology1817
102020The (+)-brevipolide H displays anticancer activity against human castration-resistant prostate cancer: The role of oxidative stress and Akt/mTOR/p70S6K dependent pathways in G1 checkpoint arrest and apoptosisSheng Y.-H.; Leu W.-J.; Chen C.-N.; Hsu J.-L.; Liu Y.-T.; LIH-CHING HSU ; Hou D.-R.; JIH-HWA GUH Molecules44
112019Phosphodiesterase type 5 (PDE5) inhibitors sensitize topoisomerase II inhibitors in killing prostate cancer through PDE5-independent impairment of HR and NHEJ DNA repair systemsChang J.-F.; Hsu J.-L.; Sheng Y.-H.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Chan M.-L.; LIH-CHING HSU ; SHIH-PING LIU ; JIH-HWA GUH Frontiers in Oncology1011
122019The combination of MK-2206 and WZB117 exerts a synergistic cytotoxic effect against breast cancer cellsLi Y.-L.; Weng H.-C.; Hsu J.-L.; SHU-WHA LIN ; JIH-HWA GUH ; LIH-CHING HSU Frontiers in Pharmacology2221
132019Dihydroartemisinin–Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer ActivityMarchesi E.; Chinaglia N.; Capobianco M.L.; Marchetti P.; Huang T.-E.; Weng H.-C.; JIH-HWA GUH ; LIH-CHING HSU ; Perrone D.; Navacchia M.L.ChemMedChem1515
142018Para-toluenesulfonamide induces anti-tumor activity through Akt-dependent and -independent mTOR/p70S6K pathway: Roles of lipid raft and cholesterol contentsHsu J.-L.; Leu W.-J.; LIH-CHING HSU ; SHIH-PING LIU ; Zhong N.-S.; JIH-HWA GUH Frontiers in Pharmacology917
152018Traversal of the Blood-Brain Barrier by Cleavable l -Lysine Conjugates of ApigeninWong T.-Y.; Tsai M.-S.; LIH-CHING HSU ; SHU-WHA LIN ; Liang P.-H.Journal of Agricultural and Food Chemistry46
162017Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathwaysChan M.-L.; Yu C.-C.; Hsu J.-L.; Leu W.-J.; Chan S.-H.; LIH-CHING HSU ; SHIH-PING LIU ; Ivantcova P.M.; Dogan ?.; Br?se S.; Kudryavtsev K.V.; JIH-HWA GUH Oncotarget88
172017Using precursor ion scan of 184 with liquid chromatography-electrospray ionization-tandem mass spectrometry for concentration normalization in cellular lipidomic studiesChao H.-C.; GUAN-YUAN CHEN ; LIH-CHING HSU ; Liao H.-W.; Yang S.-Y.; Wang S.-Y.; Li Y.-L.; SUNG-CHUN TANG ; Tseng Y.J.; YUFENG JANE TSENG 2220
182016Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathwaysLeu W.-J.; Swain S.P.; Chan S.-H.; Hsu J.-L.; SHIH-PING LIU ; Chan M.-L.; Yu C.-C.; LIH-CHING HSU ; Chou Y.-L.; Chang W.-L.; Hou D.-R.; JIH-HWA GUH Oncotarget1414
192016Gain-of-function p53 mutant with 21-bp deletion confers susceptibility to multidrug resistance in MCF-7 cellsTsou S.-H.; Hou M.-H.; LIH-CHING HSU ; Chen T.-M.; YEN-HUI CHEN International Journal of Molecular Medicine1412
202016Downregulation of COMMD1 by MIR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cellsYeh D.-W.; Chen Y.-S.; Lai C.-Y.; Liu Y.-L.; Lu C.-H.; Lo J.-F.; Chen L.; LIH-CHING HSU ; Luo Y.; Xiang R.; Chuang T.-H.Cell Death and Differentiation3130
212016Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growthLai W.-T.; Cheng K.-L.; Baruchello R.; Rondanin R.; Marchetti P.; Simoni D.; Lee R.M.; JIH-HWA GUH ; LIH-CHING HSU Biochemical Pharmacology77
222016A novel hybrid drug between two potent anti-tubulin agents as a potential prolonged anticancer approachMarchetti P.; Pavan B.; Simoni D.; Baruchello R.; Rondanin R.; Mischiati C.; Feriotto G.; Ferraro L.; LIH-CHING HSU ; Lee R.M.; Dalpiaz A.European Journal of Pharmaceutical Sciences77
232015Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - A crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activationChang W.-L.; LIH-CHING HSU ; Leu W.-J.; Chen C.-S.; JIH-HWA GUH Oncotarget3734
242015Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insultChan M.-L.; Liang J.-W.; LIH-CHING HSU ; Chang W.-L.; SHOEI-SHENG LEE ; JIH-HWA GUH Naunyn-Schmiedeberg's Archives of Pharmacology3832
252015Effects of lipopolysaccharide on the expression of plasma membrane monoamine transporter (PMAT) at the blood-brain barrier and its implications to the transport of neurotoxinsWu K.-C.; Lu Y.-H.; Peng Y.-H.; LIH-CHING HSU ; Lin C.-J.Journal of Neurochemistry2115
262015Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathwayHo C.-H.; Hsu J.-L.; SHIH-PING LIU ; LIH-CHING HSU ; Chang W.-L.; Chao C.C.-K.; JIH-HWA GUH Prostate1414
272015Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastomaHsu J.-L.; Liu F.-L.; LIH-CHING HSU ; Chang H.-S.; Leu W.-J.; Yu C.-C.; Chang W.-L.; Chen I.-S.; FAN-LU KUNG ; JIH-HWA GUH Oncotarget65
282014Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulationWang W.-T.; Chen Y.-H.; Hsu J.-L.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Ho Y.-F.; LIH-CHING HSU ; JIH-HWA GUH Naunyn-Schmiedeberg's Archives of Pharmacology2625
292014The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cellsLin Y.-H.; Chen B.Y.-H.; Lai W.-T.; Wu S.-F.; JIH-HWA GUH ; ANN-LII CHENG ; LIH-CHING HSU Naunyn-Schmiedeberg's Archives of Pharmacology3432
302014Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycleLeu W.-J.; Chang H.-S.; Chan S.-H.; Hsu J.-L.; Yu C.-C.; LIH-CHING HSU ; Chen I.-S.; JIH-HWA GUH PLoS ONE2624
312014The K898E germline variant in the PP1-binding motif of BRCA1 causes defects in DNA RepairChen B.Y.-H.; Huang C.-H.; Lin Y.-H.; Huang C.-C.; Deng C.-X.; LIH-CHING HSU Scientific Reports89
322014A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathwayHsu J.-L.; SHIH-PING LIU ; Lee C.-C.; LIH-CHING HSU ; Ho Y.-F.; Huang H.-S.; JIH-HWA GUH Naunyn-Schmiedeberg's Archives of Pharmacology1312
332013Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulationYu C.-C.; Wu P.-J.; Hsu J.-L.; Ho Y.-F.; LIH-CHING HSU ; Chang Y.-J.; Chang H.-S.; Chen I.-S.; JIH-HWA GUH Prostate2422
342013Synthesis and biological evaluation of novel C-aryl D-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitorsLin T.-S.; Liw Y.-W.; Song J.-S.; Hsieh T.-C.; Yeh H.-W.; LIH-CHING HSU ; Lin C.-J.; Wu S.-H.; Liang P.-H.Bioorganic and Medicinal Chemistry1310
352013Development of a novel non-radioactive cell-based method for the screening of SGLT1 and SGLT2 inhibitors using 1-NBDGChang H.-C.; Yang S.-F.; Huang C.-C.; Lin T.-S.; PI-HUI LIANG ; Lin C.-J.; LIH-CHING HSU Molecular BioSystems1616
362013Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na+/K+-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascadesChan S.-H.; Leu W.-J.; LIH-CHING HSU ; Chang H.-S.; Hwang T.-L.; Chen I.-S.; Chen C.-S.; JIH-HWA GUH Biochemical Pharmacology1615
372012Development of hemiasterlin derivatives as potential anticancer agents that inhibit tubulin polymerization and synergize with a stilbene tubulin inhibitorLIH-CHING HSU ; Durrant D.E.; Huang C.-C.; Chi N.-W.; Baruchello R.; Rondanin R.; Rullo C.; Marchetti P.; Grisolia G.; Simoni D.; Lee R.M.Investigational New Drugs1410
382012Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repairHsu J.-L.; Leong P.-K.; Ho Y.-F.; LIH-CHING HSU ; Lu P.-H.; Chen C.-S.; JIH-HWA GUH Cancer Letters2217
392012Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathwayHsu J.-L.; Ho Y.-F.; TSAI-KUN LI ; Chen C.-S.; LIH-CHING HSU ; JIH-HWA GUH Biochemical Pharmacology1816
402008A PP1-binding motif present in BRCA1 plays a role in its DNA repair functionYu Y.-M.; Pace S.M.; Allen S.R.; Deng C.-X.; LIH-CHING HSU International Journal of Biological Sciences2323
412007Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinomaParikh R.A.; White J.S.; Huang X.; Schoppy D.W.; Baysal B.E.; Baskaran R.; Bakkenist C.J.; Saunders W.S.; LIH-CHING HSU ; Romkes M.; Gollin S.M.Genes Chromosomes and Cancer6864
422007Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: Implications for pathogenesis of ovarian cancerWilcox C.B.; Feddes G.O.; Willett-Brozick J.E.; LIH-CHING HSU ; DeLoia J.A.; Baysal B.E.BMC Cancer3738
432007Identification and functional characterization of a PP1-binding site in BRCA1LIH-CHING HSU Biochemical and Biophysical Research Communications1616
442006Gene amplification and overexpression of protein phosphatase 1α in oral squamous cell carcinoma cell linesLIH-CHING HSU ; Huang X.; Seasholtz S.; Potter D.M.; Gollin S.M.Oncogene3937
452005Centrosome abnormalities in ovarian cancerLIH-CHING HSU ; Kapali M.; DeLoia J.A.; Gallion H.H.International Journal of Cancer4442
462004The HPV16 E6/E7 oncogene sensitizes human ovarian surface epithelial cells to low-dose but not high-dose 5-FU and 5-FUdRLIH-CHING HSU ; Lee R.M.; White R.L.Biochemical and Biophysical Research Communications44
472002Regulation of BRCA1 phosphorylation by interaction with protein phosphatase 1αLiu Y.; Virshup D.M.; White R.L.; LIH-CHING HSU Cancer Research3130
482001Identification of a γ-tubulin-binding domain in BRCA1LIH-CHING HSU ; Doan T.P.; White R.L.Cancer Research116109
491998Mapping of 55 new rat microsatellite markers from chromosome-specific librariesShepel L.A.; Lan H.; Brasic G.M.; Gheen M.E.; LIH-CHING HSU ; Haag J.D.; Gould M.N.Mammalian Genome168
501998BRCA1 is associated with the centrosome during mitosisLIH-CHING HSU ; White R.L.Proceedings of the National Academy of Sciences of the United States of America271270
511996Allelic imbalance in mammary carcinomas induced by either 7,12-dimethylbenz[a]anthracene or ionizing radiation in rats carrying genes conferring differential susceptibilities to mammary carcinogenesisHaag J.D.; LIH-CHING HSU ; Newton M.A.; Gould M.N.Molecular Carcinogenesis31
521994Genetic Identification of Mcs-1, a Rat Mammary Carcinoma Suppressor GeneLIH-CHING HSU ; Kennan W.S.; Shepel L.A.; Jacob H.J.; Szpirer C.; Szpirer J.; Lander E.S.; Gould M.N.Cancer Research6056
531994Bivariate flow karyotyping, sorting, and peak assignment of all rat chromosomesShepel L.A.; Morrissey L.W.; LIH-CHING HSU ; Gould M.N.Genomics2120
541993Cloning and Characterization of Overexpressed Genes in the Mammary Gland of Rat Strains Carrying the Mammary CarcinomaSuppressor (Mcs) GeneLIH-CHING HSU ; Gould M.N.Cancer Research1313
551991Molecular cloning of copenhagen rat krev-1 and rap1b cdnas and study of their association with mammary tumor resistance in the copenhagen ratLIH-CHING HSU ; Gould M.N.Carcinogenesis13
561990Molecular cloning of rat krev-1 cdna and analysis of the mrna levels in normal and nmu-induced mammary carcinomasHong H.J.; LIH-CHING HSU ; Gould M.N.Carcinogenesis59