研究成果


第 1 到 51 筆結果，共 51 筆。

公開日期標題作者來源出版物scopusWOS全文
12023Ling Zhi-8, a fungal immunomodulatory protein in Ganoderma lucidum, alleviates CPT-11-induced intestinal injury via restoring claudin-1 expressionLi, Ju-Pi; CHING-LIANG CHU ; Chao, Wan-Ru; Yeh, Cheng-Siang; Lee, Yi-Ju; Chen, Dz-Chi; Yang, Shun-Fa; Chao, Yu-HuaAging
22022Increased HIF-1α expression in T cells and associated with enhanced Th17 pathway in systemic lupus erythematosusLiao, Hsiu-Jung; CHING-LIANG CHU ; Wang, Szu-Chieh; Lee, Hua-Yi; Wu, Chien-ShengJournal of the Formosan Medical Association
32022T Cell-Specific Deletion of TRAIL Receptor Reveals Its Critical Role for Regulating Pathologic T Cell Activation and Disease Induction in Experimental Autoimmune EncephalomyelitisChyuan, I-Tsu; CHING-LIANG CHU ; Hsu, Chia-Lang; Pan, Meng-Hsun; Liao, Hsiu-Jung; Wu, Chien-Sheng; PING-NING HSU Journal of Immunology1
42021The Enhancing Effect of Fungal Immunomodulatory Protein-Volvariella Volvacea (FIP-vvo) on Maturation and Function of Mouse Dendritic CellsLi, Ju-Pi; Lee, Yi-Pang; Ma, Jung-Chein; Liu, Betty-Revon; Hsieh, Nien-Tsu; Chen, Dz-Chi; CHING-LIANG CHU ; You, Ren-InLife22
52021Targeting the Tumor Microenvironment for Improving Therapeutic Effectiveness in Cancer Immunotherapy: Focusing on Immune Checkpoint Inhibitors and Combination TherapiesChyuan, I-Tsu; CHING-LIANG CHU ; PING-NING HSU Cancers2525
62021Prevention of dextran sulfate sodium-induced mouse colitis by the fungal protein Ling Zhi-8 via promoting the barrier function of intestinal epithelial cellsChen, Yu-Huan; Shin, Jenn-Yeu; Wei, Hsiu-Mei; Lin, Chi-Chien; LINDA CHIA-HUI YU ; Liao, Wei-Ting; Chen, Dz-Chi; CHING-LIANG CHU Food & function85
72020Tris DBA Ameliorates Accelerated and Severe Lupus Nephritis in Mice by Activating Regulatory T Cells and Autophagy and Inhibiting the NLRP3 InflammasomeWu, Chung-Yao; Hua, Kuo-Feng; CHING-LIANG CHU ; Yang, Shin-Ruen; Arbiser, Jack L; Yang, Sung-Sen; Lin, Yu-Chuan; Liu, Feng-Cheng; Yang, Shun-Min; Ka, Shuk-Man; Chen, AnnJournal of Immunology1718
82020Tyrosine kinase inhibitors modulate dendritic cell activity via confining c-Kit signaling and tryptophan metabolismCHING-LIANG CHU ; Lee, Yi-Pang; Pang, Cheng-Yoong; Lin, Huei-Ru; Chen, Chang-Shan; You, Ren-InInternational immunopharmacology1211
92020Compound K inhibits priming and mitochondria-associated activating signals of NLRP3 inflammasome in renal tubulointerstitial lesionsHsu, Wan-Han; Hua, Kuo-Feng; Tuan, Li-Heng; Tsai, Yu-Ling; Chu, Lichieh Julie; Lee, Yu-Chieh; Wong, Wei-Ting; Lee, Sheau-Long; Lai, Jenn-Haung; CHING-LIANG CHU ; Ho, Ling-Jun; Chiu, Hsiao-Wen; Hsu, Yu-Juei; Chen, Cheng-Hsu; Ka, Shuk-Man; Chen, AnnNephrology Dialysis Transplantation2120
102020A recently described type 2 conventional dendritic cell (cDC2) subset mediates inflammationJenn-Yeu Shin; Chen-Yu Wang; Chi-Chien Lin; CHING-LIANG CHU Cellular & Molecular Immunology1815
112019Accelerated and severe lupus nephritis benefits from M1, an active metabolite of ginsenoside, by regulating NLRP3 inflammasome and T cell functions in miceLin, Tsai Jung; Wu, Chung Yao; Tsai, Pei Yi; Hsu, Wan Han; Hua, Kuo Feng; CHING-LIANG CHU ; Lee, Yu Chieh; Chen, Ann; Lee, Sheau Long; Lin, Yi Jin; Hsieh, Chih Yu; Yang, Shin Ruen; Liu, Feng Cheng; Ka, Shuk ManFrontiers in Immunology2221
122019A Benzenoid 4,7-Dimethoxy-5-Methyl-L, 3-Benzodioxole from Antrodia cinnamomea Attenuates Dendritic Cell-Mediated Th2 Allergic ResponsesYou, Ren In; Lee, Yi Pang; Su, Ting Yi; Lin, Chi Chien; Chen, Chang Shan; CHING-LIANG CHU American Journal of Chinese Medicine54
132018Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activationChung, I-Che; Yuan, Sheng-Ning; OuYang, Chun-Nan; Lin, Hsin-Chung; Huang, Kuo-Yang; YU-JEN CHEN; Chung, An-Ko; CHING-LIANG CHU ; Ojcius, David M; Chang, Yu-Sun; Chen, Lih-ChyangCell death & disease2125
142018Gold lotion from citrus peel extract ameliorates imiquimod-induced psoriasis-like dermatitis in murineChi-Chien Lin; Jung-Ju Wu; Yi-Gen Pan; Ya-Hsuan Chao; Fang-Chu Lin; Ying-Ray Lee; CHING-LIANG CHU Journal of the Science of Food and Agriculture63
152017SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activationYou, Ren-In; CHING-LIANG CHU Cellular & molecular immunology44
162017IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and FibrosisChi, Hsi-Hua; Hua, Kuo-Feng; Lin, Yu-Chuan; CHING-LIANG CHU ; Hsieh, Chih-Yu; Hsu, Yu-Juei; Ka, Shuk-Man; Tsai, Yu-Ling; Liu, Feng-Cheng; Chen, AnnJournal of the American Society of Nephrology : JASN111109
172017FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic CellsPan, Yi-Gen; Yu, Yen-Ling; Lin, Chi-Chien; Lanier, Lewis L; CHING-LIANG CHU Frontiers in immunology1414
182016Inhibitory effect of clove methanolic extract and eugenol on dendritic cell functionsLin, CH; Lin, SH; Lin, CC; YI-CHING LIU; Chen, CJ; CHING-LIANG CHU ; Huang, HC; Lin, MKJOURNAL OF FUNCTIONAL FOODS88
192016Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitisChung, I-Che; OuYang, Chun-Nan; Yuan, Sheng-Ning; Li, Hsin-Pai; Chen, Jeng-Ting; Shieh, Hui-Ru; YU-JEN CHEN; Ojcius, David M; CHING-LIANG CHU ; Yu, Jau-Song; Chang, Yu-Sun; Chen, Lih-ChyangScientific Reports5758
202015Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritisLi, Yi-Rong; Chen, Der-Yuan; CHING-LIANG CHU ; Li, Shiming; Chen, Yu-Kuo; Wu, Chao-Ling; Lin, Chi-Chen Journal of Nutritional Biochemistry5749
212015CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 PathwayHuang, Juin-Hua; Lin, Ching-Yu; BETTY AN-YE WU-HSIEH ; Wu, Sheng-Yang; Chen, Wen-Yu; CHING-LIANG CHU ; Brown, Gordon D.; Chuu, Chih-Pin; Wu-Hsieh, Betty A.; Gaffen, Sarah L.PLoS Pathogens6861
222015The adjuvant effects of high-molecule-weight polysaccharides purified from Antrodia cinnamomea on dendritic cell function and DNA vaccinesLIN-CHI CHEN ; Pan, I-Hong; Li, Yi-Rong; Pan, Yi-Gen; Lin, Ming-Kuem; Lu, Yi-Huang; Wu, Hsin-Chieh; CHING-LIANG CHU PloS ONE3862
232014Formulated extract from multiple citrus peels impairs dendritic cell functions and attenuates allergic contact hypersensitivityLi, Shiming; Lin, Yi-Chin; Ho, Chi-Tang; Lin, Ping-Yi; Suzawa, Michiko; Wang, Hsin-Chieh; CHING-LIANG CHU ; Chen, Der-Yuan; LIN-CHI CHEN International Immunopharmacology1715
242014Co-caged gold nanoclusters and methyl motifs lead to detoxification of dendrimers and allow cytosolic access for siRNA transfectionChien, Chih-Te; Liu, Chia-Yeh; Wu, Zong-Wei; Chen, Pin-Jyun; CHING-LIANG CHU ; Lin, Shu-YiJournal of Materials Chemistry B910
252014Polysaccharides from Ganoderma formosanum function as a Th1 adjuvant and stimulate cytotoxic T cell response in vivoPi, Chia-Chen; CHING-LIANG CHU ; Lu, Chu-Ying; Zhuang, Yu-Jing; Wang, Cheng-Li; Yu, Yao-Hsuan; Wang, Hui-Yi; Lin, Chih-Chung; Chen, Chun-JenVaccine2721
262014Immunomodulation of phloretin by impairing dendritic cell activation and functionLin, Chi-Chen ; CHING-LIANG CHU ; Ng, Chin-Sheng; Lin, Ching-Yen; Chen, Der-Yuan; Pan, I. -Hong; Huang, Kao-JeanFood and Function3028
272013Myricetin attenuates lipopolysaccharidestimulated activation of mouse bone marrowderived dendritic cells through suppression of IKK/nf-kB and MAPK signalling pathwaysFu, R.-H.; Liu, S.-P.; CHING-LIANG CHU ; Lin, Y.-H.; Ho, Y.-C.; Chiu, S.-C.; Lin, W.-Y.; Shyu, W.-C.; Lin, S.-Z.Journal of the Science of Food and Agriculture3227
282013Clitocybe nuda activates dendritic cells and acts as A DNA vaccine adjuvantChen, M.-H.; Li, W.-S.; Lue, Y.-S.; CHING-LIANG CHU ; Pan, I.-H.; Ko, C.-H.; Chen, D.-Y.; Lin, C.-H.; Lin, S.-H.; Chang, C.-P.; Lin, C.-C.Evidence-based Complementary and Alternative Medicine1712
292013Dextromethorphan inhibits activations and functions in dendritic cellsChen, D.-Y.; Song, P.-S.; Hong, J.-S.; CHING-LIANG CHU ; Pan, I.-H.; Chen, Y.-M.; Lin, C.-H.; Lin, S.-H.; Lin, C.-C.Clinical and Developmental Immunology1917
302013Immunomodulatory effect of marine cembrane-type diterpenoids on dendritic cellsLin, C.-Y.; Lu, M.-C.; Su, J.-H.; CHING-LIANG CHU ; Shiuan, D.; Weng, C.-F.; Sung, P.-J.; Huang, K.-J.Marine Drugs2621
312013Acetylcorynoline impairs the maturation of mouse bone marrow-derived dendritic cells via suppression of IκB kinase and mitogen-activated protein kinase activitiesFu, Ru-Huei; Wang, Yu-Chi; Liu, Shih-Ping; CHING-LIANG CHU ; Tsai, Rong-Tzong; Ho, Yu-Chen; Chang, Wen-Lin; Chiu, Shao-Chih; Harn, Horng-Jyh; Shyu, Woei-Cherng; Lin, Shinn-ZongPloS ONE2825
322012CD4+ T cells disarm or delete cytotoxic T lymphocytes under IL-17-polarizing conditionsTsai, Jy-Ping; Lee, Meng-Hua; Hsu, Shu-Ching; Chen, Mei-Yu; Liu, Shih-Jen; Chang, Joseph T; Liao, Chun-Ta; Cheng, Ann-Joy; Chong, Pele; CHING-LIANG CHU ; Shen, Chia-Rui; Chen, Hsin-WeiJournal of Immunology1713
332012The immunomodulatory activity of meningococcal lipoprotein Ag473 depends on the conformation made up of the lipid and protein moietiesCHING-LIANG CHU ; Yu, Yen-Ling; Kung, Yueh-Chen; Liao, Pei-Yu; Liu, Ko-Jiunn; Tseng, Yen-Tzu; Lin, Yuan-Chuen; Hsieh, Steve Shih-Yang; Chong, Pele Choi-Sing; Yang, Chiou-YingPloS ONE109
342012Extracellular polysaccharides produced by Ganoderma formosanum stimulate macrophage activation via multiple pattern-recognition receptorsWang, Cheng-Li; Lu, Chiu-Ying; Pi, Chia-Chen; Zhuang, Yu-Jing; CHING-LIANG CHU ; Liu, Wen-Hsiung; Chen, Chun-JenBmc Complementary and Alternative Medicine3739
352011Lipopolysaccharide-stimulated activation of murine DC2.4 cells is attenuated by n-butylidenephthalide through suppression of the NF-κB pathwayFu, R.-H.; Hran, H.-J.; CHING-LIANG CHU ; Huang, C.-M.; Liu, S.-P.; Wang, Y.-C.; Lin, Y.-H.; Shyu, W.-C.; Lin, S.-Z.Biotechnology Letters3634
362011A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cellsLin, C.-C.; Yu, Y.-L.; Shih, C.-C.; Liu, K.-J.; Ou, K.-L.; Hong, L.-Z.; Chen, J.D.C.; CHING-LIANG CHU Cancer Immunology, Immunotherapy5647
372011A novel adjuvant Ling Zhi-8 for cancer DNA vaccinesCHING-LIANG CHU ; Chen, D.-C.; Lin, C.-C.Human Vaccines00
382011RNA interference-mediated silencing of Foxo3 in antigen-presenting cells as a strategy for the enhancement of DNA vaccine potencyWang, S.-T.; Chang, C.-C.; Yen, M.-C.; Tu, C.-F.; CHING-LIANG CHU ; Peng, Y.-T.; Chen, D.-Y.; Lan, J.-L.; Lin, C.-C.Gene Therapy1818
392011Kaempferol from Semen cuscutae attenuates the immune function of dendritic cellsLin, M.-K.; Yu, Y.-L.; Chen, K.-C.; Chang, W.-T.; Lee, M.-S.; Yang, M.-J.; Cheng, H.-C.; Liu, C.-H.; Chen, D.-C.; CHING-LIANG CHU Immunobiology7366
402010Immunosuppressive effect of quercetin on dendritic cell activation and functionHuang, R.-Y.; Yu, Y.-L.; Cheng, W.-C.; Ouyang, C.-N.; Fu, E.; CHING-LIANG CHU Journal of Immunology161134
412010Myeloid cells, BAFF, and IFN-γ establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient miceScapini, P.; Hu, Y.; CHING-LIANG CHU ; Migone, T.-S.; Defranco, A.L.; Cassatella, M.A.; Lowell, C.A.Journal of Experimental Medicine9288
422010Ameliorative effect of quercetin on the destruction caused by experimental periodontitis in ratsCheng, W.-C.; Huang, R.-Y.; Chiang, C.-Y.; Chen, J.-K.; Liu, C.-H.; CHING-LIANG CHU ; Fu, E.Journal of Periodontal Research4638
432010Dendritic cell activation by recombinant hemagglutinin proteins of H1N1 and H5N1 influenza A virusesLiu, W.-C.; Lin, S.-C.; Yu, Y.-L.; CHING-LIANG CHU ; Wu, S.-C.Journal of Virology3130
442009The expanding roles of ITAM adapters FcRγ and DAP12 in myeloid cellsHamerman, J.A.; Ni, M.; Killebrew, J.R.; CHING-LIANG CHU ; Lowell, C.A.Immunological Reviews9187
452008Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRγCHING-LIANG CHU ; Yu, Y.-L.; Shen, K.-Y.; Lowell, C.A.; Lanier, L.L.; Hamerman, J.A.European Journal of Immunology5554
462005The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturationCHING-LIANG CHU ; Lowell, C.A.Journal of Immunology
472005The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-BZhang, H.; Meng, F.; CHING-LIANG CHU ; Takai, T.; Lowell, C.A.Immunity8989
482002The mechanism underlying T cell help for induction of an antigen-specific in vivo humoral immune response to intact Streptococcus pneumoniae is dependent on the type of antigenWu, Z.-Q.; Shen, Y.; Khan, A.Q.; CHING-LIANG CHU ; Riese, R.; Chapman, H.A.; Kanagawa, O.; Snapper, C.M.Journal of Immunology
492001Regulation of CD1 function and NK1.1<sup>+</sup> T cell selection and maturation by cathepsin SRiese, Richard J.; Shi, Guo Ping; Villadangos, Jose; Stetson, Daniel; Driessen, Christoph; Lennon-Dumenil, Ana Maria; CHING-LIANG CHU ; Naumov, Yuri; Behar, Samuel M.; Ploegh, Hidde; Locksley, Richard; Chapman, Harold A.Immunity7871
501999IL-15 promotes survival but not effector function differentiation of CD8+ TCRalphabeta+ intestinal intraepithelial lymphocytesLai, Y G; Gelfanov, V; Gelfanova, V; Kulik, L; CHING-LIANG CHU ; Jeng, S W; Liao, N SJournal of Immunology5245
511999Differential effects of IL-2 and IL-15 on the death and survival of activated TCR gamma delta+ intestinal intraepithelial lymphocytesCHING-LIANG CHU ; Chen, S S; Wu, T S; Kuo, S C; Liao, N SJournal of immunology5045