研究成果


第 1 到 62 筆結果，共 62 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Administration mode matters for 5‐fluorouracil therapy: Physiologically based pharmacokinetic evidence for avoidance of myelotoxicity by continuous infusion but not intravenous bolusChao, Chih‐Jia; Gardner, Iain; CHUN-JUNG LIN ; KUN-HUEI YEH ; Lu, Wan‐Chen; Abduljalil, Khaled; YUNN-FANG HO British Journal of Clinical Pharmacology
22024Anticonvulsant effect of equilibrative nucleoside transporters 1 inhibitor in a mouse model of Dravet syndromeHo, Shih-Yin; I-CHUN CHEN ; WEN-CHE TSAI ; Chang, Kai-Chieh; CHUN-JUNG LIN ; Chern, Yijuang; HORNG-HUEI LIOU Hippocampus
32023Physiologically based mechanistic insight into differential risk of valproate hepatotoxicity between children and adults: A focus on ontogeny impactHuang, Yu-Ting; YEN-MING HUANG ; FAN-LU KUNG ; CHUN-JUNG LIN ; TUN JAO ; YUNN-FANG HO CPT: pharmacometrics & systems pharmacology1
42023The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with Brain Ischemia-ReperfusionChiang, Hui-Ling; Wu, Kuo-Chen; Chen, You-Yin; Ho, Chin-Jui; Wang, Han-Lin; Fu, Yu-Hua; Chen, Wen-Yu; CHUN-JUNG LIN Pharmaceutical research
52023Deletion of equilibrative nucleoside transporter 2 disturbs energy metabolism and exacerbates disease progression in an experimental model of Huntington's diseaseChen, Ching-Ya; Chou, Fang-Yi; Chang, Ya-Gin; Ho, Chin-Jui; Wu, Kuo-Chen; Hsu, Chia-Lin; Chern, Yijuang; CHUN-JUNG LIN Neurobiology of disease1
62023Equilibrative Nucleoside Transporter 1 is a Target to Modulate Neuroinflammation and Improve Functional Recovery in Mice with Spinal Cord InjuryChen, Kuan-Yu; Lu, Chiao-Shin; Pang, Cheng-Yoong; Ho, Chin-Jui; Wu, Kuo-Chen; Yang, Hsiu-Wei; Lai, Hsin-Lin; Chern, Yijuang; CHUN-JUNG LIN Molecular neurobiology
72022Ibuprofen treatment ameliorates memory deficits in rats with collagen-induced arthritis by normalizing aberrant MAPK/NF-κB and glutamatergic pathwaysZhang, Nai-You; Wang, Ting-Hsuan; Chou, Ching-Hsuan; Wu, Kuo-Chen; CHIA-RON YANG ; FAN-LU KUNG ; CHUN-JUNG LIN European Journal of Pharmacology3
82022The Asian Pharmacometrics Network: The historical background, establishment, objectives and roles, and recent activitiesAtsunori Kaibara; Ao Peng; Rujia Xie; YUNN-FANG HO ; CHUN-JUNG LIN ; Lai-San Tham; Surulivelrajan Mallayasamy; Korbtham Sathirakul; Yoke-Lin Lo; Manh Hung Tran; Van Toi Pham; Akhmad Kharis Nugroho; Khin Myo Oo; Bimal Kunwar; Uthpali Mannapperuma; Kimheang Ya; Muhammad Usman; Long Chiau Ming; Kyungsoo ParkCPT: Pharmacometrics and Systems Pharmacology11
92021Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritisLai, Po Hsuan; Wang, Ting Hsuan; Zhang, Nai You; Wu, Kuo Chen; JANE CHUNG-CHEN YAO ; CHUN-JUNG LIN Journal of Neuroinflammation1211
102021Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathyChang, Ching-Pang; Chang, Ya-Gin; Chuang, Pei-Yun; Nguyen, Thi Ngoc Anh; Wu, Kuo-Chen; Chou, Fang-Yi; Cheng, Sin-Jhong; Chen, Hui-Mei; Jin, Lee-Way; Carvalho, Kevin; Huin, Vincent; Buée, Luc; Liao, Yung-Feng; CHUN-JUNG LIN ; Blum, David; Chern, YijuangActa Neuropathologica Communications66
112021Amelioration of lipopolysaccharide-induced memory impairment in equilibrative nucleoside transporter-2 knockout mice is accompanied by the changes in glutamatergic pathwaysWu, Kuo-Chen; Lee, Chih-Yu; Chern, Yijuang; CHUN-JUNG LIN Brain, Behavior, and Immunity65
122020Equilibrative Nucleoside Transporters-1 Inhibitors Act as Anti-epileptic Agents by Inhibiting Glutamatergic TransmissionHo S.-Y.; Chen I.-C.; Chang K.-C.; Lin H.-R.; Tsai C.-W.; CHUN-JUNG LIN ; Liou H.-H.Frontiers in Neuroscience76
132020Deletion of equilibrative nucleoside transporter-2 protects against lipopolysaccharide-induced neuroinflammation and blood-brain barrier dysfunction in miceWu K.-C.; Lee C.-Y.; Chou F.-Y.; Chern Y.; CHUN-JUNG LIN Brain, Behavior, and Immunity2220
142019The regulation of drug-metabolizing enzymes and membrane transporters by inflammation: Evidences in inflammatory diseases and age-related disordersWu K.-C.; CHUN-JUNG LIN Journal of Food and Drug Analysis6054
152019Down-regulation of natural resistance-associated macrophage protein-1 (Nramp1) is associated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)/1-methyl-4-phenylpyridinium (MPP + )-induced α-synuclein accumulation and neurotoxicityWu K.-C.; HORNG-HUEI LIOU ; Lee C.-Y.; CHUN-JUNG LIN Neuropathology and Applied Neurobiology1512
162018Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s DiseaseLee, Chia-Chia; Chang, Ching-Pang; CHUN-JUNG LIN ; Lai, Hsing-Lin; Kao, Yu-Han; Cheng, Sin-Jhong; Chen, Hui-Mei; Liao, Yu-Ping; Faivre, Emilie; Buee, Luc; Blum, David; Fang, J.-M. ; HUI-MEI CHEN Molecular Neurobiology3535
172017Differential changes in the pharmacokinetics of statins in collagen-induced arthritis ratsCHUN-JUNG LIN Biochemical Pharmacology1715
182017Rifamycin SV MMX for the treatment of traveler’s diarrheaSHU-WEN LIN ; CHUN-JUNG LIN ; JYH-CHIN YANG Expert Opinion on Pharmacotherapy42
192017Targeting ENT1 and adenosine tone for the treatment of Huntington's diseaseKao, Yu-Han; Lin, Meng-Syuan; Chen, Chiung-Mei; Wu, Yih-Ru; Chen, Hui-Mei; Lai, Hsing-Lin; Chern, Yijuang; CHUN-JUNG LIN Human Molecular Genetics3129
202017The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload conditionWu K.-C.; HORNG-HUEI LIOU ; Kao Y.-H.; Lee C.-Y.; CHUN-JUNG LIN Neurobiology of Disease1211
212015Effects of lipopolysaccharide on the expression of plasma membrane monoamine transporter (PMAT) at the blood-brain barrier and its implications to the transport of neurotoxinsWu, Kuo-Chen; Lu, Ya-Hsuan; Peng, Yi-Hsuan; LIH-CHING HSU ; CHUN-JUNG LIN Journal of Neurochemistry2315
222015Biotransformed product, genistein 7-O-phosphate, enhances the oral bioavailability of genisteinWang, Shang-Ta; Fang, Ting-Fang; Hsu, Chen; Chen, Chia-Hao; CHUN-JUNG LIN ; NAN-WEI SU Journal of Functional Foods1718
232015Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged miceCHUN-JUNG LIN Journal of Cerebral Blood Flow and Metabolism3022
242015High-dose dual therapy is superior to standard first-line or rescue therapy for helicobacter pylori infectionJYH-CHIN YANG ; CHUN-JUNG LIN ; Wang H.-L.; Chen J.-D.; Kao J.Y.; CHIA-TUNG SHUN ; Lu C.-W.; BOR-RU LIN ; MING-JIUM SHIEH ; MING-CHU CHANG ; YU-TING CHANG ; SHU-CHEN WEI ; Lin L.-C.; Yeh W.-C.; Kuo J.-S.; CHIEN-CHIH TUNG ; Leong Y.-L.; Wang T.-H.; Wong J.-M.Clinical Gastroenterology and Hepatology153131
252014Treatment of Helicobacter pylori infection: Current status and future conceptsJYH-CHIN YANG ; Lu C.-W.; CHUN-JUNG LIN World Journal of Gastroenterology130119
262014Tamiphosphor monoesters as effective anti-influenza agentsChen, C.-L.; Lin, T.-C.; Wang, S.-Y.; Shie, J.-J.; Tsai, K.-C.; Cheng, Y.-S.E.; Jan, J.-T.; Lin, C.-J.; Fang, J.-M.; Wong, C.-H.; CHUN-JUNG LIN ; JIM-MIN FANG European Journal of Medicinal Chemistry2323
272013Synthesis and biological evaluation of novel C-aryl D-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitorsLin, Tzung-Sheng; Liw, Ya-Wen; Song, Jen-Shin; Hsieh, Tsung-Chih; Yeh, Hsien-Wei; LIH-CHING HSU ; CHUN-JUNG LIN ; Wu, Szu-Huei; PI-HUI LIANG Bioorganic and Medicinal Chemistry1311
282013Development of a novel non-radioactive cell-based method for the screening of SGLT1 and SGLT2 inhibitors using 1-NBDGChang, Hung-Chi; Yang, Su-Fu; Huang, Ching-Chun; Lin, Tzung-Sheng; PI-HUI LIANG ; CHUN-JUNG LIN ; LIH-CHING HSU Molecular BioSystems1716
292013Improved dissolution rate and oral bioavailability of lovastatin in red yeast rice productsChen C.-H.; JYH-CHIN YANG ; Uang Y.-S.; CHUN-JUNG LIN International Journal of Pharmaceutics6452
302012Hyperglycemia induced down-regulation of renal P-glycoprotein expressionCHUN-JUNG LIN European Journal of Pharmacology1612
312012Interaction between red yeast rice and CYP450 enzymes/P-glycoprotein and its implication for the clinical pharmacokinetics of lovastatinChen C.-H.; Uang Y.-S.; Wang S.-T.; JYH-CHIN YANG ; CHUN-JUNG LIN Evidence-based Complementary and Alternative Medicine3219
322012Differential inhibitory effects of proton pump inhibitors on the metabolism and antiplatelet activities of clopidogrel and prasugrelChen C.-H.; JYH-CHIN YANG ; Uang Y.-S.; CHUN-JUNG LIN Biopharmaceutics and Drug Disposition1915
332011MUC1 expression is elevated in severe preeclamptic placentas and suppresses trophoblast cell invasion via β1-integrin signalingMING-KWANG SHYU ; Chen C.-W.; NENG-YU LIN ; Liao W.-C.; CHI-HAU CHEN ; CHUN-JUNG LIN ; Huang H.-C.; Lee Jr. J.; Huang M.-J.; Tseng G.-F.; JIN-CHUNG SHIH ; CHIEN-NAN LEE ; FON-JOU HSIEH ; MIN-CHUAN HUANG Journal of Clinical Endocrinology and Metabolism2525
342011Hypoxia-mediated down-regulation of OCTN2 and PPARrα expression in human placentas and in BeWo cellsChang T-T.; MING-KWANG SHYU ; MIN-CHUAN HUANG ; Hsu C-C.; Yeh S-Y.; MEI-RU CHEN ; CHUN-JUNG LIN Molecular Pharmaceutics2322
352011Role of omeprazole dosage and cytochrome P450 2C19 genotype in patients receiving omeprazole-amoxicillin dual therapy for Helicobacter pylori eradicationJYH-CHIN YANG ; Wang H.-L.; Chern H.-D.; CHIA-TUNG SHUN ; BOR-RU LIN ; CHUN-JUNG LIN ; Wang T.-H.Pharmacotherapy4233
362011A new drug design targeting the adenosinergic system for huntington's diseaseHuang N.-K.; Lin J.-H.; Lin J.-T.; Lin C.-I.; Liu E.M.; CHUN-JUNG LIN ; Chen W.-P.; Shen Y.-C.; Chen H.-M.; Chen J.-B.; Lai H.-L.; Yang C.-W.; Chiang M.-C.; Wu Y.-S.; Chang C.; Chen J.-F.; Fang J.-M.; Lin Y.-L.; Chern Y.PLoS ONE7263
372010CYP2C19 genotypes in the pharmacokinetics/pharmacodynamics of proton pump inhibitor-based therapy of Helicobacter pylori infectionJYH-CHIN YANG ; CHUN-JUNG LIN Expert Opinion on Drug Metabolism and Toxicology4842
382010Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodentsCHUN-JUNG LIN ; Tai Y.; Huang M.-T.; Tsai Y.-F.; Hsu H.-J.; KAI-YUAN TZEN ; HORNG-HUEI LIOU Journal of Neurochemistry9780
392009Change in P-glycoprotein and caveolin protein expression in brain striatum capillaries in New Zealand Obese mice with type 2 diabetesWu, Kuo-Chen; Pan H.-J.; HSIANG-SHU YIN ; MEI-RU CHEN ; SHAO-CHUN LU ; CHUN-JUNG LIN Life Sciences2924
402009Regulation of Protein Expression and Function of OCTN2 in Forskolin-Induced Syncytialization in BeWo CellsHuang F.-D.; FAN-LU KUNG ; Tseng Y.-C.; MEI-RU CHEN ; Chan H.-S.; CHUN-JUNG LIN Placenta1512
412009Pharmacokinetic- pharmacodynamic analysis of the role of CYP2C19 genotypes in short-term rabeprazole-based triple therapy against Helicobacter pyloriJYH-CHIN YANG ; Yang Y.-F.; Uang Y.-S.; CHUN-JUNG LIN ; Wang T.-H.British Journal of Clinical Pharmacology1414
422009Aspect-ratio-dependent ultra-low reflection and luminescence of dry-etched Si nanopillars on Si substratePai, Y.-H.; Meng, F.-S.; Lin, C.-J.; Kuo, H.-C.; Hsu, S.-H.; Chang, Y.-C.; GONG-RU LIN ; Lin, Chun-Jung Nanotechnology1817
432008Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugsHung, Chin-Chuan; Chen, Chih-Chuan; CHUN-JUNG LIN ; HORNG-HUEI LIOU Pharmacogenetics and Genomics5449
442008Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapyCHUN-JUNG LIN ; Yen M.-F.; Hu O.Y.-P.; Lin M.-S.; Hsiong C.-H.; Hung, Chin-Chuan; HORNG-HUEI LIOU Pharmacotherapy76
452008Enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxiaYeh W.-L.; CHUN-JUNG LIN ; WEN-MEI FU Molecular Pharmacology128124
462008Characterization of Si nanorods by spectroscopic ellipsometry with efficient theoretical modelingHsu, S.-H.; Liu, E.-S.; Chang, Y.-C.; Hilfiker, J.N.; Kim, Y.D.; Kim, T.J.; Lin, C.-J.; Lin, G.-R.; GONG-RU LIN ; Lin, Chun-Jung Physica Status Solidi (A) Applications and Materials Science3331
472007Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cellsHORNG-HUEI LIOU ; Hsu, Hao-Jui; Tsai Y.-F.; Shih, Chin-Yu; Chang, Yu-Chia; CHUN-JUNG LIN Life Sciences1413
482007Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insultYeh T.-C.; Chiang P.-C.; TSAI-KUN LI ; Hsu J.-L.; CHUN-JUNG LIN ; Wang S.-W.; Peng C.-Y.; JIH-HWA GUH Biochemical Pharmacology123110
492007Interaction of flavonoids and intestinal facilitated glucose transportersCHUN-JUNG LIN Planta Medica4736
502007Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1α accumulation and VEGF expressionYeh W.-L.; Lu D.-Y.; CHUN-JUNG LIN ; Liou H.-C.; WEN-MEI FU Molecular Pharmacology131122
512006Inhibition of intestinal glucose uptake by aporphines and secoaporphinesCHUN-JUNG LIN ; Chen C.-H.; Liu F.-W.; Kang J.-J.; Chen C.-K.; Lee S.-L.; SHOEI-SHENG LEE Life Sciences1010
522005Complex haplotypic effects of the ABCB1 gene on epilepsy treatment responseHung, Chin-Chuan; Tai J.J.; CHUN-JUNG LIN ; MING-JEN LEE ; HORNG-HUEI LIOU Pharmacogenomics118102
532005Oxygen defect and Si nanocrystal dependent white-light and near-infrared electroluminescence of Si-implanted and plasma-enhanced chemical-vapor deposition-grown Si-rich SiO <inf>2</inf>Lin, G.-R.; Lin, C.-J.; Lin, C.-K.; Chou, L.-J.; Lin, Gong-Ru ; Lin, Chun-Jung ; GONG-RU LIN Journal of Applied Physics198195
542005Tissue distribution of arsenic species in rabbits after single and multiple parenteral administration of arsenic trioxide: Tissue accumulation and the reversibility after washout are tissue-selectiveCHUN-JUNG LIN ; MEI-HWAN WU ; Hsueh Y.-M.; Sun S.S.-M.; ANN-LII CHENG Cancer Chemotherapy and Pharmacology2318
552004Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphismsHung, Chin-Chuan; CHUN-JUNG LIN ; Chen, Chih-Chuan; Chang C.-J.; HORNG-HUEI LIOU Therapeutic Drug Monitoring11593
562004Interaction between Anticonvulsants and Human Placental Carnitine TransporterWu S.-P.; MING-KWANG SHYU ; HORNG-HUEI LIOU ; Gau C.-S.; CHUN-JUNG LIN Epilepsia3928
572003Time-dependent amplified pharmacokinetic and pharmacodynamic responses of rabeprazole in cytochrome P450 2C19 poor metabolizersCHUN-JUNG LIN ; JYH-CHIN YANG ; Uang Y.-S.; Chern H.-D.; Wang T.-H.Pharmacotherapy2116
582003Direct cardiac effects of As2O3 in rabbits: Evidence of reversible chronic toxicity and tissue accumulation of arsenicals after parenteral administrationMEI-HWAN WU ; CHUN-JUNG LIN ; Chen C.-L.; MING-JAI SU ; Sun S.S.-M.; ANN-LII CHENG Toxicology and Applied Pharmacology2823
591999Glycylsarcosine uptake in rabbit renal brush border membrane vesicles isolated from outer cortex or outer medulla: Evidence for heterogeneous distribution of oligopeptide transportersCHUN-JUNG LIN AAPS Journal
601999Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: Interaction of ACE inhibitors with high-affinity H+/peptide symporterCHUN-JUNG LIN Pharmaceutical Research3231
611998Noncompetitive inhibition of glycylsarcosine transport by quinapril in rabbit renal brush border membrane vesicles: Effect on high-affinity peptide transporterCHUN-JUNG LIN Journal of Pharmacology and Experimental Therapeutics
621996Intestinal absorption studies on peptide mimetic α-methyldopa prodrugsCHUN-JUNG LIN Journal of Pharmacy and Pharmacology