Publications

Results 1-57 of 57 (Search time: 0.008 seconds).

Issue DateTitleAuthor(s)SourcescopusWOSFulltext/Archive link
12021Glutamate transmission rather than cellular pacemaking propels excitatory-inhibitory resonance for ictogenesis in amygdalaWang G.-H.; Chou P.; Hsueh S.-W.; Yang Y.-C.; CHUNG-CHIN KUO Neurobiology of Disease2
22020Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disordersTai C.-H.; Pan M.-K.; Tseng S.-H.; Wang T.-R.; Chung-Chin Kuo Scientific Reports12
32020Author Correction: Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders (Scientific Reports, (2020), 10, 1, (8278), 10.1038/s41598-020-65211-w)Tai C.-H.; Pan M.-K.; Tseng S.-H.; Wang T.-R.; Chung-Chin Kuo Scientific Reports00
42020Desensitization of NMDA channels requires ligand binding to both GluN1 and GluN2 subunits to constrict the pore beside the activation gateChen Y.-S.; Tu Y.-C.; Lai Y.-C.; Liu E.; Yang Y.-C.; Chung-Chin Kuo Journal of Neurochemistry00
52020Inhibition of neuronal Na+ currents by lacosamide: Differential binding affinity and kinetics to different inactivated statesPeng Y.-S.; Wu H.-T.; Lai Y.-C.; Chen J.-L.; Yang Y.-C.; CHUNG-CHIN KUO Neuropharmacology3
62020Delta-Frequency Augmentation and Synchronization in Seizure Discharges and Telencephalic TransmissionChou P.; Wang G.-H.; Hsueh S.-W.; Yang Y.-C.; CHUNG-CHIN KUO iScience3
72019Temperature dependence of the biophysical mechanisms underlying the inhibition and enhancement effect of amiodarone on hERG channelssLo Y.-C.; Chung-Chin Kuo Molecular Pharmacology11
82019Anomalous enhancement of resurgent Na+ currents at high temperatures by SCN9A mutations underlies the episodic heat-enhanced pain in inherited erythromelalgiaHuang C.-W.; Lai H.-J.; Huang P.-Y.; Lee M.-J.; Chung-Chin Kuo Scientific Reports28
92016Neuronal firing patterns outweigh circuitry oscillations in parkinsonian motor controlPan M.-K.; Kuo S.-H.; Tai C.-H.; Liou J.-Y.; Pei J.-C.; Chang C.-Y.; Wang Y.-M.; Liu W.-C.; Wang T.-R.; Lai W.-S.; Chung-Chin Kuo Journal of Clinical Investigation1413
102016Modulation of NMDA channel gating by Ca2+ and Cd2+ binding to the external pore mouthTu Y.-C.; Yang Y.-C.; Chung-Chin Kuo Scientific Reports46
112016The Biophysical Basis Underlying Gating Changes in the p.V1316A Mutant Nav1.7 Channel and the Molecular Pathogenesis of Inherited ErythromelalgiaHuang C.-W.; Lai H.-J.; Huang P.-Y.; Lee M.-J.; Chung-Chin Kuo PLoS Biology53
122016A synergistic blocking effect of Mg2+ and spermine on the inward rectifier K+ (Kir2.1) channel poreHuang C.-W.; Chung-Chin Kuo Scientific Reports33
132015The temporal profiles of changes in nerve excitability indices in familial amyloid polyneuropathyLai H.-J.; Chiang Y.-W.; Yang C.-C.; Hsieh S.-T.; Chao C.-C.; Lee M.-J.; Chung-Chin Kuo PLoS ONE1010
142015Driving force-dependent block by internal Ba2+ on the Kir2.1 channel: Mechanistic insight into inward rectificationHsieh C.-P.; Chung-Chin Kuo ; Huang C.-W.Biophysical Chemistry44
152015Flow- and voltage-dependent blocking effect of ethosuximide on the inward rectifier K+ (Kir2.1) channelHuang C.-W.; Chung-Chin Kuo Pflugers Archiv European Journal of Physiology55
162015The differential contribution of GluN1 and GluN2 to the gating operation of the NMDA receptor channelTu Y.-C.; Chung-Chin Kuo Pflugers Archiv European Journal of Physiology77
172014Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficitsPan M.-K.; Tai C.-H.; Liu W.-C.; Pei J.-C.; Lai W.-S.; Chung-Chin Kuo Journal of Clinical Investigation1618
182014The bundle crossing region is responsible for the inwardly rectifying internal spermine block of the Kir2.1 channelHuang C.-W.; Chung-Chin Kuo Pflugers Archiv European Journal of Physiology88
192014The T-type calcium channel as a new therapeutic target for Parkinson's diseaseYang Y.-C.; Tai C.-H.; Pan M.-K.; Chung-Chin Kuo Pflugers Archiv European Journal of Physiology2325
202014Gating of the Kir2.1 Channel at the Bundle Crossing Region by Intracellular Spermine and Other CationsHuang C.-W.; Chung-Chin Kuo Journal of Cellular Physiology44
212012Subthalamic discharges as a causal determinant of parkinsonian motor deficitsTai C.-H.; Pan M.-K.; Lin J.J.; Huang C.-S.; Yang Y.-C.; Chung-Chin Kuo Annals of Neurology1616
222011Functional extension of amino acid triads from the fourth transmembrane segment (S4) into its external linker in Shaker K + channelsYang Y.-C.; Lin S.; Chang P.-C.; Lin H.-C.; Chung-Chin Kuo Journal of Biological Chemistry44
232011Modulation of subthalamic T-type Ca2+ channels remedies locomotor deficits in a rat model of Parkinson diseaseTai C.-H.; Yang Y.-C.; Pan M.-K.; Huang C.-S.; Chung-Chin Kuo Journal of Clinical Investigation3944
242010Lidocaine, carbamazepine, and imipramine have partially overlapping binding sites and additive inhibitory effect on neuronal Na+ channelsYang Y.-C.; Huang C.-S.; Chung-Chin Kuo Anesthesiology3033
252010Ionic flow enhances low-affinity binding: a revised mechanistic view into Mg2+ block of NMDA receptorsYang Y.-C.; Lee C.-H.; Chung-Chin Kuo Journal of Physiology1212
262010Parkinson's disease and cortico-basal ganglia circuitsPan M.-K.; Tai C.-H.; Chung-Chin Kuo Acta Neurologica Taiwanica10
272009The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na+ channelYang Y.-C.; Hsieh J.-Y.; Chung-Chin Kuo Journal of General Physiology2019
282008Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptorChang H.-R.; Chung-Chin Kuo Journal of Medicinal Chemistry2013
292008The activation gate and gating mechanism of the NMDA receptorChang H.-R.; Chung-Chin Kuo Journal of Neuroscience7071
302007A hydrophobic element secures S4 voltage sensor in position in resting Shaker K+ channelsYang Y.-C.; Own C.-J.; Chung-Chin Kuo Journal of Physiology99
312007Extracellular proton-modulated pore-blocking effect of the anticonvulsant felbamate on NMDA channelsChang H.-R.; Chung-Chin Kuo Biophysical Journal64
322007Characterization of the gating conformational changes in the felbamate binding site in NMDA channelsChang H.-R.; Chung-Chin Kuo Biophysical Journal1010
332006Electrophysiology of subthalamic nucleus in normal and Parkinson's diseaseTai C.-H.; Chung-Chin Kuo Acta Neurologica Taiwanica20
342005An inactivation stabilizer of the Na+ channel acts as an opportunistic pore blocker modulated by external Na+Yang Y.-C.; Chung-Chin Kuo Journal of General Physiology1818
352004Block of tetrodotoxin-resistant Na+ channel pore by multivalent cations: Gating modification and Na+ flow dependenceChung-Chin Kuo ; Chen W.-Y.; Yang Y.-C.Journal of General Physiology2926
362004Use-Dependent Inhibition of the N-Methyl-D-aspartate Currents by Felbamate: A Gating Modifier with Selective Binding to the Desensitized ChannelsChung-Chin Kuo ; Lin B.-J.; Chang H.-R.; Hsieh C.-P.Molecular Pharmacology3429
372003The position of the fourth segment of domain 4 determines status of the inactivation gate in Na+ channelsYang Y.-C.; Chung-Chin Kuo Journal of Neuroscience2518
382002Inhibition of Na + current by imipramine and related compounds: Different binding kinetics as an inactivation stabilizer and as an open channel blockerYang Y.-C.; Chung-Chin Kuo Molecular Pharmacology5552
392002Effect of Na+ flow on Cd2+ block of tetrodotoxin-resistant Na+ channelsChung-Chin Kuo ; Lin T.-J.; Hsieh C.-P.Journal of General Physiology1615
402001Recovery from inactivation of T-type Ca2+ channels in rat thalamic neuronsChung-Chin Kuo ; Yang S.Journal of Neuroscience3232
412000Facilitation of recovery from inactivation by external NA+ and location of the activation gate in neuronal NA+ channelsChung-Chin Kuo ; Liao S.-Y.Journal of Neuroscience1919
422000Inhibition of Na+ current by diphenhydramine and other diphenyl compounds: Molecular determinants of selective binding to the inactivated channelsChung-Chin Kuo ; Huang R.-C.; Lou B.-S.Molecular Pharmacology7374
431999K + binding sites and interactions between permeating K+ ions at the external pore mouth of an inward rectifier K+ channel (Kir2.1)Shieh R.-C.; Chang J.-C.; Chung-Chin Kuo Journal of Biological Chemistry1515
441999Zn2+ modulation of neuronal transient K+ current: Fast and selective binding to the deactivated channelsChung-Chin Kuo ; Chen F.-P.Biophysical Journal1718
451998Imipramine inhibition of transient K+ current: An external open channel blocker preventing fast inactivationChung-Chin Kuo Biophysical Journal3031
461998A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channelsChung-Chin Kuo Molecular Pharmacology174155
471997Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neuronesChung-Chin Kuo ; Lu L.British Journal of Pharmacology117109
481997Deactivation retards recovery from inactivation in Shaker K+ channelsChung-Chin Kuo Journal of Neuroscience78
491997Carbamazepine inhibition of neuronal Na+ currents: Quantitative distinction from phenytoin and possible therapeutic implicationsChung-Chin Kuo ; Chen R.-S.; Lu L.; Chen R.-C.Molecular Pharmacology126125
501995Postnatal development of cortical acetylcholinesterase-rich neurons in the rat brain: Permanent and transient patternsGeula C.; Mesulam M.-M.; Chung-Chin Kuo ; Tokuno H.Experimental Neurology2929
511994Na+ channels must deactivate to recover from inactivationChung-Chin Kuo ; Bean B.P.Neuron237243
521994Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neuronsChung-Chin Kuo ; Bean B.P.Molecular Pharmacology166166
531993Ion permeation through the L-type Ca2+ channel in rat phaeochromocytoma cells: two sets of ion binding sites in the pore.Chung-Chin Kuo ; Hess P.The Journal of Physiology9498
541993Block of the L-type Ca2+ channel pore by external and internal Mg2+ in rat phaeochromocytoma cells.Chung-Chin Kuo ; Hess P.The Journal of Physiology6060
551993Characterization of the high-affinity Ca2+ binding sites in the L-type Ca2+ channel pore in rat phaeochromocytoma cells.Chung-Chin Kuo ; Hess P.The Journal of Physiology8282
561993G-protein modulation of ion permeation through N-type calcium channelsChung-Chin Kuo ; Bean B.P.Nature5268
571992A functional view of the entrances of L-type Ca2+ channels: estimates of the size and surface potential at the pore mouthsChung-Chin Kuo ; Hess P.Neuron2934