研究成果


第 1 到 80 筆結果，共 80 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Engineered EVs with pathogen proteins: promising vaccine alternatives to LNP-mRNA vaccinesZhang, Bin; Sim, Wei Kian; TANG-LONG SHEN ; Lim, Sai KiangJournal of biomedical science
22024Liquid-State Fermented Ganoderma lucidum GANO99 Regulates Gut Microbiota and Concomitantly Modulates the Behavioral Deficits and Neurohistopathological Hallmarks of Alzheimer's Disease in a Preclinical Transgenic Mouse Model of Alzheimer's DiseaseWEI-JEN CHEN; Wei, Yu Shan; Lo, Hsin I.; Chu, Hui Fang; Tseng, Ming Chung; Lee, Bao Hong; TANG-LONG SHEN Journal of Food Biochemistry
32023Tomato-fruit-derived extracellular vesicles inhibit Fusobacterium nucleatum via lipid-mediated mechanismLee, Bao-Hong; Wu, She-Ching; Chien, Hao-Yuan; TANG-LONG SHEN ; Hsu, Wei-HsuanFood & function20
42022應用微生物學由學術實作轉譯至產業之系統應用教學TANG-LONG SHEN ; 沈湯龍教育部教學實踐研究計畫
52022The Role of Small Extracellular Vesicles in the Progression of Colorectal Cancer and Its Clinical ApplicationsLI-CHUN CHANG ; HAN-MO CHIU ; MING-SHIANG WU ; TANG-LONG SHEN International Journal of Molecular Sciences65
62021Exploration of the Proteomic Landscape of Small Extracellular Vesicles in Serum as Biomarkers for Early Detection of Colorectal NeoplasiaLI-CHUN CHANG ; Hsu, Yi-Chiung; HAN-MO CHIU ; Ueda, Koji; MING-SHIANG WU ; Kao, Chiun-How; TANG-LONG SHEN Frontiers in oncology77
72021Multi-Layer Reflectivity Calculation Based Meta-Modeling of the Phase Mapping Function for Highly Reproducible Surface Plasmon Resonance BiosensingWu T.-H; Yang C.-H; Chang C.-C; Liu H.-W; Yang C.-Y; CHII-WANN LIN ; TANG-LONG SHEN Biosensors33
82021The applications of Lactobacillus plantarum-derived extracellular vesicles as a novel natural antibacterial agent for improving quality and safety in tuna fishLee, B.-H.; Wu, S.-C.; TANG-LONG SHEN ; Hsu, Y.-Y.; Chen, C.-H.; Hsu, W.-H.Food Chemistry39
92021Cryptic diversity, molecular systematics, and pathogenicity of genus pestalotiopsis and allied genera causing gray blight disease of tea in Taiwan, with a description of a new pseudopestalotiopsis speciesTsai I; Chung C.-L; Lin S.-R; Hung T.-H; Shen T.-L; Hu C.-Y; Hozzein W.N; CHIA-LIN CHUNG ; Hiran Anjana Ariyawansa ; TANG-LONG SHEN ; TING-HSUAN HUNG Plant Disease1813
102021Amelioration of 5-fluorouracil-induced intestinal mucositis by Streptococcus thermophilus ST4 in a mouse modelShen S.-R; Chen W.-J; Chu H.-F; Wu S.-H; Wang Y.-R; TANG-LONG SHEN PLoS ONE12
112021Investigating the viral suppressor HC-pro inhibiting small rna methylation through functional comparison of HEN1 in angiosperm and bryophyteSanobar N; Lin P.-C; Pan Z.-J; Fang R.-Y; Tjita V; Chen F.-F; Wang H.-C; Tsai H.-L; Wu S.-H; Shen T.-L; Chen Y.-H; TANG-LONG SHEN ; SHIH-SHUN LIN ; HUANG-LUNG TSAI Viruses1614
122021Lysophosphatidic acid receptors 2 and 3 regulate erythropoiesis at different hematopoietic stagesChiang, J.-C.; Chen, W.-M.; Lin, K.-H.; Hsia, K.; Ho, Y.-H.; Lin, Y.-C.; Shen, T.-L. ; Lu, J.-H.; Chen, S.-K. ; Yao, C.-L.; Chen, B.P.C.; HSIN-YU LEE Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids54
132020Erratum: Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 (Open Biology (2020) 10 (190273) DOI: 10.1098/rsob.190273)Hung I.-C; Chen T.-M; Lin J.-P; Tai Y.-L; Shen T.-L; TANG-LONG SHEN ; SHYH-JYE LEE Open Biology00
142020The role of extracellular vesicles in prostate cancer with clinical applicationsTai, Y.-L.; Lin, C.-J.; TSAI-KUN LI ; Shen, T.-L.; Hsieh, J.-T.; TANG-LONG SHEN Endocrine-Related Cancer1211
152020Antifungal activity of morpholine and piperidine based surfactantsWieczorek, D.; Kwaśniewska, D.; Hsu, L.-H.; TANG-LONG SHEN ; YING-LIEN CHEN Tenside, Surfactants, Detergents4
162020Molecular networking as a dereplication strategy for monitoring metabolites of natural product treated cancer cellsGao, Y.-L.; Wang, Y.-J.; Chung, H.-H.; Chen, K.-C.; TANG-LONG SHEN ; Hsu, C.-C.Rapid Communications in Mass Spectrometry14
172020Gemini quaternary ammonium compound PMT12-BF4 inhibits Candida albicans via regulating iron homeostasisHsu, L.-H.; Kwaśniewska, D.; Wang, S.-C.; TANG-LONG SHEN ; Wieczorek, D.; YING-LIEN CHEN Scientific Reports910
182020Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42Hung, I.-C.; Chen, T.-M.; Lin, J.-P.; Tai, Y.-L.; Shen, T.-L.; SHYH-JYE LEE ; TANG-LONG SHEN Open Biology88
192020The future of Extracellular Vesicles as Theranostics–an ISEV meeting reportSoekmadji C; TANG-LONG SHEN et al. Journal of Extracellular Vesicles
202020Precision biomarker discovery powered by microscopy image fusion-assisted high spatial resolution ambient ionization mass spectrometry imagingLin, L.-E.; Chen, C.-L.; Huang, Y.-C.; Chung, H.-H.; Lin, C.-W.; Chen, K.-C.; Peng, Y.-J.; Ding, S.-T. ; Wang, M.-Y.; Shen, T.-L. ; CHENG-CHIH HSU Analytica Chimica Acta2925
212019Activation of Aryl Hydrocarbon Receptor by Kynurenine Impairs Progression and Metastasis of NeuroblastomaWu, Pei-Yi; Yu, I-Shing; Lin, Yueh-Chien; Chang, Yu-Tzu; Chen, Chien-Chin; Lin, Kuan-Hung; Tseng, Tzu-Hsuan; Kargren, Mati; Tai, Yu-Ling; Shen, Tang-Long; Liu, Yen-Lin; Wang, Bo-Jeng; Chang, Chi-Hao; Chen, Wei-Min; Juan, H.-F. ; Huang, Shiu-Feng; Chan, Ya-Yun; Liao, Yung-Feng; WEN-MING HSU ; TANG-LONG SHEN Cancer research2927
222019Deep Lipidomics and Molecular Imaging of Unsaturated Lipid Isomers: A Universal Strategy Initiated by mCPBA EpoxidationKuo, T.-H.; Chung, H.-H.; Chang, H.-Y.; Lin, C.-W.; Wang, M.-Y.; Shen, T.-L.; TANG-LONG SHEN Analytical Chemistry8378
232019Grb7, a Critical Mediator of EGFR/ErbB Signaling, in Cancer Development and as a Potential Therapeutic TargetChu, Pei-Yu; Tai, Yu-Ling; TANG-LONG SHEN Cells
242019The paracrine induction of prostate cancer progression by caveolin-1Lin, C.-J.; Yun, E.-J.; Lo, U.-G.; Tai, Y.-L.; Deng, S.; Hernandez, E.; Dang, A.; Chen, Y.-A.; Saha, D.; Mu, P.; Lin, H.; TSAI-KUN LI ; Shen, T.-L.; Lai, C.-H.; TANG-LONG SHEN Cell Death and Disease3937
252019Basics and applications of tumor-derived extracellular vesiclesTai Y.-L.; Chu P.-Y.; Lee B.-H.; Chen K.-C.; Yang C.-Y.; WEN-HUNG KUO ; TANG-LONG SHEN Journal of Biomedical Science4741
262018LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancerLin Y.-C.; Chen C.-C.; Chen W.-M.; Lu K.-Y.; Shen T.-L. ; Jou Y.-C.; Shen C.-H.; Ohbayashi N.; Kanaho Y.; Huang Y.-L.; H. Lee Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids1817
272018Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathwaysChen K.-Y.; Lin J.-A.; Yao H.-Y.; Hsu A.-C.; Tai Y.-T.; Chen J.-T.; Hsieh M.-C.; TANG-LONG SHEN ; Hsu R.-Y.; Wu H.-T.; Wang G.H.; Ho B.-Y.; Chen Y.-P.Nutrition Research
282018Adiponectin and adiponectin receptor 1 overexpression enhance inflammatory bowel diseasePeng Y.-J.; Shen T.-L.; Chen Y.-S.; Mersmann H.J.; Liu B.-H.; TANG-LONG SHEN ; Ding, S.-T. Journal of Biomedical Science3026
292018Exosomes in cancer development and clinical applicationsTai Y.-L.; Chen K.-C.; Hsieh J.-T.; TANG-LONG SHEN Cancer Science
302018A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancerWang P.-S.; Chou C.-H.; Lin C.-H.; Yao Y.-C.; Cheng H.-C.; Li H.-Y.; Chuang Y.-C.; Yang C.-N.; Ger L.-P.; Chen Y.-C.; Lin F.-C.; TANG-LONG SHEN ; Hsiao M.; Lu P.-J.Oncogene
312016Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse modelHuang, C.-W.; Hong, T.-W.; Wang, Y.-J.; Chen, K.-C.; Pei, J.-C.; Chuang, T.-Y. ; Lai, W.-S.; Tsai, S.-H.; Chu, R.; Chen, W.-C.; Sheen, L.-Y.; Takahashi, S.; Ding, S.-T. ; TANG-LONG SHEN ; WEN-SUNG LAI ; Sheen L.-Y. BMC Complementary and Alternative Medicine1916
322016Regulation of EBV LMP1-triggered EphA4 downregulation in EBV-associated B lymphoma and its impact on patients' survivalHuang, Ya-Chi; Lin, Sue-Jane; Lin, Kai-Min; Chou, Ya-Ching; CHUNG-WU LIN ; SHAN-CHI YU ; Chen, Chi-Long; TANG-LONG SHEN ; Chen, Chi-Kuan; Lu, Jean; MEI-RU CHEN ; CHING-HWA TSAI Blood2219
332016Grb7 protein stability modulated by pin1 in association with cell cycle progressionTai, Y.-L., Tung, L.-H., Lin, Y.-C., Lu, P.-J., Chu, P.-Y., Wang, M.-Y., Huang, W.-P., Chen, K.-C., Lee, H., Shen, T.-L.; Tung L.-H.; Lin Y.-C.; Lu P.-J.; Chu P.-Y.; Wang M.-Y.; Huang W.-P.; Chen K.-C.; Lee H.; TANG-LONG SHEN ; WEI-PANG HUANG ; HSINYU LEE PLoS ONE66
342016Surface and Antimicrobial Activity of SulfobetainesWieczorek, D.; Gwiazdowska, D.; Staszak, K.; YING-LIEN CHEN ; TANG-LONG SHEN Journal of Surfactants and Detergents
352016Activation of focal adhesion kinase through an interaction with β4 integrin contributes to tumorigenicity of colon cancerTai, Y.-L.; I-RUE LAI ; Peng, Y.-J.; Ding, S.-T. ; TANG-LONG SHEN FEBS Letters2423
362015Tumour exosome integrins determine organotropic metastasis.TANG-LONG SHEN 32253110
372015Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.TANG-LONG SHEN 18841773
382015Emerging roles of focal adhesion kinase in cancer.TANG-LONG SHEN 170162
392015Establishment of a rapid PCR detection method for Antrodia salmonea and A. cinnamomeaWu, M.-L.; TANG-LONG SHEN ; Chang, T.-T.; Chen, C.-H.; Hung, T.-H.; Lee, C.-Y.; Lin, C.-Y.Taiwan Journal of Forest Science
402015Multiplex detection, distribution, and genetic diversity of Hop stunt viroid and citrus exocortis viroid infecting citrus in TaiwanLin, C.-Y.; Wu, M.-L.; TANG-LONG SHEN ; Yeh, H.-H.; TING-HSUAN HUNG Virology Journal
412015A mutual titer-enhancing relationship and similar localization patterns between Citrus exocortis viroid and Hop stunt viroid co-infecting two citrus cultivarsLin, C.-Y.; Wu, M.-L.; TANG-LONG SHEN ; TING-HSUAN HUNG Virology Journal
422015Characterization and application of a common epitope recognized by a broad-spectrum C4 monoclonal antibody against capsid proteins of plant potyvirusesLiu, H.-L.; Liu, Y.-W.; TANG-LONG SHEN ; CHUN-HUA HSU ; YA-CHUN CHANG Applied Microbiology and Biotechnology1
432014DNA topoisomerase III alpha regulates P53-mediated tumor suppressionHsieh, Mei-Yi; Fan, Jia-Rong; Chang, Han-Wen; Chen, Hsiang-Chin; TANG-LONG SHEN ; SHU-CHUN TENG ; Yeh, Yen-Hsiu; TSAI-KUN LI Clinical Cancer Research108
442013Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.TANG-LONG SHEN 4340
452012Micropatterning of mammalian cells on inorganic-based nanosponges.TANG-LONG SHEN 2016
46201214-3-3σ regulates β-catenin-mediated mouse embryonic stem cell proliferation by sequestering GSK-3βChang T.-C.; Liu C.-C.; Hsing E.-W.; Liang S.-M.; Chi Y.-H.; Sung L.-Y.; Lin S.-P.; Shen T.-L.; BOR-SHENG KO ; Yen B.L.; Yet S.-F.; Wu K.K.; TANG-LONG SHEN ; LI-YING SUNG ; SHAU-PING LIN PLoS ONE2224
472012Solution structure of the oncogenic MIEN1 protein reveals a thioredoxin-like fold with a redox-active motif.TANG-LONG SHEN ; CHUN-HUA HSU 1311
482011Serum amyloid A induces lipolysis by downregulating perilipin through ERK1/2 and PKA signaling pathways.Liu, LR; Lin S.P.; Chen C.C.; Chen Y.J.; Tai C.C.; Chang S.C.; Juang R.H.; Tseng Y.W.; Liu B.H.; Mersmann H.J.; Shen T.L.; RONG-HUAY JUANG ; SHIH-TORNG DING ; SHIH-CHUNG CHANG ; TANG-LONG SHEN ; SHAU-PING LIN 3028
492011Increased expression of 14-3-3β promotes tumor progression and predicts extrahepatic metastasis and worse survival in hepatocellular carcinomaLiu T.-A.; Jan Y.-J.; BOR-SHENG KO ; Chen S.-C.; Liang S.-M.; Hung Y.-L.; CHIUN HSU ; TANG-LONG SHEN ; Lee Y.-M.; Chen P.-F.; Wang J.; Shyue S.-K.; Liou J.-Y.American Journal of Pathology3838
502011The function of porcine PPARγ and dietary fish oil effect on the expression of lipid and glucose metabolism related genesYu, Yu-Hsiang; Wu, Shinn-Chih ; Cheng, Winston Teng-Kuei; Mersmann, Harry J.; Shen, Tang-Long ; Ding, Shih-Torng The Journal of Nutritional Biochemistry2726
512011Interactions between cells and nanoscale surfaces of oxidized silicon substratesTANG-LONG SHEN World Academy of Science, Engineering and Technology0
522010Recruitment and activation of FAK by integrin beta4 in an EGF-Src dependent manner participate in tumorigenesisTai, Yu-Ling; Chu, Pei-Yu; Lai, I-Rui; Tseng, Hui-Yuan; Mossaad, Abdel-Ghany; Pauli, Bendicht; Liou, Jun-Yang; Guan, Jun-Lin; Shen, Tang-Long Journal of Cell Biology
532010Resonance assignments of human C35 (C17orf37) protein, a novel tumor biomarker.TANG-LONG SHEN ; CHUN-HUA HSU 44
542010Phosphorylation of focal adhesion kinase at Tyr397 in gastric carcinomas and its clinical significanceI-RUE LAI ; TANG-LONG SHEN ; Lin H.-S.; Liou J.-Y.; Jan Y.-J.; JEN-CHIEH LEE American Journal of Pathology5251
552010Preliminary crystallographic characterization of the Grb2 SH2 domain in complex with a FAK-derived phosphotyrosyl peptideChen, H.-H.; Chen, C.-W.; Chang, Y.-Y.; TANG-LONG SHEN ; CHUN-HUA HSU Acta Crystallographica Section F: Structural Biology and Crystallization Communications
562009Cell adhesion, morphology and biochemistry on nano-topographic oxidized silicon surfacesYang, Chung-Yao; Lee, Chia-Yao; Shen, Tang-Long ; Yeh, J. AndrewEuropean Cells and Materials760
572009Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis.TANG-LONG SHEN 4444
582009Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesisChu P.-Y.; Huang L.-Y.; Hsu C.-H.; Liang C.-C.; Guan J.-L.; Hung T.-H.; TING-HSUAN HUNG ; Hsu, Chun-Hua ; Shen, Tang-Long Journal of Biological Chemistry5151
592009血清澱粉狀蛋白A藉由細胞外訊息調節蛋白激酶與蛋白質激酶A訊息傳遞路徑降低油滴包被蛋白增進脂肪分解作用劉利儒; 林紹品; 戴甄真; 陳郁仁; 張世宗 ; 莊榮輝 ; 曾郁雯; 劉秉勳; 沈湯龍 ; 丁詩同 中國畜牧學會會誌 
602008煙草嵌紋病毒p126蛋白做為基因靜默抑制子之生化和遺傳分析　（新制多年期第1年）沈湯龍 
612008Focal adhesion kinase (FAK)的整合性調控訊息之研究　（新制多年期第1年）沈湯龍 
622008Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.Lutu-Fuga, KM; TANG-LONG SHEN ; Weis, SM; Lim, S-T; Lutu-Fuga, KM; Barnes, LA; Chen, X.L.; Gothert, J.R.; Shen, T-L; Guan, J-L; Schlaepfer, DD; Cheresh, DA
632008Ammonium hydroxide extracts from black tea inhibit growth, migration and invasion of colon cancer cellsHsiu-Chin Huang; Hsiao-Yu Chen; CHIA-YANG CHEN ; TANG-LONG SHEN ; JOHN HUANG ; NENG-YU LIN ; Shao-Yin Sum; Mei-Ieng Che; MIN-CHUAN HUANG Journal of Food Biochemistry00
642007Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland.Tamas Nagy; Huijun Wei; TANG-LONG SHEN ; Xu Peng; Chun-Chi Liang; Boyi Gan; Jun-Lin Guan
652007Integrin β4 與 focal adhesion kinase (FAK) 結合在腫瘤進程的角色(2/2)沈湯龍 
662007β1,4-N-acetylgalactosaminyltransferase III enhances malignant phenotypes of colon cancer cellsJOHN HUANG ; JIN-TUNG LIANG ; Hsiu-Chin Huang; Shen, Tang-Long ; Hsiao-Yu Chen; NENG-YU LIN ; Mei-Ieng Che; WEI-CHOU LIN ; MIN-CHUAN HUANG Molecular Cancer Research3333
672006Inactivation of focal adhesion kinase in cardiomyocytes promotes cardiac eccentric hypertrophy and fibrosis in miceXu Peng; Marc S. Kraus; Huijun Wei; Tang-Long Shen ; Romain Pariaut; Ana Alcaraz; Guangju Ji; Lihong Cheng; Qinglin Yang; Michael I. Kotlikoff; Ju ChenJournal of Clinical Investigation127118
682005Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis.TANG-LONG SHEN ; Ann Y.-J. Park; Ana Alcaraz; Xu Peng; Ihnkyung Jang; P; elakis Koni; Richard A. Flavell; Hua Gu; Jun-Lin Guan
692005Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases.Hui Miao; Klaus Strebhardt; Elena B. Pasquale; TANG-LONG SHEN ; Jun-Lin Guan; Bingcheng Wang
702004Activation of FAK and Src are receptor-proximal events required for netrin signalingWeiquan Li; Shen,Tang-Long et al. Nature191179
712004Grb7 in intracellular signaling and its role in cell regulationShen, Tang-Long ; Jun-Lin GuanFrontiers in Bioscience6466
722004Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic micePeng, X.; Ueda, H.; Zhou, H.; Stokol, T.; Shen, T. L. ; Alcaraz, A.; Nagy, T.; Vassalli, J. D.Cardiovascular Research 649387
732003Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction.TANG-LONG SHEN 145139
742002EphB1 associates with Grb7 and regulates cell migration.TANG-LONG SHEN 6869
752002Association of Grb7 with phosphoinositides and its role in the regulation of cell migration.TANG-LONG SHEN 4748
762002The association of Grb7 with phosphoinositides regulates cell migrationShen, Tang-Long ; Han, DongCho; Guan, Jun-LinThe Journal of Biological Chemistry 
772002Nck-2 interacts with focal adhesion kinase and modulates cell motilityGoicoechea, Silvia M.; Tu, Yizeng; Hua, Yun; Chen, Ka; Shen, Tang-Long ; Guan, Jun-Lin; Wu, ChuanyueThe International Journal of Biochemistry & Cell Biology3133
782001The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions.TANG-LONG SHEN 144145
792001Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts.Shen, Tang-Long ; Guan, Jun-LinFEBS Letters8484
802000Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migrationDongCho Han, Tang-Long Shen ,; TANG-LONG SHEN J Biol. Chem9487