計畫


第 1 到 44 筆結果，共 44 筆。

啟始時間標題P-Investigator經費來源
2023Structure-Based Mechanistic Dissection into the Regulation of Reversed Fork Stability (V)NEI-LI CHANNational Science and Technology Council
2023Constructing a Widely Applicable Enzyme Library by Harnessing the Unique Catalytic Versatility of Fe/Αkg-Dependent Enzymes and Elucidating the Structural Basis Underlying Their Functional PlasticityNEI-LI CHANNational Science and Technology Council
2023人力結構改善-操作顯微鏡、數位影像及協助設計實驗與分析數據NEI-LI CHANHigher Education Sprout Project
2023Taiwan Cryo-EM ConsortiumNEI-LI CHANNational Science and Technology Council
2023維繫基因體動態及完整性之核酸處理機組的結構解析NEI-LI CHANHigher Education Sprout Project
2023Cryo-Electron Microscopy Core LaboratoryNEI-LI CHANHigher Education Sprout Project
2022Constructing a Widely Applicable Enzyme Library by Harnessing the Unique Catalytic Versatility of Fe/Αkg-Dependent Enzymes and Elucidating the Structural Basis Underlying Their Functional PlasticityNEI-LI CHANNational Science and Technology Council
2022Structure-Based Mechanistic Dissection into the Regulation of Reversed Fork Stability (IV)NEI-LI CHANNational Science and Technology Council
2022Discovery and Development of Small Molecules with the Aid of Ai-Based Approaches for Therapeutic Intervention of Huntington’s Disease ( II )NEI-LI CHANNational Science and Technology Council
2022人力結構改善-操作顯微鏡、數位影像及協助設計實驗與分析數據NEI-LI CHANHigher Education Sprout Project
2022Structure-Based Mechanistic Dissection of the C－C and C－O Bond Formation Catalyzed by Α-Ketoglutarate-Dependent Non-Heme Iron Enzymes and the Construction of a Chemically Versatile Enzyme LibraryNEI-LI CHANHigher Education Sprout Project
2022維繫基因體動態及完整性之核酸處理機組的結構解析NEI-LI CHANHigher Education Sprout Project
2021Discovery and Development of Small Molecules with the Aid of Ai-Based Approaches for Therapeutic Intervention of Huntington’s Disease ( I )NEI-LI CHANNational Science and Technology Council
2021Structure-Based Mechanistic Dissection into the Regulation of Reversed Fork Stability( III )NEI-LI CHANNational Science and Technology Council
2021Structure-Based Mechanistic Dissection of the C－C and C－O Bond Formation Catalyzed by Α-Ketoglutarate-Dependent Non-Heme Iron Enzymes and the Construction of a Chemically Versatile Enzyme LibraryNEI-LI CHANNational Science and Technology Council
2021人力結構改善-操作顯微鏡、數位影像及協助設計實驗與分析數據NEI-LI CHANHigher Education Sprout Project
2021維繫基因體動態及完整性之核酸處理機組的結構解析NEI-LI CHANHigher Education Sprout Project
2020Structure-Based Mechanistic Dissection into the Regulation of Reversed Fork Stability( II )NEI-LI CHANNational Science and Technology Council
2020Structure-Based Dissection of the Catalytic Mechanisms of Α-Ketoglutarate-Dependent Non-Heme Iron Enzymes and the Construction of an Enzyme Library by Exploiting the Reactivity of Oxoferryl IntermediateNEI-LI CHANNational Science and Technology Council
2020以X-射線晶體學及冷凍電子顯微鏡技術解析端粒結合蛋白複合體之立體結構NEI-LI CHANHigher Education Sprout Project
2020Planning and Promotion of the Research in Biological SciencesNEI-LI CHANNational Science and Technology Council
2019Structure-Based Mechanistic Dissection into the Regulation of Reversed Fork Stability( I )NEI-LI CHANNational Science and Technology Council
2019An Integrated Structural, Biochemical, and Computational Dissection of the Assembly and Operation of the Type II Topoisomerase-Mediated DNA GateNEI-LI CHANNational Science and Technology Council
2019Structural insight into the mechanism of AsqJ-catalyzed consecutive oxidation reactionsNEI-LI CHANHigher Education Sprout Project
2019操作顯微鏡、數位影像及協助設計實驗與分析數據NEI-LI CHANHigher Education Sprout Project
2019Planning and Promotion of the Research in Biological SciencesNEI-LI CHANNational Science and Technology Council
2018An Integrated Structural, Biochemical, and Computational Dissection of the Assembly and Operation of the Type II Topoisomerase-Mediated DNA GateNEI-LI CHANNational Science and Technology Council
2017An Integrated Structural, Biochemical, and Computational Dissection of the Assembly and Operation of the Type II Topoisomerase-Mediated DNA GateNEI-LI CHANNational Science and Technology Council
2017以X-射線晶體學及冷凍電子顯微鏡技術解析端粒結合蛋白複合體之立體結構NEI-LI CHANHigher Education Sprout Project
2016Structural Basis of Antizyme-Mediated Recognition and Degradation of Its Target ProteinsNEI-LI CHANNational Science and Technology Council
2015Structural Basis of Antizyme-Mediated Recognition and Degradation of Its Target ProteinsNEI-LI CHANNational Science and Technology Council
2014Structural Basis of Antizyme-Mediated Recognition and Degradation of Its Target ProteinsNEI-LI CHANNational Science and Technology Council
2013Structural Basis of Antizyme-Mediated Proteosomal Degradation PathwayNEI-LI CHANNational Science and Technology Council
2013Structural-Based Design of Topoisomerase II Isozyme-Specific Anticancer Agents (III)NEI-LI CHANNational Science and Technology Council
2013Electronic management for the 1st core facility in translational medicineNEI-LI CHANNTUH
2012X-Ray Crystallographic Analyses of Human Type II Topoisomerases Top2alpha and Top2beta and Their Complexes with DNA and Antitumor AgentsNEI-LI CHANNational Science and Technology Council
2012Structural-based Design of Topoisomerase II Isozyme-Specific Anticancer Agents (II)NEI-LI CHANNational Science and Technology Council
2011X-Ray Crystallographic Analyses of Human Type II Topoisomerases Top2alpha and Top2beta and Their Complexes with DNA and Antitumor AgentsNEI-LI CHANNational Science and Technology Council
2011Structural-Based Design of Topoisomerase II Isozyme-Specific Anticancer Agents (INEI-LI CHANNational Science and Technology Council
2010X-Ray Crystallographic Analyses of Human Type II Topoisomerases Top2alpha and Top2beta and Their Complexes with DNA and Antitumor AgentsNEI-LI CHANNational Science and Technology Council
2009X-Ray Crystallographic Studies of Prostacyclin Synthase and Thromboxane Synthase---Characterize the Structures of Two Non-Classical Cytochrome P450 EnzymesNEI-LI CHANNational Science and Technology Council
2008X-Ray Crystallographic Analyses of the Hepatitis B Virus Reverse Transcriptase and X ProteinNEI-LI CHANNational Science and Technology Council
2008X-Ray Crystallographic Studies of Prostacyclin Synthase and Thromboxane Synthase: Characterize the Structures of Two Non-Classical Cytochrome P450 Enzymes.NEI-LI CHANNational Science and Technology Council
2007X-Ray Crystallographic Studies of Prostacyclin Synthase and Thromboxane Synthase---Characterize the Structures of Two Non-Classical Cytochrome P450 EnzymesNEI-LI CHANNational Science and Technology Council